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Extragonadal teratoma

MedGen UID:
1646497
Concept ID:
C4708601
Neoplastic Process
Synonyms: Extragonadal Teratoma; extragonadal teratoma
SNOMED CT: Extragonadal teratoma (768937006)
 
Monarch Initiative: MONDO:0019500
Orphanet: ORPHA883

Definition

An extremely rare, benign or malignant germ cell tumor characterized, clinically, by a teratoma presenting in an extragonadal location (for example retroperitoneum, mediastinum, craniofacial or sacrococcygeal region, intraosseous, solid organs) and histologically by displaying well-differentiated structures as well as immature elements. Presenting symptoms are variable depending on size and location of tumor. [from SNOMEDCT_US]

Professional guidelines

PubMed

Abdur-Rahman LO, Baba S, Bamigbola KT, Olaoye I, Oyinloye AO, Nasir AA, Adeniran JO
Afr J Paediatr Surg 2013 Oct-Dec;10(4):323-6. doi: 10.4103/0189-6725.125432. PMID: 24469482

Recent clinical studies

Etiology

Kanneganti A, Bhadiraju P, Tong PSY
Eur J Obstet Gynecol Reprod Biol 2021 Jul;262:134-141. Epub 2021 May 7 doi: 10.1016/j.ejogrb.2021.05.005. PMID: 34022590
Balci M, Yuksel U, Akkaya MA, Akkaya S, Sagsoz N
Childs Nerv Syst 2021 Jul;37(7):2245-2249. Epub 2021 Jan 6 doi: 10.1007/s00381-020-05017-3. PMID: 33404722
Lee T, Seo Y, Han J, Kwon GY
Pathology 2019 Jan;51(1):62-66. Epub 2018 Nov 20 doi: 10.1016/j.pathol.2018.10.002. PMID: 30470411
Mylonas KS, Kao CS, Levy D, Lordello L, Dal Cin P, Masiakos PT, Oliva E
Pediatr Dev Pathol 2019 May-Jun;22(3):214-220. Epub 2018 Sep 3 doi: 10.1177/1093526618798771. PMID: 30176765
Abdur-Rahman LO, Baba S, Bamigbola KT, Olaoye I, Oyinloye AO, Nasir AA, Adeniran JO
Afr J Paediatr Surg 2013 Oct-Dec;10(4):323-6. doi: 10.4103/0189-6725.125432. PMID: 24469482

Diagnosis

Djokic M, Hadzialjevic B, Rankovic B, Dezman R, Tomazic A
Curr Oncol 2022 Jul 6;29(7):4717-4724. doi: 10.3390/curroncol29070374. PMID: 35877234Free PMC Article
Li J, Li S, Xiao D, Song J, Mao J, Yin J
J Int Med Res 2021 Sep;49(9):3000605211047076. doi: 10.1177/03000605211047076. PMID: 34586943Free PMC Article
Balci M, Yuksel U, Akkaya MA, Akkaya S, Sagsoz N
Childs Nerv Syst 2021 Jul;37(7):2245-2249. Epub 2021 Jan 6 doi: 10.1007/s00381-020-05017-3. PMID: 33404722
Saygın İ, Çakır E, Ercin ME
Turk J Pediatr 2020;62(3):509-513. doi: 10.24953/turkjped.2020.03.024. PMID: 32558433
Kakuda M, Matsuzaki S, Kobayashi E, Yoshino K, Morii E, Kimura T
J Minim Invasive Gynecol 2015 Nov-Dec;22(7):1311-7. Epub 2015 Jul 20 doi: 10.1016/j.jmig.2015.07.008. PMID: 26205577

Therapy

Tinkler SD, Roberts JT, Robinson MC, Ramsden PD
Clin Oncol (R Coll Radiol) 1996;8(1):59-61. doi: 10.1016/s0936-6555(05)80042-1. PMID: 8688365

Prognosis

Lee T, Seo Y, Han J, Kwon GY
Pathology 2019 Jan;51(1):62-66. Epub 2018 Nov 20 doi: 10.1016/j.pathol.2018.10.002. PMID: 30470411
Mylonas KS, Kao CS, Levy D, Lordello L, Dal Cin P, Masiakos PT, Oliva E
Pediatr Dev Pathol 2019 May-Jun;22(3):214-220. Epub 2018 Sep 3 doi: 10.1177/1093526618798771. PMID: 30176765
Abdur-Rahman LO, Baba S, Bamigbola KT, Olaoye I, Oyinloye AO, Nasir AA, Adeniran JO
Afr J Paediatr Surg 2013 Oct-Dec;10(4):323-6. doi: 10.4103/0189-6725.125432. PMID: 24469482
Heerema-McKenney A, Harrison MR, Bratton B, Farrell J, Zaloudek C
Am J Surg Pathol 2005 Jan;29(1):29-38. doi: 10.1097/01.pas.0000146006.46468.ef. PMID: 15613854
Sanchez-Hermosillo E, Sikirica M, Carter D, Valigorsky JM
Am J Forensic Med Pathol 1998 Mar;19(1):69-71. doi: 10.1097/00000433-199803000-00013. PMID: 9539396

Clinical prediction guides

Balci M, Yuksel U, Akkaya MA, Akkaya S, Sagsoz N
Childs Nerv Syst 2021 Jul;37(7):2245-2249. Epub 2021 Jan 6 doi: 10.1007/s00381-020-05017-3. PMID: 33404722
Kakuda M, Matsuzaki S, Kobayashi E, Yoshino K, Morii E, Kimura T
J Minim Invasive Gynecol 2015 Nov-Dec;22(7):1311-7. Epub 2015 Jul 20 doi: 10.1016/j.jmig.2015.07.008. PMID: 26205577

Recent systematic reviews

Kanneganti A, Bhadiraju P, Tong PSY
Eur J Obstet Gynecol Reprod Biol 2021 Jul;262:134-141. Epub 2021 May 7 doi: 10.1016/j.ejogrb.2021.05.005. PMID: 34022590

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