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Series GSE5 Query DataSets for GSE5
Status Public on Jul 24, 2001
Title Global profile of germline gene expression in C. elegans
Organism Caenorhabditis elegans
Experiment type Expression profiling by array
Summary We used DNA microarrays to profile gene expression patterns in the C. elegans germline and identified 1416 germline-enriched transcripts that define three groups. The sperm-enriched group contains an unusually large number of protein kinases and phosphatases. The oocyte-enriched group includes potentially new components of embryonic signaling pathways. The germline-intrinsic group, defined as genes expressed similarly in germlines making only sperm or only oocytes, contains a family of piwi-related genes that may be important for stem cell proliferation. Finally, examination of the chromosomal location of germline transcripts revealed that sperm-enriched and germline-intrinsic genes are nearly absent from the X chromosome, but oocyte-enriched genes are not.
This research has been described more fully in Reinke V et al.(2000) Mol Cell 6:605-16
Keywords: other
Contributor(s) Reinke V, Smith HE, Nance J, Wang J, Van Doren C, Begley R, Jones SJ, Davis EB, Scherer S, Ward S, Kim SK
Citation(s) 11030340
Submission date Jul 24, 2001
Last update date Feb 23, 2012
Organization Stanford Microarray Database (SMD)
Phone 650-498-6012
Department Stanford University, School of Medicine
Street address 300 Pasteur Drive
City Stanford
State/province CA
ZIP/Postal code 94305
Country USA
Platforms (1)
GPL14 ce_rosetta
Samples (34)
GSM436 fem-3(q23) (red, channel 2) vs. fem-1(hc17) (green, channel 1)
GSM437 fem-3(q23) (red, channel 2) vs. fem-1(hc17) (green, channel 1)- repeat #1
GSM438 vjr N2 mixed control (red, channel 2) vs N2-3 T4 (green, channel 1)
BioProject PRJNA85207

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