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Series GSE110474 Query DataSets for GSE110474
Status Public on Feb 04, 2021
Title Expression data from intestine samples of mice lacking intestinal Pcyt1a, which encodes an enzyme that regulates phosphatidylcholine synthesis.
Organism Mus musculus
Experiment type Expression profiling by array
Summary Phosphatidylcholine is a membrane lipid. To determine its role in the intestine, we deleted the gene that produces this lipid specificallly in intestinal epithelial cells and conducted expression analysis.
We used microarray analysis to determine changes in gene expression that occur in the absence of intestinal phosphatidylcholine synthesis.
Overall design Mice lacking intestinal Pcyt1a and their Pcyt1a-positive controls were fasted overnight and re-fed a high fat diet. We then extracted RNA and hybridized to Affymetrix microarrays. Samples were collected from the geometric middle of the small intestine (jejunum).
Contributor(s) Jacobs RL, Kennelly JP
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Submission date Feb 12, 2018
Last update date Feb 07, 2021
Contact name René L Jacobs
Organization name University of Alberta
Department Agriculture, Food and Nutritional Science; Biochemistry
Lab Jacobs Lab
Street address Li Ka Shing Centre for Health Research
City Edmonton
State/province Alberta
ZIP/Postal code T6G2E1
Country Canada
Platforms (1)
GPL16570 [MoGene-2_0-st] Affymetrix Mouse Gene 2.0 ST Array [transcript (gene) version]
Samples (10)
GSM2991900 Fed Knockout 1
GSM2991901 Fed Knockout 2
GSM2991902 Fed Knockout 3
BioProject PRJNA433833

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Supplementary file Size Download File type/resource
GSE110474_RAW.tar 89.5 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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