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Urethra cancer

MedGen UID:
57565
•Concept ID:
C0153620
•
Neoplastic Process
Synonyms: cancer of urethra; Malignant Neoplasm of the Urethra; malignant neoplasm of the urethra; Malignant Neoplasm of Urethra; malignant neoplasm of urethra; Malignant Tumor of the Urethra; malignant tumor of the urethra; Malignant tumor of urethra; Malignant Tumor of Urethra; malignant tumor of urethra; malignant tumour of the urethra; malignant tumour of urethra; Malignant Urethra Neoplasm; malignant urethra neoplasm; Malignant Urethra Tumor; malignant urethra tumor; malignant urethra tumour; Malignant Urethral Neoplasm; malignant urethral neoplasm; Malignant urethral tumor; Malignant Urethral Tumor; malignant urethral tumor; malignant urethral tumour; urethra cancer; urethral Ca; urethral cancer
SNOMED CT: Malignant urethral tumor (363459007); Malignant tumor of urethra (363459007)
 
Monarch Initiative: MONDO:0004192

Definition

A primary or metastatic malignant neoplasm involving the urethra. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUrethra cancer

Professional guidelines

PubMed

Treatment and Outcomes of Primary Urethra Cancer.
Eng TY, Chen TW, Patel AJ, Vincent JN, Ha CS
Am J Clin Oncol 2018 Sep;41(9):905-908. doi: 10.1097/COC.0000000000000391. PMID: 28537991
MRI findings of radiation-induced changes in the urethra and periurethral tissues after treatment for prostate cancer.
Marigliano C, Donati OF, Vargas HA, Akin O, Goldman DA, Eastham JA, Zelefsky MJ, Hricak H
Eur J Radiol 2013 Dec;82(12):e775-81. Epub 2013 Sep 22 doi: 10.1016/j.ejrad.2013.09.011. PMID: 24119430Free PMC Article

Recent clinical studies

Etiology

Primary Squamous Cell Carcinoma of the Male Proximal Urethra: Outcomes from a Single Centre.
Castiglione F, Alnajjar HM, Christodoulidou M, Albersen M, Parnham A, Freeman A, Jameson C, Mitra A, Nigam R, Malone P, Muneer A; Trauma and Reconstructive Urology Working Party of the European Association of Urology Young Academic Urologists
Eur Urol Focus 2021 Jan;7(1):163-169. Epub 2019 Mar 7 doi: 10.1016/j.euf.2019.02.016. PMID: 30853605
Cancer Risk After Midurethral Sling Surgery Using Polypropylene Mesh.
Altman D, Rogers RG, Yin L, Tamussino K, Ye W, Iglesia CB
Obstet Gynecol 2018 Mar;131(3):469-474. doi: 10.1097/AOG.0000000000002496. PMID: 29420401
Treatment and Outcomes of Primary Urethra Cancer.
Eng TY, Chen TW, Patel AJ, Vincent JN, Ha CS
Am J Clin Oncol 2018 Sep;41(9):905-908. doi: 10.1097/COC.0000000000000391. PMID: 28537991
Second malignancies after prostate brachytherapy: incidence of bladder and colorectal cancers in patients with 15 years of potential follow-up.
Liauw SL, Sylvester JE, Morris CG, Blasko JC, Grimm PD
Int J Radiat Oncol Biol Phys 2006 Nov 1;66(3):669-73. Epub 2006 Aug 2 doi: 10.1016/j.ijrobp.2006.05.016. PMID: 16887293
Proximity of prostate cancer to the urethra: implications for minimally invasive ablative therapies.
Leibovich BC, Blute ML, Bostwick DG, Wilson TM, Pisansky TM, Davis BJ, Ramnani DM, Cheng L, Sebo TJ, Zincke H
Urology 2000 Nov 1;56(5):726-9. doi: 10.1016/s0090-4295(00)00792-5. PMID: 11068288

Diagnosis

Primary Squamous Cell Carcinoma of the Male Proximal Urethra: Outcomes from a Single Centre.
Castiglione F, Alnajjar HM, Christodoulidou M, Albersen M, Parnham A, Freeman A, Jameson C, Mitra A, Nigam R, Malone P, Muneer A; Trauma and Reconstructive Urology Working Party of the European Association of Urology Young Academic Urologists
Eur Urol Focus 2021 Jan;7(1):163-169. Epub 2019 Mar 7 doi: 10.1016/j.euf.2019.02.016. PMID: 30853605
Cancer Risk After Midurethral Sling Surgery Using Polypropylene Mesh.
Altman D, Rogers RG, Yin L, Tamussino K, Ye W, Iglesia CB
Obstet Gynecol 2018 Mar;131(3):469-474. doi: 10.1097/AOG.0000000000002496. PMID: 29420401
Treatment and Outcomes of Primary Urethra Cancer.
Eng TY, Chen TW, Patel AJ, Vincent JN, Ha CS
Am J Clin Oncol 2018 Sep;41(9):905-908. doi: 10.1097/COC.0000000000000391. PMID: 28537991
Prostate cancer detected by uPM3: radical prostatectomy findings.
Bostwick DG, Gould VE, Qian J, Susani M, Marberger M
Mod Pathol 2006 May;19(5):630-3. doi: 10.1038/modpathol.3800583. PMID: 16528369

Therapy

Primary Squamous Cell Carcinoma of the Male Proximal Urethra: Outcomes from a Single Centre.
Castiglione F, Alnajjar HM, Christodoulidou M, Albersen M, Parnham A, Freeman A, Jameson C, Mitra A, Nigam R, Malone P, Muneer A; Trauma and Reconstructive Urology Working Party of the European Association of Urology Young Academic Urologists
Eur Urol Focus 2021 Jan;7(1):163-169. Epub 2019 Mar 7 doi: 10.1016/j.euf.2019.02.016. PMID: 30853605
Cancer Risk After Midurethral Sling Surgery Using Polypropylene Mesh.
Altman D, Rogers RG, Yin L, Tamussino K, Ye W, Iglesia CB
Obstet Gynecol 2018 Mar;131(3):469-474. doi: 10.1097/AOG.0000000000002496. PMID: 29420401
Treatment and Outcomes of Primary Urethra Cancer.
Eng TY, Chen TW, Patel AJ, Vincent JN, Ha CS
Am J Clin Oncol 2018 Sep;41(9):905-908. doi: 10.1097/COC.0000000000000391. PMID: 28537991
Second malignancies after prostate brachytherapy: incidence of bladder and colorectal cancers in patients with 15 years of potential follow-up.
Liauw SL, Sylvester JE, Morris CG, Blasko JC, Grimm PD
Int J Radiat Oncol Biol Phys 2006 Nov 1;66(3):669-73. Epub 2006 Aug 2 doi: 10.1016/j.ijrobp.2006.05.016. PMID: 16887293

Prognosis

Cancer Risk After Midurethral Sling Surgery Using Polypropylene Mesh.
Altman D, Rogers RG, Yin L, Tamussino K, Ye W, Iglesia CB
Obstet Gynecol 2018 Mar;131(3):469-474. doi: 10.1097/AOG.0000000000002496. PMID: 29420401
Treatment and Outcomes of Primary Urethra Cancer.
Eng TY, Chen TW, Patel AJ, Vincent JN, Ha CS
Am J Clin Oncol 2018 Sep;41(9):905-908. doi: 10.1097/COC.0000000000000391. PMID: 28537991
Second malignancies after prostate brachytherapy: incidence of bladder and colorectal cancers in patients with 15 years of potential follow-up.
Liauw SL, Sylvester JE, Morris CG, Blasko JC, Grimm PD
Int J Radiat Oncol Biol Phys 2006 Nov 1;66(3):669-73. Epub 2006 Aug 2 doi: 10.1016/j.ijrobp.2006.05.016. PMID: 16887293
Proximity of prostate cancer to the urethra: implications for minimally invasive ablative therapies.
Leibovich BC, Blute ML, Bostwick DG, Wilson TM, Pisansky TM, Davis BJ, Ramnani DM, Cheng L, Sebo TJ, Zincke H
Urology 2000 Nov 1;56(5):726-9. doi: 10.1016/s0090-4295(00)00792-5. PMID: 11068288
Kidney cancer mortality in The Netherlands, 1950-94: prediction of a decreasing trend.
Kiemeney L, Van Berkel H, Witjes JA, Sonke GS, Debruyne FM, Straatman H
J Epidemiol Biostat 1999;4(4):303-11. PMID: 10764244

Clinical prediction guides

Cancer Risk After Midurethral Sling Surgery Using Polypropylene Mesh.
Altman D, Rogers RG, Yin L, Tamussino K, Ye W, Iglesia CB
Obstet Gynecol 2018 Mar;131(3):469-474. doi: 10.1097/AOG.0000000000002496. PMID: 29420401
Second malignancies after prostate brachytherapy: incidence of bladder and colorectal cancers in patients with 15 years of potential follow-up.
Liauw SL, Sylvester JE, Morris CG, Blasko JC, Grimm PD
Int J Radiat Oncol Biol Phys 2006 Nov 1;66(3):669-73. Epub 2006 Aug 2 doi: 10.1016/j.ijrobp.2006.05.016. PMID: 16887293
Prostate cancer detected by uPM3: radical prostatectomy findings.
Bostwick DG, Gould VE, Qian J, Susani M, Marberger M
Mod Pathol 2006 May;19(5):630-3. doi: 10.1038/modpathol.3800583. PMID: 16528369
Proximity of prostate cancer to the urethra: implications for minimally invasive ablative therapies.
Leibovich BC, Blute ML, Bostwick DG, Wilson TM, Pisansky TM, Davis BJ, Ramnani DM, Cheng L, Sebo TJ, Zincke H
Urology 2000 Nov 1;56(5):726-9. doi: 10.1016/s0090-4295(00)00792-5. PMID: 11068288
Kidney cancer mortality in The Netherlands, 1950-94: prediction of a decreasing trend.
Kiemeney L, Van Berkel H, Witjes JA, Sonke GS, Debruyne FM, Straatman H
J Epidemiol Biostat 1999;4(4):303-11. PMID: 10764244

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