txid37003[Organism] - GEO DataSets

Select item 2001851861.

Molecular mechanisms of embryonic tail development in the self-fertilizing mangrove killifish Kryptolebias

(Submitter supplied) We report the application of single-molecule-based sequencing technology for high-throughput profiling of histone modifications in mammalian cells. By obtaining over four billion bases of sequence from chromatin immunoprecipitated DNA, we generated genome-wide chromatin-state maps of mouse embryonic stem cells, neural progenitor cells and embryonic fibroblasts. We find that lysine 4 and lysine 27 trimethylation effectively discriminates genes that are expressed, poised for expression, or stably repressed, and therefore reflect cell state and lineage potential. more...

Organism:: Kryptolebias marmoratus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL23686
5 Samples

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Series

Accession:: GSE185186

ID:: 200185186

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Select item 2001570852.

Diverse CGG binding proteins across eukaryotes produced by independent domestications of hAT transposons

(Submitter supplied) The human transcription factor (TF) CGGBP1 (“CGG Binding Protein”) is conserved only in amniotes, and is believed to derive from the zf-BED and Hermes transposase DNA-binding domains (DBDs) of a hAT DNA transposon. Here, we examine the DNA binding preferences of a wide variety of metazoan CGGBP1-like TFs with this bipartite domain using PBM experiments. The derived motifs are available at ...

Organism:: Aedes aegypti; Culex quinquefasciatus; Latimeria chalumnae; Cyprinus carpio; synthetic construct; Hucho hucho; Amphiprion ocellaris; Labeo rohita; Mola mola; Sphaeramia orbicularis; Anabarilius grahami; Locusta migratoria; Crocodylus porosus; Homo sapiens; Rhodnius prolixus; Rhipicephalus appendiculatus; Kryptolebias marmoratus; Nematostella vectensis; Acanthochromis polyacanthus; Hippocampus comes; Hofstenia miamia; Petromyzon marinus; Acipenser ruthenus; Gallus gallus; Erpetoichthys calabaricus; Rhizophagus irregularis; Paramormyrops kingsleyae; Acyrthosiphon pisum; Salmo salar; Fundulus heteroclitus; Sparus aurata; Chrysemys picta; Austrofundulus limnaeus; Anabas testudineus; Amphiprion percula; Salarias fasciatus

Type:: Other

Platform:: GPL11260
258 Samples

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Series

Accession:: GSE157085

ID:: 200157085

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Select item 2001010843.

Gene expression response to infection in self-fertilising fish

(Submitter supplied) Parasites are strong drivers of evolutionary change and the genetic variation of both host and parasite populations can co-evolve as a function of the parasite's virulence and the host's immune resistance. The role of transcriptome variation in specific interactions between host and parasite genotypes has been less studied and can be confounded by high genotypic variability in natural populations. We have analysed gene expression between two inbred lines of a self-fertilising fish experimentally infected with a parasite under controlled conditions, in order to estimate the role of the genotype in the transcriptome responses to infection using RNA-seq.