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Extragonadal teratoma

MedGen UID:
1646497
Concept ID:
C4708601
Neoplastic Process
Synonyms: Extragonadal Teratoma; extragonadal teratoma
SNOMED CT: Extragonadal teratoma (768937006)
 
Monarch Initiative: MONDO:0019500
Orphanet: ORPHA883

Definition

An extremely rare, benign or malignant germ cell tumor characterized, clinically, by a teratoma presenting in an extragonadal location (for example retroperitoneum, mediastinum, craniofacial or sacrococcygeal region, intraosseous, solid organs) and histologically by displaying well-differentiated structures as well as immature elements. Presenting symptoms are variable depending on size and location of tumor. [from SNOMEDCT_US]

Professional guidelines

PubMed

Abdur-Rahman LO, Baba S, Bamigbola KT, Olaoye I, Oyinloye AO, Nasir AA, Adeniran JO
Afr J Paediatr Surg 2013 Oct-Dec;10(4):323-6. doi: 10.4103/0189-6725.125432. PMID: 24469482

Recent clinical studies

Etiology

Kanneganti A, Bhadiraju P, Tong PSY
Eur J Obstet Gynecol Reprod Biol 2021 Jul;262:134-141. Epub 2021 May 7 doi: 10.1016/j.ejogrb.2021.05.005. PMID: 34022590
Balci M, Yuksel U, Akkaya MA, Akkaya S, Sagsoz N
Childs Nerv Syst 2021 Jul;37(7):2245-2249. Epub 2021 Jan 6 doi: 10.1007/s00381-020-05017-3. PMID: 33404722
Lee T, Seo Y, Han J, Kwon GY
Pathology 2019 Jan;51(1):62-66. Epub 2018 Nov 20 doi: 10.1016/j.pathol.2018.10.002. PMID: 30470411
Mylonas KS, Kao CS, Levy D, Lordello L, Dal Cin P, Masiakos PT, Oliva E
Pediatr Dev Pathol 2019 May-Jun;22(3):214-220. Epub 2018 Sep 3 doi: 10.1177/1093526618798771. PMID: 30176765
Abdur-Rahman LO, Baba S, Bamigbola KT, Olaoye I, Oyinloye AO, Nasir AA, Adeniran JO
Afr J Paediatr Surg 2013 Oct-Dec;10(4):323-6. doi: 10.4103/0189-6725.125432. PMID: 24469482

Diagnosis

Balci M, Yuksel U, Akkaya MA, Akkaya S, Sagsoz N
Childs Nerv Syst 2021 Jul;37(7):2245-2249. Epub 2021 Jan 6 doi: 10.1007/s00381-020-05017-3. PMID: 33404722
Saygın İ, Çakır E, Ercin ME
Turk J Pediatr 2020;62(3):509-513. doi: 10.24953/turkjped.2020.03.024. PMID: 32558433
Koh JS, Park JH, Kang CH
J Korean Med Sci 2009 Oct;24(5):989-91. Epub 2009 Sep 24 doi: 10.3346/jkms.2009.24.5.989. PMID: 19795008Free PMC Article
McKenney JK, Longacre TA
Hum Pathol 2008 Apr;39(4):629-32. Epub 2008 Mar 4 doi: 10.1016/j.humpath.2007.08.021. PMID: 18289636
McMillan A, Horwich A
Clin Radiol 1987 May;38(3):327-8. doi: 10.1016/s0009-9260(87)80088-0. PMID: 3581678

Therapy

Tinkler SD, Roberts JT, Robinson MC, Ramsden PD
Clin Oncol (R Coll Radiol) 1996;8(1):59-61. doi: 10.1016/s0936-6555(05)80042-1. PMID: 8688365

Prognosis

Lee T, Seo Y, Han J, Kwon GY
Pathology 2019 Jan;51(1):62-66. Epub 2018 Nov 20 doi: 10.1016/j.pathol.2018.10.002. PMID: 30470411
Mylonas KS, Kao CS, Levy D, Lordello L, Dal Cin P, Masiakos PT, Oliva E
Pediatr Dev Pathol 2019 May-Jun;22(3):214-220. Epub 2018 Sep 3 doi: 10.1177/1093526618798771. PMID: 30176765
Heerema-McKenney A, Harrison MR, Bratton B, Farrell J, Zaloudek C
Am J Surg Pathol 2005 Jan;29(1):29-38. doi: 10.1097/01.pas.0000146006.46468.ef. PMID: 15613854
Yoon JH, Kim J, Park C
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002 Dec;94(6):741-5. doi: 10.1067/moe.2002.125197. PMID: 12464901
Tinkler SD, Roberts JT, Robinson MC, Ramsden PD
Clin Oncol (R Coll Radiol) 1996;8(1):59-61. doi: 10.1016/s0936-6555(05)80042-1. PMID: 8688365

Clinical prediction guides

Balci M, Yuksel U, Akkaya MA, Akkaya S, Sagsoz N
Childs Nerv Syst 2021 Jul;37(7):2245-2249. Epub 2021 Jan 6 doi: 10.1007/s00381-020-05017-3. PMID: 33404722
Kakuda M, Matsuzaki S, Kobayashi E, Yoshino K, Morii E, Kimura T
J Minim Invasive Gynecol 2015 Nov-Dec;22(7):1311-7. Epub 2015 Jul 20 doi: 10.1016/j.jmig.2015.07.008. PMID: 26205577

Recent systematic reviews

Kanneganti A, Bhadiraju P, Tong PSY
Eur J Obstet Gynecol Reprod Biol 2021 Jul;262:134-141. Epub 2021 May 7 doi: 10.1016/j.ejogrb.2021.05.005. PMID: 34022590

Supplemental Content

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    Clinical resources

    Practice guidelines

    • PubMed
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