GEO DataSets

(Submitter supplied) Phenotypic evolution can result from gains and losses of genes, mutations in coding sequences, or regulatory mutations affecting gene expression. While the relative importance of these mechanisms is debated, regulatory evolution is recognized as a key driver of phenotypic diversity. In this study, we applied a phylogenetic model to discretized gene expression states (active or inactive) to investigate the evolutionary turnover of organ-specific transcriptomes, which we define as instances where gene expression is activated or deactivated in a particular organ. more...

Organism:

Drosophila ananassae; Drosophila eugracilis; Drosophila takahashii; Drosophila ficusphila; Drosophila kikkawai; Drosophila simulans; Drosophila elegans; Drosophila bipectinata; Drosophila biarmipes; Drosophila yakuba; Drosophila melanogaster

Type:

Expression profiling by high throughput sequencing

33 related Platforms

176 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Drosophila melanogaster; Drosophila mojavensis; Drosophila pseudoobscura; Drosophila bifasciata; Drosophila eugracilis

Type:

Non-coding RNA profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

5 related Platforms

27 Samples

Download data: BED, TXT

(Submitter supplied) Organisms require mechanisms to distinguish self and non-self RNA. This distinction is crucial to initiate the biogenesis of piRNAs. In Drosophila ovaries, PIWI-guided slicing and the recognition of piRNA precursor transcripts by the DEAD-box RNA helicase Yb are the two known mechanisms to initiate biogenesis in the germline and the soma, respectively. Both, the PIWI proteins and Yb are highly conserved across most Drosophila species and are thought to be essential to the piRNA pathway and for silencing TEs. more...

Organism:

Drosophila eugracilis; Drosophila bifasciata; Drosophila pseudoobscura

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL32665 GPL32664 GPL32666

4 Samples

Download data: BED

(Submitter supplied) Organisms require mechanisms to distinguish self and non-self RNA. This distinction is crucial to initiate the biogenesis of piRNAs. In Drosophila ovaries, PIWI-guided slicing and the recognition of piRNA precursor transcripts by the DEAD-box RNA helicase Yb are the two known mechanisms to initiate biogenesis in the germline and the soma, respectively. Both, the PIWI proteins and Yb are highly conserved across most Drosophila species and are thought to be essential to the piRNA pathway and for silencing TEs. more...

Organism:

Drosophila mojavensis; Drosophila eugracilis; Drosophila bifasciata; Drosophila melanogaster; Drosophila pseudoobscura

Type:

Non-coding RNA profiling by high throughput sequencing

5 related Platforms

17 Samples

Download data: BED, TXT

(Submitter supplied) The model organism Encyclopedia of DNA Elements project (modENCODE) has produced a comprehensive annotation of D. melanogaster transcript models based on an enormous amount of high-throughput experimental data. However, some transcribed elements may not be functional, and technical artifacts may lead to erroneous inference of transcription. Inter-species comparison provides confidence to predicted annotation, since transcriptional activity that has been evolutionarily conserved is likely to have an advantageous function. more...

Organism:

Drosophila melanogaster; Drosophila pseudoobscura; Drosophila mojavensis; Drosophila yakuba; Drosophila eugracilis; Drosophila takahashii; Drosophila ficusphila; Drosophila kikkawai; Drosophila bipectinata; Drosophila rhopaloa; Drosophila ananassae; Drosophila simulans; Drosophila virilis; Drosophila elegans; Drosophila biarmipes

Type:

Expression profiling by high throughput sequencing

34 related Platforms

93 Samples

Download data: BAM, BED, RPKM, TXT

(Submitter supplied) We performed transcriptional profiling of sexed whole adults and mixed sex embryos of eight Drosophila species. These data were used in a comparative transcriptomics analysis of multiple Drosophila species to define functional elements conserved throughout the Drosophila genus.

Organism:

Drosophila biarmipes; Drosophila eugracilis; Drosophila takahashii; Drosophila kikkawai; Drosophila rhopaloa; Drosophila elegans; Drosophila ficusphila; Drosophila bipectinata

Type:

Expression profiling by high throughput sequencing

16 related Platforms

26 Samples

Download data: RPKM, TXT