GEO DataSets

(Submitter supplied) To reveal the correlation between epigenomic diversity and genomic SNVs, we first identified SNPs between T4 with other eleven Trichinella species. In total, we obtained 5,395,250 common SNVs across the twelve Trichinella species.

Organism:

Trichinella nelsoni; Trichinella pseudospiralis; Trichinella murrelli; Trichinella britovi; Trichinella papuae; Trichinella zimbabwensis; Trichinella patagoniensis; Trichinella sp. T8; Trichinella sp. T9; Trichinella spiralis; Trichinella nativa; Trichinella sp. T6

Type:

Other

12 related Platforms

12 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Trichinella britovi; Trichinella sp. T9; Trichinella spiralis; Trichinella nativa; Trichinella sp. T8; Trichinella nelsoni; Trichinella pseudospiralis; Trichinella sp. T6; Trichinella murrelli; Trichinella patagoniensis; Trichinella papuae; Trichinella zimbabwensis

Type:

Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing; Other

24 related Platforms

84 Samples

Download data: TXT

(Submitter supplied) As DNA methylation can modulate gene expression, we then focused our analysis on changes of methylation at the host taxonomic level, that is between encapsulated and non-encapsulated clade, and within non-encapsulated clade, to reveal epigenetic regulation on transcriptomes from Ad and ML stages. By comparing DNA methylation patterns between different host classes of species, we found a fraction of parasitism-related genes under epigenetic regulation, such as G-protein-coupled receptor, DNaseII and ligand-gated chloride channel.

Organism:

Trichinella sp. T8; Trichinella sp. T9; Trichinella sp. T6; Trichinella spiralis; Trichinella nativa; Trichinella nelsoni; Trichinella pseudospiralis; Trichinella britovi; Trichinella murrelli; Trichinella papuae; Trichinella zimbabwensis; Trichinella patagoniensis

Type:

Expression profiling by high throughput sequencing

12 related Platforms

36 Samples

Download data: TXT

(Submitter supplied) As the most studied type of epigenetic modifications found in many taxa, DNA methylation has been confirmed to play a crucial role in transposon silencing, transcriptional regulation and thus phenotypic variation, as well as rapid adaption to changing environments. To fully understand the methylome variation in Trichinella, here, we report 12 single-base resolution methylomes of three life stages using WGBS. more...

Organism:

Trichinella spiralis; Trichinella nativa; Trichinella zimbabwensis; Trichinella nelsoni; Trichinella pseudospiralis; Trichinella britovi; Trichinella murrelli; Trichinella patagoniensis; Trichinella sp. T8; Trichinella sp. T9; Trichinella papuae; Trichinella sp. T6

Type:

Methylation profiling by high throughput sequencing

12 related Platforms

36 Samples

Download data: TXT

(Submitter supplied) DNA methylation in basal nematodes analysed by bisulfite sequencing

Organism:

Romanomermis culicivorax; Trichuris muris; Plectus sambesii; Trichinella spiralis

Type:

Methylation profiling by high throughput sequencing

4 related Platforms

4 Samples

Download data: BED

(Submitter supplied) Comparison of small RNA profiles across nematode evolution

Organism:

Caenorhabditis elegans; Trichinella spiralis; Odontophora rectangula; Romanomermis culicivorax; Nippostrongylus brasiliensis; Hypsibius dujardini; Brugia malayi; Globodera pallida; Pristionchus pacificus; Enoplus brevis; Paragordius varius

Type:

Non-coding RNA profiling by high throughput sequencing

11 related Platforms

22 Samples

Download data: FA, FASTA

(Submitter supplied) Trichinellosis of human and other mammals was caused through the ingestion of the parasite，Trichinella spiralis，contaminated meat. It is a typical zoonotic disease that affects more than 10 million people world-wide. Parasites of Trichinella genus are unique intracellular pathogens. Adult Trichinella parasites directly release newborn larvae which invade striated muscle cells and causes diseases. In this study, we profiled the global transcriptome in the three developmental stages of T. more...

Organism:

Trichinella spiralis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL15773

3 Samples

Download data: TXT

(Submitter supplied) We present the first study to confirm the existence of DNA methylation in the parasitic nematode Trichinella spiralis, and we characterize the methylomes of the three life-cycle stages of this food-borne infectious human pathogen. We observe a drastic increase in DNA methylation during the transition from the new born to mature stage, and we further identify parasitism-related genes that show changes in DNA methylation status between life cycle stages. more...

Organism:

Trichinella spiralis

Type:

Methylation profiling by high throughput sequencing; Expression profiling by high throughput sequencing

Platforms:

GPL15806 GPL15773

6 Samples

Download data: TXT