GEO DataSet Links for PMC (Select 5547506) - GEO DataSets

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Links from PMC

Items: 4

Select item 2000988611.

Large-scale genomic reorganizations of topological domains (TADs) at the HoxD locus (4C-Seq)

(Submitter supplied) The transcriptional activation of Hoxd genes during mammalian limb development involves dynamic interactions with the two Topologically Associating Domains (TADs) flanking the HoxD cluster. In particular, the activation of the most posterior Hoxd genes in developing digits is controlled by regulatory elements located in the centromeric TAD (C-DOM) through long-range contacts. To assess the structure-function relationships underlying such interactions, we measured compaction levels and TAD discreteness using a combination of chromosome conformation capture (4C-seq) and DNA FISH. more...

Organism:: Mus musculus

Type:: Other

Platform:: GPL17021
12 Samples

Download data: BEDGRAPH

Series

Accession:: GSE98861

ID:: 200098861

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000982332.

Large-scale genomic reorganizations of topological domains (TADs) at the HoxD locus

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other

Platform:: GPL17021
15 Samples

Download data: BEDGRAPH, BW

Series

Accession:: GSE98233

ID:: 200098233

PubMed Full text in PMC Similar studies

Select item 2000982323.

Analysis of gene expression in the distal forelimbs in 2.4Mb inversion adjacent to the HoxD cluster

(Submitter supplied) E12.5 mouse distal forelimb embryonic transcriptome

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL17021
2 Samples

Download data: BW, TXT

Series

Accession:: GSE98232

ID:: 200098232

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000965584.

ChIP-seq analysis of CTCF in distal limbs at mouse E12.5 using anti-CTCF

(Submitter supplied) We performed ChIP-seq for CTCF using the autopod from E12.5 embryo and confirmed the binding pattern previously reported by a ChIP-on-Chip approach using the same embryonic tissue (Soshnikova et al., 2010). Our results show CTCF-mediated gating of long-range contacts at the HoxD locus.