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Series GSE21583 Query DataSets for GSE21583
Status Public on Aug 25, 2010
Title Effects of ACE2 on BMPR2 mutation-mediated defects in gene expression
Organism Mus musculus
Experiment type Expression profiling by array
Summary BMPR2 mutation causes pulmonary arterial hypertension (PAH); ACE2 treatment can resolve established BMPR2-mediated PAH. The purpose of this study was to uncover the molecular mechanism behind this.
Overall design Four groups: +/- ACE2 and +/- BMPR2 transgene, two arrays each, each array a pool of three animals.
Contributor(s) Johnson J, West J
Citation(s) 22180660
Submission date Apr 28, 2010
Last update date Feb 11, 2019
Contact name James West
Organization name Vanderbilt University
Department Medicine
Lab Pulmonary
Street address 4200 E 9TH Ave, Box B133
City Nashville
State/province TN
ZIP/Postal code 37201
Country USA
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (8)
GSM538875 Control mouse lung (1)
GSM538876 Control mouse lung (2)
GSM538877 Control mouse + chronic ACE2 lung (1)
BioProject PRJNA127021

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE21583_RAW.tar 32.1 Mb (http)(custom) TAR (of CEL, CHP)
Processed data included within Sample table
Processed data provided as supplementary file

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