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Recurrent Primary Cutaneous Lymphoma

MedGen UID:: 1637457
•Concept ID:: C4684885
•: Neoplastic Process

Definition

The reemergence of primary cutaneous lymphoma after a period of remission. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVRecurrent Primary Cutaneous Lymphoma

Hematopoietic and Lymphoid System Disorder
- Hematologic disorder
  - Hematopoietic and lymphoid cell neoplasm
    - Cutaneous Hematopoietic and Lymphoid Cell Neoplasm
      - Cutaneous Lymphoma
        Primary cutaneous lymphoma
        Recurrent Primary Cutaneous Lymphoma
        Recurrent Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type
        Recurrent Primary Cutaneous T-Cell Non-Hodgkin Lymphoma
        Recurrent Mycosis Fungoides
        Recurrent Transformed Mycosis Fungoides
        Recurrent Primary Cutaneous Anaplastic Large Cell Lymphoma
        Recurrent Subcutaneous Panniculitis-Like T-Cell Lymphoma

Professional guidelines

PubMed

Rituximab Treatment of Primary Cutaneous Follicle Center Lymphoma: A Retrospective Review.

Wang S, Perlmutter JW, Johnston J, Nugent Z, Wiseman M
J Cutan Med Surg 2022 Nov-Dec;26(6):604-612. Epub 2022 Sep 22 doi: 10.1177/12034754221126119. PMID: 36134749 Free PMC Article

Cutaneous primary B-cell lymphomas: from diagnosis to treatment.

Lima M
An Bras Dermatol 2015 Sep-Oct;90(5):687-706. doi: 10.1590/abd1806-4841.20153638. PMID: 26560215 Free PMC Article

Lymphoma-associated skin cancer: incidence, natural history, and clinical management.

Brewer JD, Habermann TM, Shanafelt TD
Int J Dermatol 2014 Mar;53(3):267-74. Epub 2013 Dec 10 doi: 10.1111/ijd.12208. PMID: 24320558

See all (32)

Recent clinical studies

Etiology

Management of malignant cutaneous wounds in oncologic patients.

Starace M, Carpanese MA, Pampaloni F, Dika E, Pileri A, Rubino D, Alessandrini A, Zamagni C, Baraldi C, Misciali C, Patrizi A, Bianchi T, Apalla Z, Piraccini BM
Support Care Cancer 2022 Sep;30(9):7615-7623. Epub 2022 Jun 8 doi: 10.1007/s00520-022-07194-0. PMID: 35672478 Free PMC Article

Genetic and epigenetic insights into cutaneous T-cell lymphoma.

Tensen CP, Quint KD, Vermeer MH
Blood 2022 Jan 6;139(1):15-33. doi: 10.1182/blood.2019004256. PMID: 34570882

AUGMENT: A Phase III Study of Lenalidomide Plus Rituximab Versus Placebo Plus Rituximab in Relapsed or Refractory Indolent Lymphoma.

Leonard JP, Trneny M, Izutsu K, Fowler NH, Hong X, Zhu J, Zhang H, Offner F, Scheliga A, Nowakowski GS, Pinto A, Re F, Fogliatto LM, Scheinberg P, Flinn IW, Moreira C, Cabeçadas J, Liu D, Kalambakas S, Fustier P, Wu C, Gribben JG; AUGMENT Trial Investigators
J Clin Oncol 2019 May 10;37(14):1188-1199. Epub 2019 Mar 21 doi: 10.1200/JCO.19.00010. PMID: 30897038 Free PMC Article

Mogamulizumab versus vorinostat in previously treated cutaneous T-cell lymphoma (MAVORIC): an international, open-label, randomised, controlled phase 3 trial.

Kim YH, Bagot M, Pinter-Brown L, Rook AH, Porcu P, Horwitz SM, Whittaker S, Tokura Y, Vermeer M, Zinzani PL, Sokol L, Morris S, Kim EJ, Ortiz-Romero PL, Eradat H, Scarisbrick J, Tsianakas A, Elmets C, Dalle S, Fisher DC, Halwani A, Poligone B, Greer J, Fierro MT, Khot A, Moskowitz AJ, Musiek A, Shustov A, Pro B, Geskin LJ, Dwyer K, Moriya J, Leoni M, Humphrey JS, Hudgens S, Grebennik DO, Tobinai K, Duvic M; MAVORIC Investigators
Lancet Oncol 2018 Sep;19(9):1192-1204. Epub 2018 Aug 9 doi: 10.1016/S1470-2045(18)30379-6. PMID: 30100375

Extranodal Diffuse Large B Cell Lymphoma: Molecular Features, Prognosis, and Risk of Central Nervous System Recurrence.

Ollila TA, Olszewski AJ
Curr Treat Options Oncol 2018 Jun 21;19(8):38. doi: 10.1007/s11864-018-0555-8. PMID: 29931605 Free PMC Article

See all (181)

Diagnosis

The many faces of Atypical fibroxanthoma.

Agaimy A
Semin Diagn Pathol 2023 Jul;40(4):306-312. Epub 2023 Jun 23 doi: 10.1053/j.semdp.2023.06.001. PMID: 37438163

Genetic and epigenetic insights into cutaneous T-cell lymphoma.

Tensen CP, Quint KD, Vermeer MH
Blood 2022 Jan 6;139(1):15-33. doi: 10.1182/blood.2019004256. PMID: 34570882

T-cell and NK-cell lymphomas in the lung.

Pan Z, Xu ML
Semin Diagn Pathol 2020 Nov;37(6):273-282. Epub 2020 May 16 doi: 10.1053/j.semdp.2020.04.003. PMID: 32448591

Extranodal Diffuse Large B Cell Lymphoma: Molecular Features, Prognosis, and Risk of Central Nervous System Recurrence.

Ollila TA, Olszewski AJ
Curr Treat Options Oncol 2018 Jun 21;19(8):38. doi: 10.1007/s11864-018-0555-8. PMID: 29931605 Free PMC Article

Lymphoma of the eyelid.

Svendsen FH, Heegaard S
Surv Ophthalmol 2017 May-Jun;62(3):312-331. Epub 2016 Nov 26 doi: 10.1016/j.survophthal.2016.11.009. PMID: 27894880

See all (212)

Therapy

Rituximab Treatment of Primary Cutaneous Follicle Center Lymphoma: A Retrospective Review.

Wang S, Perlmutter JW, Johnston J, Nugent Z, Wiseman M
J Cutan Med Surg 2022 Nov-Dec;26(6):604-612. Epub 2022 Sep 22 doi: 10.1177/12034754221126119. PMID: 36134749 Free PMC Article

AUGMENT: A Phase III Study of Lenalidomide Plus Rituximab Versus Placebo Plus Rituximab in Relapsed or Refractory Indolent Lymphoma.

Mogamulizumab versus vorinostat in previously treated cutaneous T-cell lymphoma (MAVORIC): an international, open-label, randomised, controlled phase 3 trial.

Outcomes of radiation therapy of indolent cutaneous B-cell lymphomas and literature review.

Gauci ML, Quero L, Ram-Wolff C, Guillerm S, M'Barek B, Lebbé C, Bagot M, Hennequin C
J Eur Acad Dermatol Venereol 2018 Oct;32(10):1668-1673. Epub 2018 May 18 doi: 10.1111/jdv.14972. PMID: 29578630

Brentuximab vedotin or physician's choice in CD30-positive cutaneous T-cell lymphoma (ALCANZA): an international, open-label, randomised, phase 3, multicentre trial.

Prince HM, Kim YH, Horwitz SM, Dummer R, Scarisbrick J, Quaglino P, Zinzani PL, Wolter P, Sanches JA, Ortiz-Romero PL, Akilov OE, Geskin L, Trotman J, Taylor K, Dalle S, Weichenthal M, Walewski J, Fisher D, Dréno B, Stadler R, Feldman T, Kuzel TM, Wang Y, Palanca-Wessels MC, Zagadailov E, Trepicchio WL, Zhang W, Lin HM, Liu Y, Huebner D, Little M, Whittaker S, Duvic M; ALCANZA study group
Lancet 2017 Aug 5;390(10094):555-566. Epub 2017 Jun 7 doi: 10.1016/S0140-6736(17)31266-7. PMID: 28600132

See all (173)

Prognosis

Clinicopathological, cytogenetic, and molecular profiles of primary cutaneous diffuse large B-cell lymphomas.

Uccella S, Goteri G, Maiorana A, Donati V, Tibiletti MG, Magnoli F, Facchi S, Merchiori D, Morsia E, Papotti R, Bettelli S, Forti E, Galimberti S, Rupoli S, Filosa A, Dardanis D, Bomben R, Braglia L, Pozzi S, Sacchi S
Hum Pathol 2023 Jun;136:44-55. Epub 2023 Mar 28 doi: 10.1016/j.humpath.2023.03.012. PMID: 36997030

Management of malignant cutaneous wounds in oncologic patients.

Genetic and epigenetic insights into cutaneous T-cell lymphoma.

Tensen CP, Quint KD, Vermeer MH
Blood 2022 Jan 6;139(1):15-33. doi: 10.1182/blood.2019004256. PMID: 34570882

Extranodal Diffuse Large B Cell Lymphoma: Molecular Features, Prognosis, and Risk of Central Nervous System Recurrence.

Ollila TA, Olszewski AJ
Curr Treat Options Oncol 2018 Jun 21;19(8):38. doi: 10.1007/s11864-018-0555-8. PMID: 29931605 Free PMC Article

Lymphoma of the eyelid.

Svendsen FH, Heegaard S
Surv Ophthalmol 2017 May-Jun;62(3):312-331. Epub 2016 Nov 26 doi: 10.1016/j.survophthal.2016.11.009. PMID: 27894880

See all (219)

Clinical prediction guides

Rituximab Treatment of Primary Cutaneous Follicle Center Lymphoma: A Retrospective Review.

Wang S, Perlmutter JW, Johnston J, Nugent Z, Wiseman M
J Cutan Med Surg 2022 Nov-Dec;26(6):604-612. Epub 2022 Sep 22 doi: 10.1177/12034754221126119. PMID: 36134749 Free PMC Article

Management of malignant cutaneous wounds in oncologic patients.

Primary cutaneous B-cell lymphoma: A single-center 5-year experience.

Jacob LA, Asati V, Lakshmaiah KC, Govind BK, Lokanatha D, Babu SM, Lokesh KN, Rudresh AH, Rajeev LK, Mulchandani NJ, Anand A, Koppaka D, Mysore SN
Indian J Cancer 2018 Apr-Jun;55(2):134-137. doi: 10.4103/ijc.IJC_418_17. PMID: 30604723

Mogamulizumab versus vorinostat in previously treated cutaneous T-cell lymphoma (MAVORIC): an international, open-label, randomised, controlled phase 3 trial.

Extranodal Diffuse Large B Cell Lymphoma: Molecular Features, Prognosis, and Risk of Central Nervous System Recurrence.

Ollila TA, Olszewski AJ
Curr Treat Options Oncol 2018 Jun 21;19(8):38. doi: 10.1007/s11864-018-0555-8. PMID: 29931605 Free PMC Article

See all (103)

Recent systematic reviews

Woringer-Kolopp disease (localized pagetoid reticulosis): a systematic review.

Osto M, Afify O, Musa A, Ahmed U, Rehman R, Mehregan D
Int J Dermatol 2023 Mar;62(3):312-321. Epub 2022 Apr 29 doi: 10.1111/ijd.16224. PMID: 35485962

Efficacy of Allogeneic Hematopoietic Cell Transplantation in Cutaneous T Cell Lymphoma: Results of a Systematic Review and Meta-Analysis.

Iqbal M, Reljic T, Ayala E, Sher T, Murthy H, Roy V, Foran J, Tun H, Kumar A, Kharfan-Dabaja MA
Biol Blood Marrow Transplant 2020 Jan;26(1):76-82. Epub 2019 Sep 5 doi: 10.1016/j.bbmt.2019.08.019. PMID: 31494227

EORTC, ISCL, and USCLC consensus recommendations for the treatment of primary cutaneous CD30-positive lymphoproliferative disorders: lymphomatoid papulosis and primary cutaneous anaplastic large-cell lymphoma.

Kempf W, Pfaltz K, Vermeer MH, Cozzio A, Ortiz-Romero PL, Bagot M, Olsen E, Kim YH, Dummer R, Pimpinelli N, Whittaker S, Hodak E, Cerroni L, Berti E, Horwitz S, Prince HM, Guitart J, Estrach T, Sanches JA, Duvic M, Ranki A, Dreno B, Ostheeren-Michaelis S, Knobler R, Wood G, Willemze R
Blood 2011 Oct 13;118(15):4024-35. Epub 2011 Aug 12 doi: 10.1182/blood-2011-05-351346. PMID: 21841159 Free PMC Article

See all (3)

MedGen

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Recurrent Primary Cutaneous Lymphoma

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Practice guidelines

Related information

Recent activity