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Dyssynergia

MedGen UID:
13945
Concept ID:
C0004134
Sign or Symptom
Synonym: Ataxia
SNOMED CT: Ataxia (loss of muscle coordination) (20262006); Ataxia (20262006); Dyssynergia (39384006)
 
HPO: HP:0010867

Definition

A type of ataxia characterized by the impairment of the ability to smoothly perform the elements of a voluntary movement in the appropriate order and speed. With dyssynergia, a voluntary movement appears broken down into its component parts. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDyssynergia

Professional guidelines

PubMed

Moshiree B, Drossman D, Shaukat A
Gastroenterology 2023 Sep;165(3):791-800.e3. Epub 2023 Jul 13 doi: 10.1053/j.gastro.2023.04.039. PMID: 37452811
Carrington EV, Heinrich H, Knowles CH, Fox M, Rao S, Altomare DF, Bharucha AE, Burgell R, Chey WD, Chiarioni G, Dinning P, Emmanuel A, Farouk R, Felt-Bersma RJF, Jung KW, Lembo A, Malcolm A, Mittal RK, Mion F, Myung SJ, O'Connell PR, Pehl C, Remes-Troche JM, Reveille RM, Vaizey CJ, Vitton V, Whitehead WE, Wong RK, Scott SM; All members of the International Anorectal Physiology Working Group
Neurogastroenterol Motil 2020 Jan;32(1):e13679. Epub 2019 Aug 12 doi: 10.1111/nmo.13679. PMID: 31407463Free PMC Article
Rao SS
Gastroenterol Clin North Am 2003 Jun;32(2):659-83. doi: 10.1016/s0889-8553(03)00026-8. PMID: 12858610

Recent clinical studies

Etiology

Moshiree B, Drossman D, Shaukat A
Gastroenterology 2023 Sep;165(3):791-800.e3. Epub 2023 Jul 13 doi: 10.1053/j.gastro.2023.04.039. PMID: 37452811
Carrington EV, Heinrich H, Knowles CH, Fox M, Rao S, Altomare DF, Bharucha AE, Burgell R, Chey WD, Chiarioni G, Dinning P, Emmanuel A, Farouk R, Felt-Bersma RJF, Jung KW, Lembo A, Malcolm A, Mittal RK, Mion F, Myung SJ, O'Connell PR, Pehl C, Remes-Troche JM, Reveille RM, Vaizey CJ, Vitton V, Whitehead WE, Wong RK, Scott SM; All members of the International Anorectal Physiology Working Group
Neurogastroenterol Motil 2020 Jan;32(1):e13679. Epub 2019 Aug 12 doi: 10.1111/nmo.13679. PMID: 31407463Free PMC Article
Hamid R, Averbeck MA, Chiang H, Garcia A, Al Mousa RT, Oh SJ, Patel A, Plata M, Del Popolo G
World J Urol 2018 Oct;36(10):1517-1527. Epub 2018 May 11 doi: 10.1007/s00345-018-2301-z. PMID: 29752515
Amarenco G, Sheikh Ismaël S, Chesnel C, Charlanes A, LE Breton F
Eur J Phys Rehabil Med 2017 Dec;53(6):975-980. Epub 2017 Oct 25 doi: 10.23736/S1973-9087.17.04992-9. PMID: 29072046
Stocchi F, Torti M
Int Rev Neurobiol 2017;134:811-826. Epub 2017 Jul 13 doi: 10.1016/bs.irn.2017.06.003. PMID: 28805584

Diagnosis

Moshiree B, Drossman D, Shaukat A
Gastroenterology 2023 Sep;165(3):791-800.e3. Epub 2023 Jul 13 doi: 10.1053/j.gastro.2023.04.039. PMID: 37452811
Damianos JA, Tomar SK, Azpiroz F, Barba E
Am J Gastroenterol 2023 Jan 1;118(1):41-45. Epub 2022 Sep 30 doi: 10.14309/ajg.0000000000002044. PMID: 36191283Free PMC Article
Felt-Bersma RJF
Curr Opin Gastroenterol 2021 Jan;37(1):59-65. doi: 10.1097/MOG.0000000000000689. PMID: 33060396
Amarenco G, Sheikh Ismaël S, Chesnel C, Charlanes A, LE Breton F
Eur J Phys Rehabil Med 2017 Dec;53(6):975-980. Epub 2017 Oct 25 doi: 10.23736/S1973-9087.17.04992-9. PMID: 29072046
Stocchi F, Torti M
Int Rev Neurobiol 2017;134:811-826. Epub 2017 Jul 13 doi: 10.1016/bs.irn.2017.06.003. PMID: 28805584

Therapy

Santucci NR, Chogle A, Leiby A, Mascarenhas M, Borlack RE, Lee A, Perez M, Russell A, Yeh AM
Complement Ther Med 2021 Jun;59:102711. Epub 2021 Mar 15 doi: 10.1016/j.ctim.2021.102711. PMID: 33737146
Ferrucci R, Bocci T, Cortese F, Ruggiero F, Priori A
Curr Neuropharmacol 2019;17(1):14-20. doi: 10.2174/1570159X15666171114142422. PMID: 29141551Free PMC Article
Stocchi F, Torti M
Int Rev Neurobiol 2017;134:811-826. Epub 2017 Jul 13 doi: 10.1016/bs.irn.2017.06.003. PMID: 28805584
King A, Quirouet A, Moore CK
Cleve Clin J Med 2015 Jul;82(7):456-64. doi: 10.3949/ccjm.82a.13166. PMID: 26185945
Rossi M, Merello M, Perez-Lloret S
Expert Opin Pharmacother 2015 Mar;16(4):547-57. Epub 2014 Dec 25 doi: 10.1517/14656566.2015.997211. PMID: 25539892

Prognosis

Quigley EMM
Semin Neurol 2023 Aug;43(4):562-571. Epub 2023 Aug 14 doi: 10.1055/s-0043-1771457. PMID: 37579786
Panicker JN, Fowler CJ
Handb Clin Neurol 2015;130:371-81. doi: 10.1016/B978-0-444-63247-0.00021-3. PMID: 26003255
Badlani GH
J Endourol 1997 Dec;11(6):473-5. doi: 10.1089/end.1997.11.473. PMID: 9440859
Bukowski TP, Lewis AG, Reeves D, Wacksman J, Sheldon CA
J Urol 1995 Aug;154(2 Pt 2):762-5. PMID: 7609173
Wheeler JS Jr, Culkin DJ, Walter JS, Flanigan RC
Urology 1990 May;35(5):428-32. doi: 10.1016/0090-4295(90)80086-3. PMID: 1970915

Clinical prediction guides

Moshiree B, Drossman D, Shaukat A
Gastroenterology 2023 Sep;165(3):791-800.e3. Epub 2023 Jul 13 doi: 10.1053/j.gastro.2023.04.039. PMID: 37452811
Cariati M, Chiarello MM, Cannistra' M, Lerose MA, Brisinda G
Handb Exp Pharmacol 2021;263:185-226. doi: 10.1007/164_2019_326. PMID: 32072269
Borg M
Neurophysiol Clin 2006 Sep-Dec;36(5-6):309-18. Epub 2007 Jan 17 doi: 10.1016/j.neucli.2006.12.006. PMID: 17336775
Yalla SV, Blunt KJ, Fam BA, Constantinople NL, Gittes RF
J Urol 1977 Dec;118(6):1026-9. doi: 10.1016/s0022-5347(17)58286-5. PMID: 926242
Fantl JA, Hurt WG, Dunn LJ
Am J Obstet Gynecol 1977 Oct 1;129(3):299-303. doi: 10.1016/0002-9378(77)90787-6. PMID: 561544

Recent systematic reviews

Chaichanavichkij P, Vollebregt PF, Scott SM, Knowles CH
Colorectal Dis 2020 Dec;22(12):1832-1841. Epub 2020 Jun 11 doi: 10.1111/codi.15120. PMID: 32403161
Goel S, Pierce H, Pain K, Christos P, Dmochowski R, Chughtai B
Urology 2020 Jun;140:7-13. Epub 2020 Mar 19 doi: 10.1016/j.urology.2020.03.007. PMID: 32197987
Stoffel JT
Urol Clin North Am 2017 Aug;44(3):429-439. doi: 10.1016/j.ucl.2017.04.009. PMID: 28716323
Whitehead WE, Palsson OS, Simrén M
Neurogastroenterol Motil 2016 Jun;28(6):783-92. doi: 10.1111/nmo.12852. PMID: 27214096
Liu N, Zhou M, Biering-Sørensen F, Krassioukov AV
Spinal Cord 2015 Jul;53(7):500-9. Epub 2015 Mar 24 doi: 10.1038/sc.2015.39. PMID: 25800696

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