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Recurrent Childhood Cerebellar Astrocytoma

MedGen UID:
137885
•Concept ID:
C0338338
•
Neoplastic Process
Synonyms: Recurrent Childhood Astrocytoma of Cerebellum; Recurrent Childhood Astrocytoma of the Cerebellum; Recurrent Pediatric Astrocytoma of Cerebellum; Recurrent Pediatric Astrocytoma of the Cerebellum; Recurrent Pediatric Cerebellar Astrocytoma; Relapsed Childhood Astrocytoma of Cerebellum; Relapsed Childhood Astrocytoma of the Cerebellum; Relapsed Childhood Cerebellar Astrocytoma; Relapsed Pediatric Astrocytoma of Cerebellum; Relapsed Pediatric Astrocytoma of the Cerebellum; Relapsed Pediatric Cerebellar Astrocytoma

Definition

Regrowth of benign and malignant childhood cerebellar astrocytomas that have previously been subjected to surgical resection and less frequently other forms of therapy such as radiation or chemotherapy. Recurrence of benign tumors (e.g., (pilocytic astrocytoma) may respond to a second surgical procedure. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Childhood Cerebellar Astrocytoma

Professional guidelines

PubMed

Magnetic Resonance Imaging in the Contemporary Management of Medulloblastoma: Current and Emerging Applications.
Dasgupta A, Maitre M, Pungavkar S, Gupta T
Methods Mol Biol 2022;2423:187-214. doi: 10.1007/978-1-0716-1952-0_18. PMID: 34978700

Recent clinical studies

Etiology

Magnetic Resonance Imaging in the Contemporary Management of Medulloblastoma: Current and Emerging Applications.
Dasgupta A, Maitre M, Pungavkar S, Gupta T
Methods Mol Biol 2022;2423:187-214. doi: 10.1007/978-1-0716-1952-0_18. PMID: 34978700
The benefit of surveillance imaging for paediatric cerebellar pilocytic astrocytoma.
McAuley E, Brophy H, Hayden J, Pettorini B, Parks C, Avula S, Mallucci C, Pizer B
Childs Nerv Syst 2019 May;35(5):801-805. Epub 2019 Feb 15 doi: 10.1007/s00381-019-04078-3. PMID: 30770993
Surveillance imaging strategies following surgery and/or radiotherapy for childhood cerebellar low-grade astrocytoma.
Saunders DE, Phipps KP, Wade AM, Hayward RD
J Neurosurg 2005 Mar;102(2 Suppl):172-8. doi: 10.3171/jns.2005.102.2.0172. PMID: 16156227
Cerebellar astrocytoma: report of 13 cases aged over 20 years and review of the literature.
Hassounah M, Siqueira EB, Haider A, Gray A
Br J Neurosurg 1996 Aug;10(4):365-71. doi: 10.1080/02688699647285. PMID: 8864501
Cerebellar astrocytoma of childhood: long-term follow-up.
Sgouros S, Fineron PW, Hockley AD
Childs Nerv Syst 1995 Feb;11(2):89-96. doi: 10.1007/BF00303812. PMID: 7758018

Diagnosis

Pediatric-Like Brain Tumors in Adults.
Dias SF, Richards O, Elliot M, Chumas P
Adv Tech Stand Neurosurg 2024;50:147-183. doi: 10.1007/978-3-031-53578-9_5. PMID: 38592530
Magnetic Resonance Imaging in the Contemporary Management of Medulloblastoma: Current and Emerging Applications.
Dasgupta A, Maitre M, Pungavkar S, Gupta T
Methods Mol Biol 2022;2423:187-214. doi: 10.1007/978-1-0716-1952-0_18. PMID: 34978700
The benefit of surveillance imaging for paediatric cerebellar pilocytic astrocytoma.
McAuley E, Brophy H, Hayden J, Pettorini B, Parks C, Avula S, Mallucci C, Pizer B
Childs Nerv Syst 2019 May;35(5):801-805. Epub 2019 Feb 15 doi: 10.1007/s00381-019-04078-3. PMID: 30770993
Surveillance imaging strategies following surgery and/or radiotherapy for childhood cerebellar low-grade astrocytoma.
Saunders DE, Phipps KP, Wade AM, Hayward RD
J Neurosurg 2005 Mar;102(2 Suppl):172-8. doi: 10.3171/jns.2005.102.2.0172. PMID: 16156227
Leptomeningeal dissemination of pilocytic astrocytoma at diagnosis in childhood: two cases report.
Figueiredo EG, Matushita H, Machado AG, Plese JP, Rosemberg S, Marino R Jr
Arq Neuropsiquiatr 2003 Sep;61(3B):842-7. Epub 2003 Oct 28 doi: 10.1590/s0004-282x2003000500025. PMID: 14595493

Therapy

Proton beam therapy in a patient with secondary glioblastoma (32 years after postoperative irradiation of medulloblastoma): case report and literature review.
Jiwei B, Abulimiti M, Yonglong J, Jie W, Shuyan Z, Chao L, Zishen W, Wei W, Yinuo L, Weiwei W, Lu Y, Shimizu S
Radiat Oncol 2024 Oct 5;19(1):136. doi: 10.1186/s13014-024-02515-5. PMID: 39369243Free PMC Article
Cisplatin, ara-C and etoposide (PAE) in the treatment of recurrent childhood brain tumors.
Corden BJ, Strauss LC, Killmond T, Carson BS, Wharam MD, Kumar AJ, Piantadosi S, Robb PA, Phillips PC
J Neurooncol 1991 Aug;11(1):57-63. doi: 10.1007/BF00166998. PMID: 1919647
Carboplatin in childhood brain tumors. A Children's Cancer Study Group Phase II trial.
Gaynon PS, Ettinger LJ, Baum ES, Siegel SE, Krailo MD, Hammond GD
Cancer 1990 Dec 15;66(12):2465-9. doi: 10.1002/1097-0142(19901215)66:12<2465::aid-cncr2820661204>3.0.co;2-n. PMID: 2249186
Malignant supratentorial gliomas in childhood.
Prados M, Levin V
Pediatr Neurosci 1987;13(3):144-51. doi: 10.1159/000120320. PMID: 3331428
Rhabdomyosarcoma of the ear in childhood. A report from the Intergroup Rhabdomyosarcoma Study-I.
Raney RB Jr, Lawrence W Jr, Maurer HM, Lindberg RD, Newton WA Jr, Ragab AH, Tefft M, Foulkes MA
Cancer 1983 Jun 15;51(12):2356-61. doi: 10.1002/1097-0142(19830615)51:12<2356::aid-cncr2820511232>3.0.co;2-l. PMID: 6342748

Prognosis

Magnetic Resonance Imaging in the Contemporary Management of Medulloblastoma: Current and Emerging Applications.
Dasgupta A, Maitre M, Pungavkar S, Gupta T
Methods Mol Biol 2022;2423:187-214. doi: 10.1007/978-1-0716-1952-0_18. PMID: 34978700
The benefit of surveillance imaging for paediatric cerebellar pilocytic astrocytoma.
McAuley E, Brophy H, Hayden J, Pettorini B, Parks C, Avula S, Mallucci C, Pizer B
Childs Nerv Syst 2019 May;35(5):801-805. Epub 2019 Feb 15 doi: 10.1007/s00381-019-04078-3. PMID: 30770993
Brainstem astrocytoma as a neuro-Behçet's disease mimic.
Manasson J, Howard J, Nowatzky J
BMJ Case Rep 2018 Dec 7;11(1) doi: 10.1136/bcr-2018-226945. PMID: 30567204Free PMC Article
Surveillance imaging strategies following surgery and/or radiotherapy for childhood cerebellar low-grade astrocytoma.
Saunders DE, Phipps KP, Wade AM, Hayward RD
J Neurosurg 2005 Mar;102(2 Suppl):172-8. doi: 10.3171/jns.2005.102.2.0172. PMID: 16156227
Cerebellar astrocytoma: report of 13 cases aged over 20 years and review of the literature.
Hassounah M, Siqueira EB, Haider A, Gray A
Br J Neurosurg 1996 Aug;10(4):365-71. doi: 10.1080/02688699647285. PMID: 8864501

Clinical prediction guides

Magnetic Resonance Imaging in the Contemporary Management of Medulloblastoma: Current and Emerging Applications.
Dasgupta A, Maitre M, Pungavkar S, Gupta T
Methods Mol Biol 2022;2423:187-214. doi: 10.1007/978-1-0716-1952-0_18. PMID: 34978700
CORNEAL NEUROTIZATION IN A PATIENT WITH SEVERE NEUROTROPHIC KERATOPATHY. CASE REPORT.
Rusňák Š, Hecová L, Štěpánek D, Sobotová M
Cesk Slov Oftalmol 2021 Winter;77(3):146–152. doi: 10.31348/2021/17. PMID: 35130706
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma.
Jones DT, Hutter B, Jäger N, Korshunov A, Kool M, Warnatz HJ, Zichner T, Lambert SR, Ryzhova M, Quang DA, Fontebasso AM, Stütz AM, Hutter S, Zuckermann M, Sturm D, Gronych J, Lasitschka B, Schmidt S, Seker-Cin H, Witt H, Sultan M, Ralser M, Northcott PA, Hovestadt V, Bender S, Pfaff E, Stark S, Faury D, Schwartzentruber J, Majewski J, Weber UD, Zapatka M, Raeder B, Schlesner M, Worth CL, Bartholomae CC, von Kalle C, Imbusch CD, Radomski S, Lawerenz C, van Sluis P, Koster J, Volckmann R, Versteeg R, Lehrach H, Monoranu C, Winkler B, Unterberg A, Herold-Mende C, Milde T, Kulozik AE, Ebinger M, Schuhmann MU, Cho YJ, Pomeroy SL, von Deimling A, Witt O, Taylor MD, Wolf S, Karajannis MA, Eberhart CG, Scheurlen W, Hasselblatt M, Ligon KL, Kieran MW, Korbel JO, Yaspo ML, Brors B, Felsberg J, Reifenberger G, Collins VP, Jabado N, Eils R, Lichter P, Pfister SM; International Cancer Genome Consortium PedBrain Tumor Project
Nat Genet 2013 Aug;45(8):927-32. Epub 2013 Jun 30 doi: 10.1038/ng.2682. PMID: 23817572Free PMC Article
Chromosomal characteristics of childhood brain tumors.
Bigner SH, McLendon RE, Fuchs H, McKeever PE, Friedman HS
Cancer Genet Cytogenet 1997 Sep;97(2):125-34. doi: 10.1016/s0165-4608(96)00404-9. PMID: 9283596
Malignant transformation of benign cerebellar astrocytoma.
Schwartz AM, Ghatak NR
Cancer 1990 Jan 15;65(2):333-6. doi: 10.1002/1097-0142(19900115)65:2<333::aid-cncr2820650225>3.0.co;2-3. PMID: 2403835

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