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Brain astrocytoma

MedGen UID:
811330
•Concept ID:
C3695127
•
Neoplastic Process
Synonyms: Astrocytic tumor of brain; astrocytoma (excluding glioblastoma) of brain; Astrocytoma of brain; Brain Astrocytoma; brain astrocytoma; brain astrocytoma (excluding glioblastoma)
SNOMED CT: Astrocytic tumor of brain (254938000); Astrocytoma of brain (254938000)
 
Monarch Initiative: MONDO:0021631

Definition

An astrocytoma that occurs in the brain. [from NCI]

Professional guidelines

PubMed

Treatment patterns of glioma in Pakistan: An epidemiological perspective.
Bajwa MH, Khalid MU, Shah MM, Shamim MS, Laghari AA, Akhunzada NZ, Anis SB, Raghib MF; Pakistan Brain Tumour Consortium, Siddiqi S, Enam SA; Pakistan Brain Tumour Consortium Group Names
J Pak Med Assoc 2022 Nov;72(Suppl 4)(11):S34-S39. doi: 10.47391/JPMA.11-S4-AKUB05. PMID: 36591625
Increased frequency of rapid acetylator genotypes in patients with brain astrocytoma and meningioma.
Olivera M, Martínez C, Molina JA, Alonso-Navarro H, Jiménez-Jiménez FJ, García-Martín E, Benítez J, Agúndez JA
Acta Neurol Scand 2006 May;113(5):322-6. doi: 10.1111/j.1600-0404.2006.00590.x. PMID: 16629768
Recent concepts in the conservative treatment of intracranial tumours in children.
Bloom HJ
Acta Neurochir (Wien) 1979;50(1-2):103-16. doi: 10.1007/BF01813555. PMID: 229698

Recent clinical studies

Etiology

Risk factor analysis and nomogram establishment and verification of brain astrocytoma patients based on SEER database.
Wang R, Cui J, Diao Y, Jin C, Chen Y, Lv X, Li X
Sci Rep 2023 May 12;13(1):7754. doi: 10.1038/s41598-023-33537-w. PMID: 37173353Free PMC Article
Expression and functional significance of ezrin in human brain astrocytoma.
Mao J, Yuan XR, Xu SS, Jiang XC, Zhao XT
Cell Biochem Biophys 2013;67(3):1507-11. doi: 10.1007/s12013-013-9653-1. PMID: 23712870
Two common nonsynonymous paraoxonase 1 (PON1) gene polymorphisms and brain astrocytoma and meningioma.
Martínez C, Molina JA, Alonso-Navarro H, Jiménez-Jiménez FJ, Agúndez JA, García-Martín E
BMC Neurol 2010 Aug 19;10:71. doi: 10.1186/1471-2377-10-71. PMID: 20723250Free PMC Article
Association of preoperative depression and survival after resection of malignant brain astrocytoma.
Gathinji M, McGirt MJ, Attenello FJ, Chaichana KL, Than K, Olivi A, Weingart JD, Brem H, Quinones-Hinojosa A
Surg Neurol 2009 Mar;71(3):299-303, discussion 303. Epub 2008 Sep 11 doi: 10.1016/j.surneu.2008.07.016. PMID: 18786716
Increased frequency of rapid acetylator genotypes in patients with brain astrocytoma and meningioma.
Olivera M, Martínez C, Molina JA, Alonso-Navarro H, Jiménez-Jiménez FJ, García-Martín E, Benítez J, Agúndez JA
Acta Neurol Scand 2006 May;113(5):322-6. doi: 10.1111/j.1600-0404.2006.00590.x. PMID: 16629768

Diagnosis

Risk factor analysis and nomogram establishment and verification of brain astrocytoma patients based on SEER database.
Wang R, Cui J, Diao Y, Jin C, Chen Y, Lv X, Li X
Sci Rep 2023 May 12;13(1):7754. doi: 10.1038/s41598-023-33537-w. PMID: 37173353Free PMC Article
Brain astrocytoma misdiagnosed as anti-NMDAR encephalitis: a case report.
Lu J, Zhang JH, Miao AL, Yin JX, Zhu DL, Lin XJ, Chen DW, Shi JP
BMC Neurol 2019 Aug 28;19(1):210. doi: 10.1186/s12883-019-1436-x. PMID: 31462223Free PMC Article
Potential Utility of Visually AcceSAble Rembrandt Images Assessment in Brain Astrocytoma Grading.
Yu J, Wang M, Song J, Huang D, Hong X
J Comput Assist Tomogr 2016 Mar-Apr;40(2):301-6. doi: 10.1097/RCT.0000000000000352. PMID: 26978002
Expression of neonatal Nav1.5 in human brain astrocytoma and its effect on proliferation, invasion and apoptosis of astrocytoma cells.
Xing D, Wang J, Ou S, Wang Y, Qiu B, Ding D, Guo F, Gao Q
Oncol Rep 2014 Jun;31(6):2692-700. Epub 2014 Apr 17 doi: 10.3892/or.2014.3143. PMID: 24756536
Association of preoperative depression and survival after resection of malignant brain astrocytoma.
Gathinji M, McGirt MJ, Attenello FJ, Chaichana KL, Than K, Olivi A, Weingart JD, Brem H, Quinones-Hinojosa A
Surg Neurol 2009 Mar;71(3):299-303, discussion 303. Epub 2008 Sep 11 doi: 10.1016/j.surneu.2008.07.016. PMID: 18786716

Therapy

Fluoxetine enhances the antitumor effect of olfactory ensheathing cell-thymidine kinase/ganciclovir gene therapy in human glioblastoma multiforme cells through upregulation of Connexin43 levels.
Hosseindoost S, Dehpour AR, Dehghan S, Javadi SAH, Arjmand B, Fallah A, Hadjighassem M
Drug Dev Res 2023 Dec;84(8):1739-1750. Epub 2023 Sep 28 doi: 10.1002/ddr.22119. PMID: 37769152
Risk factor analysis and nomogram establishment and verification of brain astrocytoma patients based on SEER database.
Wang R, Cui J, Diao Y, Jin C, Chen Y, Lv X, Li X
Sci Rep 2023 May 12;13(1):7754. doi: 10.1038/s41598-023-33537-w. PMID: 37173353Free PMC Article
Targeted Delivery of Functionalized Upconversion Nanoparticles for Externally Triggered Photothermal/Photodynamic Therapies of Brain Glioblastoma.
Tsai YC, Vijayaraghavan P, Chiang WH, Chen HH, Liu TI, Shen MY, Omoto A, Kamimura M, Soga K, Chiu HC
Theranostics 2018;8(5):1435-1448. Epub 2018 Feb 4 doi: 10.7150/thno.22482. PMID: 29507632Free PMC Article
Tumortropic adipose-derived stem cells carrying smart nanotherapeutics for targeted delivery and dual-modality therapy of orthotopic glioblastoma.
Huang WC, Lu IL, Chiang WH, Lin YW, Tsai YC, Chen HH, Chang CW, Chiang CS, Chiu HC
J Control Release 2017 May 28;254:119-130. Epub 2017 Mar 21 doi: 10.1016/j.jconrel.2017.03.035. PMID: 28336375
PET imaging of brain astrocytoma with 1-11C-acetate.
Liu RS, Chang CP, Chu LS, Chu YK, Hsieh HJ, Chang CW, Yang BH, Yen SH, Huang MC, Liao SQ, Yeh SH
Eur J Nucl Med Mol Imaging 2006 Apr;33(4):420-7. Epub 2006 Jan 11 doi: 10.1007/s00259-005-0023-0. PMID: 16404596

Prognosis

Risk factor analysis and nomogram establishment and verification of brain astrocytoma patients based on SEER database.
Wang R, Cui J, Diao Y, Jin C, Chen Y, Lv X, Li X
Sci Rep 2023 May 12;13(1):7754. doi: 10.1038/s41598-023-33537-w. PMID: 37173353Free PMC Article
Potential Utility of Visually AcceSAble Rembrandt Images Assessment in Brain Astrocytoma Grading.
Yu J, Wang M, Song J, Huang D, Hong X
J Comput Assist Tomogr 2016 Mar-Apr;40(2):301-6. doi: 10.1097/RCT.0000000000000352. PMID: 26978002
Expression and functional significance of ezrin in human brain astrocytoma.
Mao J, Yuan XR, Xu SS, Jiang XC, Zhao XT
Cell Biochem Biophys 2013;67(3):1507-11. doi: 10.1007/s12013-013-9653-1. PMID: 23712870
Peritumoral edema and karyometric variables in astrocytoma of the brain.
Kostic A, Mihailovic D, Veselinovic S, Tasic G, Radulovic D, Stefanovic I
J BUON 2007 Apr-Jun;12(2):239-43. PMID: 17600879
Human astrocytoma U251 RNA and genomic brain glycogen phosphorylase sequences.
Roscoe JA, Gorin FA, Tait RC
Brain Res Mol Brain Res 1991 Jun;10(3):273-5. doi: 10.1016/0169-328x(91)90071-5. PMID: 1715969

Clinical prediction guides

Risk factor analysis and nomogram establishment and verification of brain astrocytoma patients based on SEER database.
Wang R, Cui J, Diao Y, Jin C, Chen Y, Lv X, Li X
Sci Rep 2023 May 12;13(1):7754. doi: 10.1038/s41598-023-33537-w. PMID: 37173353Free PMC Article
Cyclotides Chemosensitize Glioblastoma Cells to Temozolomide.
Gerlach SL, Dunlop RA, Metcalf JS, Banack SA, Cox PA
J Nat Prod 2022 Jan 28;85(1):34-46. Epub 2022 Jan 19 doi: 10.1021/acs.jnatprod.1c00595. PMID: 35044783
Expression of neonatal Nav1.5 in human brain astrocytoma and its effect on proliferation, invasion and apoptosis of astrocytoma cells.
Xing D, Wang J, Ou S, Wang Y, Qiu B, Ding D, Guo F, Gao Q
Oncol Rep 2014 Jun;31(6):2692-700. Epub 2014 Apr 17 doi: 10.3892/or.2014.3143. PMID: 24756536
Neuritin expression and its relation with proliferation, apoptosis, and angiogenesis in human astrocytoma.
Zhang L, Zhao Y, Wang CG, Fei Z, Wang Y, Li L, Li L, Zhen HN
Med Oncol 2011 Sep;28(3):907-12. Epub 2010 Apr 20 doi: 10.1007/s12032-010-9537-9. PMID: 20405246
Increased frequency of rapid acetylator genotypes in patients with brain astrocytoma and meningioma.
Olivera M, Martínez C, Molina JA, Alonso-Navarro H, Jiménez-Jiménez FJ, García-Martín E, Benítez J, Agúndez JA
Acta Neurol Scand 2006 May;113(5):322-6. doi: 10.1111/j.1600-0404.2006.00590.x. PMID: 16629768

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