GEO DataSet Links for SRA (Select 19211307) - GEO DataSets

Warning: The NCBI web site requires JavaScript to function. more...

Format

Summary
Summary (text)
Unique Identifier List

Sort by

Default order
Number of Samples (High to Low)
Number of Samples (Low to High)

Send to:

Choose Destination

File
Clipboard
Collections

Links from SRA

Items: 2

Select item 3058205181.

TGFBR1 mutant replicate 9

Organism:: Mus musculus

Source name:: Esophagus

Platform:: GPL17021
Series:: GSE193756

Download data

Sample

Accession:: GSM5820518

ID:: 305820518

SRA Run Selector

Select item 2001937562.

TGFbR signaling in squamous epithelial cells plays a fundamental role in controlling tissue specific allergic inflammation

(Submitter supplied) Allergic diseases are becoming a global health crisis. Individuals harboring loss-of-function variants in transforming growth factor beta receptor (TGFbR) have an increased prevalence of allergic disease, but the mechanisms responsible are poorly understood. We demonstrate that mice harboring a variant identified in patients spontaneously develop disease that clinically, immunologically, histologically, and transcriptionally recapitulates eosinophilic esophagitis, a condition characterized by allergic inflammation in the esophagus. more...