txid5482[Organism] - GEO DataSets

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Select item 2001512881.

Comparative transcriptomic analysis of the response of CUG-clade Candida species to phagocytosis

(Submitter supplied) Pathogenic Candida fungi are a leading cause of opportunistic, hospital-associated bloodstream infections with high mortality rates, typically in immunocompromised patients. Several species, including C. albicans, the most prevalent cause of infection, belong to the monophyletic CUG clade of yeasts. Much is known about the interaction of C. albicans with innate immune cells, which are crucial for controlling infection. more...

Organism:: Candida tropicalis; Candida parapsilosis; Clavispora lusitaniae; Candida albicans; Lodderomyces elongisporus; Mus musculus; Candida dubliniensis

Type:: Expression profiling by high throughput sequencing

12 related Platforms
24 Samples

Download data: TXT

Series

Accession:: GSE151288

ID:: 200151288

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001611362.

ChIP-seq of Ndt80 in a C. albicans, C. dubliniensis and C. tropicalis during biofilm formation in different media

(Submitter supplied) The purpose of this experiment was to identify the genes bound by the regulator Ndt80 in C. albicans, C. dubliniensis and C. tropicalis during biofilm formation in different growth media. Ndt80 was tagged with a c-myc epitope in the three species and the immunoprecipitation of the tagged strain was compared to that of an untagged control strain in two different media for each species.

Organism:: Candida albicans; Candida dubliniensis; Candida tropicalis

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL29382 GPL19036 GPL29383
24 Samples

Download data: TXT

Series

Accession:: GSE161136

ID:: 200161136

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001611333.

ChIP-seq of biofilm master regulators in four species of Candida

(Submitter supplied) The purpose of this experiment was to identify the genes bound by the biofilm master regulators (Bcr1, Brg1, Efg1, Ndt80, Rob1 and Tec2) in Candida albicans, C. dubliniensis, C. tropicalis and C. parapsilosis during biofilm formation. The regulators were tagged with a c-myc epitope and the immunoprecipitation of the tagged strain was compared to that of an untagged control strain.

Organism:: Candida tropicalis; Candida dubliniensis; Candida albicans; Candida parapsilosis

Type:: Genome binding/occupancy profiling by high throughput sequencing

6 related Platforms
61 Samples

Download data: TXT

Series

Accession:: GSE161133

ID:: 200161133

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001607804.

Gene Expression Arrays comparing C. tropicalis CEM010 during planktonic and biofilm growth in different media

(Submitter supplied) The goal was to identify genes that change their expression in biofilm vs. planktonic growth. Cultures for the extraction of total RNA under biofilm growth conditions were performed on biofilms grown on the bottom of 6-well polystyrene plates for 48 hours at 37°C and 200 rpm as previously described (Nobile et al. 2012). The media used was Spider 1% glucose and RPMI 1% glucose. Planktonic cultures for total RNA were grown in the same media by inoculating with cells from an overnight 30°C YPD culture to an OD600 of 0.05. more...

Organism:: Candida tropicalis

Type:: Expression profiling by array

Platform:: GPL29364
8 Samples

Download data: GPR

Series

Accession:: GSE160780

ID:: 200160780

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001607835.

Evolution of biofilm formation in Candida

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Candida albicans x Candida dubliniensis; Candida dubliniensis; Candida tropicalis; Candida albicans; Candida parapsilosis

Type:: Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing

11 related Platforms
127 Samples

Download data: GPR, TXT

Series

Accession:: GSE160783

ID:: 200160783

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001343216.

Filamentation is Associated with Reduced Pathogenicity of Multiple Non-albicans Candida Species

(Submitter supplied) Candidiasis affects a wide variety of immunocompromised individuals, including HIV/AIDS patients and cancer patients on chemotherapy. Candida albicans, a major human fungal pathogen, accounts for about 50% of all cases, while the remainder are caused by the less pathogenic non-albicans Candida species (NACS). These species are believed to be less pathogenic, in part, because they do not filament as readily or robustly as C. more...

Organism:: Candida parapsilosis; Candida tropicalis

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL21876 GPL18663
16 Samples

Download data: TXT

Series

Accession:: GSE134321

ID:: 200134321

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001141787.

Homo sapiens whole blood infected with Candida spp. (here: Candida tropicalis)

(Submitter supplied) Homo sapiens fresh whole blood was infected with Candida tropicalis. RNA-pool of both species extracted at 0min (control), 15, 30, 60, 120, 240 min. Samples are rRNA depleted. Measurement of Candida tropicalis gene expression.

Organism:: Candida tropicalis; Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL24977
18 Samples

Download data: CSV

Series

Accession:: GSE114178

ID:: 200114178

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001141808.

Homo sapiens whole blood infected with Candida spp.

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Nakaseomyces glabratus; Homo sapiens; Candida tropicalis; Candida albicans; Candida parapsilosis

Type:: Expression profiling by high throughput sequencing

5 related Platforms
75 Samples

Download data

Series

Accession:: GSE114180

ID:: 200114180

PubMed Full text in PMC Similar studies

Select item 2001019999.

Environmental and genetic regulation of white-opaque switching in Candida tropicalis

(Submitter supplied) Phenotypic switching is a strategy by which microbial organisms adapt to environmental changes. The human fungal pathogens, Candida albicans and Candida tropicalis, are closely related species and capable of undergoing morphological transitions. C. albicans primarily exists in human or warm-blooded animals as a commensal, whereas C. tropicalis not only exists as a commensal but also is widely distributed in the environment. more...

Organism:: Candida tropicalis

Type:: Expression profiling by high throughput sequencing

Platform:: GPL21876
6 Samples

Download data: TXT

Series

Accession:: GSE101999

ID:: 200101999

SRA Run Selector

Select item 20008151410.

The gray phenotype in the human fungal pathogen Candida tropicalis

(Submitter supplied) Phenotypic plasticity, the ability to switch between different morphological types, plays critical roles in environmental adaptation, leading to infections, and allowing for sexual reproduction in pathogenic Candida species. Candida tropicalis, which is both an emerging human fungal pathogen and an environmental fungus, can switch between two heritable cell types termed white and opaque. In this study, we report the discovery of a novel phenotype in C. more...

Organism:: Candida tropicalis

Type:: Expression profiling by high throughput sequencing

Platform:: GPL21876
3 Samples

Download data: TXT

Series

Accession:: GSE81514

ID:: 200081514

PubMed Similar studies SRA Run Selector

Select item 20007334011.

Regulation of filamentation in the human fungal pathogen Candida tropicalis

(Submitter supplied) The yeast-filament transition is essential for the virulence of a variety of fungi that are pathogenic to humans. N-acetylglucosamine (GlcNAc), a ubiquitous molecule in both the environment and host, is one of the most potent inducers of filamentation in Candida albicans and thermally dimorphic fungi such as Histoplasma capsulatum and Blastomyces dermatitidis. However, GlcNAc suppresses rather than promotes filamentation in Candida tropicalis, a fungal species that is closely related to C. more...

Organism:: Candida tropicalis MYA-3404

Type:: Expression profiling by high throughput sequencing

Platform:: GPL20946
2 Samples

Download data: TXT

Series

Accession:: GSE73340

ID:: 200073340

PubMed Similar studies SRA Run Selector

Select item 20005263412.

C. tropicalis cells under in vitro biofilm-forming conditions

(Submitter supplied) Transcriptional profiling of a-type wor1 deleted cells and mixed a-type and alpha-type opaque cells under in vitro biofilm-forming conditions. Specifically, they were grown for two days at room temperature in a 12-well poly-styrene plate containing 1 ml of Lee's + Glucose liquid media. Samples were hybridized against a universal mixed reference sample of a-type cells in white and opaque states grown in Spider liquid media.

Organism:: Candida tropicalis

Type:: Expression profiling by array

Platform:: GPL15925
4 Samples

Download data: GPR

Series

Accession:: GSE52634

ID:: 200052634

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20004326713.

C. tropicalis a biofilms of opaque and wor1 overexpressers

(Submitter supplied) Transcriptional profiling of C. tropicalis a cells (CAY1503) in opaque state and overexpressing Wor1 in biofilms hybridized against a universal mixed reference sample of a cells in white and opaque states grown in Spider liquid.

Organism:: Candida tropicalis

Type:: Expression profiling by array

Platform:: GPL15925
4 Samples

Download data: GPR

Series

Accession:: GSE43267

ID:: 200043267

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20004251714.

C. tropicalis a/alpha white, opaque, tdh3-wor, wor1 mutants

(Submitter supplied) Transcriptional profiling of C. tropicalis a/alpha cells (CAY1511) in white state, opaque state, overexpressing Wor1, or wor1 mutants hybridized against a universal mixed reference sample from all 4 states.

Organism:: Candida tropicalis

Type:: Expression profiling by array

Platform:: GPL15925
16 Samples

Download data: GPR

Series

Accession:: GSE42517

ID:: 200042517

Analyze with GEO2R

Select item 20004017915.

Discovery of a phenotypic switch regulating sexual mating in the opportunistic fungal pathogen Candida tropicalis

(Submitter supplied) Sexual reproduction can promote genetic diversity in eukaryotes, and yet many pathogenic fungi have been labeled as obligate asexual species. It is becoming increasingly clear, however, that cryptic sexual programs may exist in some species, and that efficient mating requires the necessary developmental switch to be triggered. In this study we investigate Candida tropicalis, an important human fungal pathogen that has been reported to be asexual. more...

Organism:: Candida tropicalis

Type:: Expression profiling by array

Platform:: GPL15925
8 Samples

Download data: GPR

Series

Accession:: GSE40179

ID:: 200040179

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 10002936416.

Agilent-042593 Candida tropicalis array [Feature Number version]

(Submitter supplied) Microarray for expression profiling of Candida tropicalis Arrays of this design have barcodes that begin with 16042593 or 2542593. Orientation: Features are numbered numbered Left-to-Right, Top-to-Bottom as scanned by an Agilent scanner (barcode on the left, DNA on the back surface, scanned through the glass), matching the FeatureNum output from Agilent's Feature Extraction software. The ID column represents the Agilent Feature Extraction feature number. more...