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Regional Malignant Urethral Neoplasm

MedGen UID:
167732
•Concept ID:
C0854918
•
Neoplastic Process
Synonyms: Local Malignant Neoplasm of the Urethra; Local Malignant Neoplasm of Urethra; Local Malignant Tumor of the Urethra; Local Malignant Tumor of Urethra; Local Malignant Urethra Neoplasm; Local Malignant Urethra Tumor; Local Malignant Urethral Neoplasm; Local Malignant Urethral Tumor; Regional Malignant Neoplasm of the Urethra; Regional Malignant Neoplasm of Urethra; Regional Malignant Tumor of the Urethra; Regional Malignant Tumor of Urethra; Regional Malignant Urethra Neoplasm; Regional Malignant Urethra Tumor; Regional Malignant Urethral Tumor

Definition

A malignant neoplasm of the urethra that has not spread to other regions. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRegional Malignant Urethral Neoplasm

Professional guidelines

PubMed

The epidemiology and role of surgery in the treatment of urethral clear cell carcinoma.
Patel M, Im J, Ivy A, Maraboyina S, Kim T
Int Urol Nephrol 2020 Jan;52(1):51-57. Epub 2019 Sep 25 doi: 10.1007/s11255-019-02289-w. PMID: 31555949
Radiotherapy and Hormone Treatment in Prostate Cancer.
Böhmer D, Wirth M, Miller K, Budach V, Heidenreich A, Wiegel T
Dtsch Arztebl Int 2016 Apr 8;113(14):235-41. doi: 10.3238/arztebl.2016.0235. PMID: 27146591Free PMC Article
Management of advanced primary urethral carcinomas.
Dayyani F, Hoffman K, Eifel P, Guo C, Vikram R, Pagliaro LC, Pettaway C
BJU Int 2014 Jul;114(1):25-31. Epub 2014 May 22 doi: 10.1111/bju.12630. PMID: 24447439

Recent clinical studies

Etiology

Incidence rates and contemporary trends in primary urethral cancer.
Wenzel M, Nocera L, Collà Ruvolo C, Würnschimmel C, Tian Z, Shariat SF, Saad F, Briganti A, Tilki D, Mandel P, Becker A, Kluth LA, Chun FKH, Karakiewicz PI
Cancer Causes Control 2021 Jun;32(6):627-634. Epub 2021 Mar 22 doi: 10.1007/s10552-021-01416-2. PMID: 33751293Free PMC Article
Carcinoma of the urethra.
Zhang M, Adeniran AJ, Vikram R, Tamboli P, Pettaway C, Bondaruk J, Liu J, Baggerly K, Czerniak B
Hum Pathol 2018 Feb;72:35-44. Epub 2017 Aug 18 doi: 10.1016/j.humpath.2017.08.006. PMID: 28827100Free PMC Article
Radiotherapy and Hormone Treatment in Prostate Cancer.
Böhmer D, Wirth M, Miller K, Budach V, Heidenreich A, Wiegel T
Dtsch Arztebl Int 2016 Apr 8;113(14):235-41. doi: 10.3238/arztebl.2016.0235. PMID: 27146591Free PMC Article
A Critical Analysis of the Current Knowledge of Surgical Anatomy of the Prostate Related to Optimisation of Cancer Control and Preservation of Continence and Erection in Candidates for Radical Prostatectomy: An Update.
Walz J, Epstein JI, Ganzer R, Graefen M, Guazzoni G, Kaouk J, Menon M, Mottrie A, Myers RP, Patel V, Tewari A, Villers A, Artibani W
Eur Urol 2016 Aug;70(2):301-11. Epub 2016 Feb 2 doi: 10.1016/j.eururo.2016.01.026. PMID: 26850969
Bladder cancer in Africa.
Heyns CF, van der Merwe A
Can J Urol 2008 Feb;15(1):3899-908. PMID: 18304401

Diagnosis

Morphologic spectrum of the epithelial tumors of the male and female urethra.
Cimadamore A, Lopez-Beltran A, Cheng L, Montironi R
Virchows Arch 2023 Dec;483(6):751-764. Epub 2023 May 26 doi: 10.1007/s00428-023-03565-y. PMID: 37233807Free PMC Article
Carcinoma of the urethra.
Zhang M, Adeniran AJ, Vikram R, Tamboli P, Pettaway C, Bondaruk J, Liu J, Baggerly K, Czerniak B
Hum Pathol 2018 Feb;72:35-44. Epub 2017 Aug 18 doi: 10.1016/j.humpath.2017.08.006. PMID: 28827100Free PMC Article
Prostate Cancer Screening.
Mulhem E, Fulbright N, Duncan N
Am Fam Physician 2015 Oct 15;92(8):683-8. PMID: 26554408
Management of advanced primary urethral carcinomas.
Dayyani F, Hoffman K, Eifel P, Guo C, Vikram R, Pagliaro LC, Pettaway C
BJU Int 2014 Jul;114(1):25-31. Epub 2014 May 22 doi: 10.1111/bju.12630. PMID: 24447439
Obstructive uropathy.
Tseng TY, Stoller ML
Clin Geriatr Med 2009 Aug;25(3):437-43. doi: 10.1016/j.cger.2009.06.003. PMID: 19765491

Therapy

Use of Surgery for Post-Prostatectomy Incontinence.
Nelson M, Dornbier R, Kirshenbaum E, Eguia E, Sweigert P, Baker M, Farooq A, McVary KT, Gonzalez CM, Gupta G, Bresler L
J Urol 2020 Apr;203(4):786-791. Epub 2019 Oct 23 doi: 10.1097/JU.0000000000000618. PMID: 31642741
Radiotherapy and Hormone Treatment in Prostate Cancer.
Böhmer D, Wirth M, Miller K, Budach V, Heidenreich A, Wiegel T
Dtsch Arztebl Int 2016 Apr 8;113(14):235-41. doi: 10.3238/arztebl.2016.0235. PMID: 27146591Free PMC Article
A Critical Analysis of the Current Knowledge of Surgical Anatomy of the Prostate Related to Optimisation of Cancer Control and Preservation of Continence and Erection in Candidates for Radical Prostatectomy: An Update.
Walz J, Epstein JI, Ganzer R, Graefen M, Guazzoni G, Kaouk J, Menon M, Mottrie A, Myers RP, Patel V, Tewari A, Villers A, Artibani W
Eur Urol 2016 Aug;70(2):301-11. Epub 2016 Feb 2 doi: 10.1016/j.eururo.2016.01.026. PMID: 26850969
Prostate Cancer Screening.
Mulhem E, Fulbright N, Duncan N
Am Fam Physician 2015 Oct 15;92(8):683-8. PMID: 26554408
Thermal monitoring: invasive, minimal-invasive and non-invasive approaches.
Wust P, Cho CH, Hildebrandt B, Gellermann J
Int J Hyperthermia 2006 May;22(3):255-62. doi: 10.1080/02656730600661149. PMID: 16754347

Prognosis

Cohort profile: Bladder Cancer Data Base Sweden (BladderBaSe) 2.0.
Häggström C, Hagberg O, Gårdmark T, Aljabery F, Ströck V, Hosseini A, Sherif A, Malmstrom PU, Söderkvist K, Ullén A, Jerlström T, Jahnson S, Liedberg F, Holmberg L
BMJ Open 2022 Dec 20;12(12):e064898. doi: 10.1136/bmjopen-2022-064898. PMID: 36600418Free PMC Article
Incidence rates and contemporary trends in primary urethral cancer.
Wenzel M, Nocera L, Collà Ruvolo C, Würnschimmel C, Tian Z, Shariat SF, Saad F, Briganti A, Tilki D, Mandel P, Becker A, Kluth LA, Chun FKH, Karakiewicz PI
Cancer Causes Control 2021 Jun;32(6):627-634. Epub 2021 Mar 22 doi: 10.1007/s10552-021-01416-2. PMID: 33751293Free PMC Article
Radiotherapy and Hormone Treatment in Prostate Cancer.
Böhmer D, Wirth M, Miller K, Budach V, Heidenreich A, Wiegel T
Dtsch Arztebl Int 2016 Apr 8;113(14):235-41. doi: 10.3238/arztebl.2016.0235. PMID: 27146591Free PMC Article
Management of advanced primary urethral carcinomas.
Dayyani F, Hoffman K, Eifel P, Guo C, Vikram R, Pagliaro LC, Pettaway C
BJU Int 2014 Jul;114(1):25-31. Epub 2014 May 22 doi: 10.1111/bju.12630. PMID: 24447439
Obstructive uropathy.
Tseng TY, Stoller ML
Clin Geriatr Med 2009 Aug;25(3):437-43. doi: 10.1016/j.cger.2009.06.003. PMID: 19765491

Clinical prediction guides

Nomogram predicting early urinary incontinence after radical prostatectomy.
Shen C, Zhu X, Chen Z, Zhang W, Chen X, Zheng B, Gu D
BMC Cancer 2024 Sep 3;24(1):1095. doi: 10.1186/s12885-024-12850-1. PMID: 39227825Free PMC Article
A Scientometric Visualization Analysis for Benign Prostatic Hyperplasia from 2016 to 2022.
Zhang F, Xu J, Sun C, Dai F, Zhu Q, Liang H
Urol Int 2023;107(2):111-125. Epub 2022 Dec 22 doi: 10.1159/000527792. PMID: 36549286Free PMC Article
Use of Surgery for Post-Prostatectomy Incontinence.
Nelson M, Dornbier R, Kirshenbaum E, Eguia E, Sweigert P, Baker M, Farooq A, McVary KT, Gonzalez CM, Gupta G, Bresler L
J Urol 2020 Apr;203(4):786-791. Epub 2019 Oct 23 doi: 10.1097/JU.0000000000000618. PMID: 31642741
Carcinoma of the urethra.
Zhang M, Adeniran AJ, Vikram R, Tamboli P, Pettaway C, Bondaruk J, Liu J, Baggerly K, Czerniak B
Hum Pathol 2018 Feb;72:35-44. Epub 2017 Aug 18 doi: 10.1016/j.humpath.2017.08.006. PMID: 28827100Free PMC Article
Prostate Cancer Screening.
Mulhem E, Fulbright N, Duncan N
Am Fam Physician 2015 Oct 15;92(8):683-8. PMID: 26554408

Recent systematic reviews

Efficacy and Incontinence Rates After Urethroplasty for Radiation-induced Urethral Stenosis: A Systematic Review and Meta-analysis.
Sapienza LG, Ning MS, Carvalho EF, Spratt D, Calsavara VF, McLaughlin PW, Gomes MJL, Baiocchi G, Abu-Isa E
Urology 2021 Jun;152:109-116. Epub 2021 Feb 22 doi: 10.1016/j.urology.2021.02.014. PMID: 33631205
Surgery for stress urinary incontinence due to presumed sphincter deficiency after prostate surgery.
Silva LA, Andriolo RB, Atallah ÁN, da Silva EM
Cochrane Database Syst Rev 2014 Sep 27;2014(9):CD008306. doi: 10.1002/14651858.CD008306.pub3. PMID: 25261861Free PMC Article
Risk assessment of upper tract urothelial carcinoma related to aristolochic acid.
Wu F, Wang T
Cancer Epidemiol Biomarkers Prev 2013 May;22(5):812-20. Epub 2013 Mar 5 doi: 10.1158/1055-9965.EPI-12-1386. PMID: 23462915Free PMC Article
High-intensity focused ultrasound in prostate cancer; a systematic literature review of the French Association of Urology.
Rebillard X, Soulié M, Chartier-Kastler E, Davin JL, Mignard JP, Moreau JL, Coulange C; Association Francaise d'Urologie
BJU Int 2008 May;101(10):1205-13. Epub 2008 Mar 4 doi: 10.1111/j.1464-410X.2008.07504.x. PMID: 18325057

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