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Regional ureteric cancer

MedGen UID:
167733
•Concept ID:
C0854921
•
Neoplastic Process
Synonyms: Local Malignant Ureter Neoplasm; Local Malignant Ureter Tumor; Local Malignant Ureteral Neoplasm; Local Malignant Ureteral Tumor; Regional Malignant Ureter Neoplasm; Regional Malignant Ureter Tumor; Regional Malignant Ureteral Neoplasm; Regional Malignant Ureteral Tumor; regional malignant ureteral tumor; regional malignant ureteral tumour; Regional Ureter Carcinoma; regional ureter carcinoma; regional ureteric cancer; Regional Ureteric Carcinoma; regional ureteric carcinoma
 
Monarch Initiative: MONDO:0001978

Definition

A carcinoma of the ureter that has not spread to other regions. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRegional ureteric cancer

Professional guidelines

PubMed

ACR Appropriateness Criteria® Renal Failure.
Expert Panel on Urologic Imaging, Wong-You-Cheong JJ, Nikolaidis P, Khatri G, Dogra VS, Ganeshan D, Goldfarb S, Gore JL, Gupta RT, Heilbrun ME, Lyshchik A, Metter DF, Purysko AS, Savage SJ, Smith AD, Wang ZJ, Wolfman DJ, Lockhart ME
J Am Coll Radiol 2021 May;18(5S):S174-S188. doi: 10.1016/j.jacr.2021.02.019. PMID: 33958111
Consultation on UTUC, Stockholm 2018: aspects of treatment.
Jung H, Giusti G, Fajkovic H, Herrmann T, Jones R, Straub M, Baard J, Osther PJS, Brehmer M
World J Urol 2019 Nov;37(11):2279-2287. Epub 2019 May 23 doi: 10.1007/s00345-019-02811-w. PMID: 31123852Free PMC Article
Contemporary Evaluation and Management of Upper Tract Urothelial Cancer.
Mandalapu RS, Matin SF
Urology 2016 Aug;94:17-23. Epub 2016 Feb 2 doi: 10.1016/j.urology.2015.12.035. PMID: 26850816

Recent clinical studies

Etiology

Primary chemoablation of low-grade upper tract urothelial carcinoma using UGN-101, a mitomycin-containing reverse thermal gel (OLYMPUS): an open-label, single-arm, phase 3 trial.
Kleinmann N, Matin SF, Pierorazio PM, Gore JL, Shabsigh A, Hu B, Chamie K, Godoy G, Hubosky S, Rivera M, O'Donnell M, Quek M, Raman JD, Knoedler JJ, Scherr D, Stern J, Weight C, Weizer A, Woods M, Kaimakliotis H, Smith AB, Linehan J, Coleman J, Humphreys MR, Pak R, Lifshitz D, Verni M, Adibi M, Amin MB, Seltzer E, Klein I, Konorty M, Strauss-Ayali D, Hakim G, Schoenberg M, Lerner SP
Lancet Oncol 2020 Jun;21(6):776-785. Epub 2020 Apr 29 doi: 10.1016/S1470-2045(20)30147-9. PMID: 32631491
Updates in the Eighth Edition of the Tumor-Node-Metastasis Staging Classification for Urologic Cancers.
Paner GP, Stadler WM, Hansel DE, Montironi R, Lin DW, Amin MB
Eur Urol 2018 Apr;73(4):560-569. Epub 2018 Jan 9 doi: 10.1016/j.eururo.2017.12.018. PMID: 29325693
Biological Behavior and Long-Term Outcomes of Carcinoma In Situ in Upper Urinary Tract Managed by Radical Nephroureterectomy.
Inamoto T, Matsuyama H, Ibuki N, Komura K, Takahara K, Fujimoto K, Shiina H, Sakano S, Nagao K, Miyake M, Tatsumi Y, Yasumoto H, Azuma H; Nishinihon Uro-Oncology Collaborative Group
J Urol 2018 Apr;199(4):933-939. Epub 2017 Oct 14 doi: 10.1016/j.juro.2017.10.019. PMID: 29037861
Epidemiology, diagnosis, preoperative evaluation and prognostic assessment of upper-tract urothelial carcinoma (UTUC).
Soria F, Shariat SF, Lerner SP, Fritsche HM, Rink M, Kassouf W, Spiess PE, Lotan Y, Ye D, Fernández MI, Kikuchi E, Chade DC, Babjuk M, Grollman AP, Thalmann GN
World J Urol 2017 Mar;35(3):379-387. Epub 2016 Sep 7 doi: 10.1007/s00345-016-1928-x. PMID: 27604375
Urinary system.
Lynch CF, Cohen MB
Cancer 1995 Jan 1;75(1 Suppl):316-29. doi: 10.1002/1097-0142(19950101)75:1+<316::aid-cncr2820751314>3.0.co;2-t. PMID: 8001003

Diagnosis

Updates in the Eighth Edition of the Tumor-Node-Metastasis Staging Classification for Urologic Cancers.
Paner GP, Stadler WM, Hansel DE, Montironi R, Lin DW, Amin MB
Eur Urol 2018 Apr;73(4):560-569. Epub 2018 Jan 9 doi: 10.1016/j.eururo.2017.12.018. PMID: 29325693
Biological Behavior and Long-Term Outcomes of Carcinoma In Situ in Upper Urinary Tract Managed by Radical Nephroureterectomy.
Inamoto T, Matsuyama H, Ibuki N, Komura K, Takahara K, Fujimoto K, Shiina H, Sakano S, Nagao K, Miyake M, Tatsumi Y, Yasumoto H, Azuma H; Nishinihon Uro-Oncology Collaborative Group
J Urol 2018 Apr;199(4):933-939. Epub 2017 Oct 14 doi: 10.1016/j.juro.2017.10.019. PMID: 29037861
Epidemiology, diagnosis, preoperative evaluation and prognostic assessment of upper-tract urothelial carcinoma (UTUC).
Soria F, Shariat SF, Lerner SP, Fritsche HM, Rink M, Kassouf W, Spiess PE, Lotan Y, Ye D, Fernández MI, Kikuchi E, Chade DC, Babjuk M, Grollman AP, Thalmann GN
World J Urol 2017 Mar;35(3):379-387. Epub 2016 Sep 7 doi: 10.1007/s00345-016-1928-x. PMID: 27604375
Obstructive uropathy.
Tseng TY, Stoller ML
Clin Geriatr Med 2009 Aug;25(3):437-43. doi: 10.1016/j.cger.2009.06.003. PMID: 19765491
Urinary system.
Lynch CF, Cohen MB
Cancer 1995 Jan 1;75(1 Suppl):316-29. doi: 10.1002/1097-0142(19950101)75:1+<316::aid-cncr2820751314>3.0.co;2-t. PMID: 8001003

Therapy

Primary chemoablation of low-grade upper tract urothelial carcinoma using UGN-101, a mitomycin-containing reverse thermal gel (OLYMPUS): an open-label, single-arm, phase 3 trial.
Kleinmann N, Matin SF, Pierorazio PM, Gore JL, Shabsigh A, Hu B, Chamie K, Godoy G, Hubosky S, Rivera M, O'Donnell M, Quek M, Raman JD, Knoedler JJ, Scherr D, Stern J, Weight C, Weizer A, Woods M, Kaimakliotis H, Smith AB, Linehan J, Coleman J, Humphreys MR, Pak R, Lifshitz D, Verni M, Adibi M, Amin MB, Seltzer E, Klein I, Konorty M, Strauss-Ayali D, Hakim G, Schoenberg M, Lerner SP
Lancet Oncol 2020 Jun;21(6):776-785. Epub 2020 Apr 29 doi: 10.1016/S1470-2045(20)30147-9. PMID: 32631491
Consultation on UTUC, Stockholm 2018: aspects of treatment.
Jung H, Giusti G, Fajkovic H, Herrmann T, Jones R, Straub M, Baard J, Osther PJS, Brehmer M
World J Urol 2019 Nov;37(11):2279-2287. Epub 2019 May 23 doi: 10.1007/s00345-019-02811-w. PMID: 31123852Free PMC Article
Contemporary Evaluation and Management of Upper Tract Urothelial Cancer.
Mandalapu RS, Matin SF
Urology 2016 Aug;94:17-23. Epub 2016 Feb 2 doi: 10.1016/j.urology.2015.12.035. PMID: 26850816
Hormone-refractory and metastatic prostate cancer - palliative radiotherapy.
Moser L, Schubert T, Hinkelbein W
Front Radiat Ther Oncol 2008;41:117-125. doi: 10.1159/000139886. PMID: 18544993
Major avoidable risk factors of cancer.
Tominaga S
Cancer Lett 1999 Sep;143 Suppl 1:S19-23. doi: 10.1016/s0304-3835(99)90005-8. PMID: 10546592

Prognosis

Updates in the Eighth Edition of the Tumor-Node-Metastasis Staging Classification for Urologic Cancers.
Paner GP, Stadler WM, Hansel DE, Montironi R, Lin DW, Amin MB
Eur Urol 2018 Apr;73(4):560-569. Epub 2018 Jan 9 doi: 10.1016/j.eururo.2017.12.018. PMID: 29325693
Biological Behavior and Long-Term Outcomes of Carcinoma In Situ in Upper Urinary Tract Managed by Radical Nephroureterectomy.
Inamoto T, Matsuyama H, Ibuki N, Komura K, Takahara K, Fujimoto K, Shiina H, Sakano S, Nagao K, Miyake M, Tatsumi Y, Yasumoto H, Azuma H; Nishinihon Uro-Oncology Collaborative Group
J Urol 2018 Apr;199(4):933-939. Epub 2017 Oct 14 doi: 10.1016/j.juro.2017.10.019. PMID: 29037861
Fetal surgery: a critical review.
Kitagawa H, Pringle KC
Pediatr Surg Int 2017 Apr;33(4):421-433. Epub 2017 Jan 5 doi: 10.1007/s00383-016-4044-5. PMID: 28058487
Epidemiology, diagnosis, preoperative evaluation and prognostic assessment of upper-tract urothelial carcinoma (UTUC).
Soria F, Shariat SF, Lerner SP, Fritsche HM, Rink M, Kassouf W, Spiess PE, Lotan Y, Ye D, Fernández MI, Kikuchi E, Chade DC, Babjuk M, Grollman AP, Thalmann GN
World J Urol 2017 Mar;35(3):379-387. Epub 2016 Sep 7 doi: 10.1007/s00345-016-1928-x. PMID: 27604375
Urinary system.
Lynch CF, Cohen MB
Cancer 1995 Jan 1;75(1 Suppl):316-29. doi: 10.1002/1097-0142(19950101)75:1+<316::aid-cncr2820751314>3.0.co;2-t. PMID: 8001003

Clinical prediction guides

Macroscopic somatic clonal expansion in morphologically normal human urothelium.
Li R, Du Y, Chen Z, Xu D, Lin T, Jin S, Wang G, Liu Z, Lu M, Chen X, Xu T, Bai F
Science 2020 Oct 2;370(6512):82-89. doi: 10.1126/science.aba7300. PMID: 33004515
Primary chemoablation of low-grade upper tract urothelial carcinoma using UGN-101, a mitomycin-containing reverse thermal gel (OLYMPUS): an open-label, single-arm, phase 3 trial.
Kleinmann N, Matin SF, Pierorazio PM, Gore JL, Shabsigh A, Hu B, Chamie K, Godoy G, Hubosky S, Rivera M, O'Donnell M, Quek M, Raman JD, Knoedler JJ, Scherr D, Stern J, Weight C, Weizer A, Woods M, Kaimakliotis H, Smith AB, Linehan J, Coleman J, Humphreys MR, Pak R, Lifshitz D, Verni M, Adibi M, Amin MB, Seltzer E, Klein I, Konorty M, Strauss-Ayali D, Hakim G, Schoenberg M, Lerner SP
Lancet Oncol 2020 Jun;21(6):776-785. Epub 2020 Apr 29 doi: 10.1016/S1470-2045(20)30147-9. PMID: 32631491
Nephrogenic adenoma of the urinary tract: A 6-year single center experience.
Turcan D, Acikalin MF, Yilmaz E, Canaz F, Arik D
Pathol Res Pract 2017 Jul;213(7):831-835. Epub 2017 Mar 25 doi: 10.1016/j.prp.2017.03.001. PMID: 28554748
Epidemiology, diagnosis, preoperative evaluation and prognostic assessment of upper-tract urothelial carcinoma (UTUC).
Soria F, Shariat SF, Lerner SP, Fritsche HM, Rink M, Kassouf W, Spiess PE, Lotan Y, Ye D, Fernández MI, Kikuchi E, Chade DC, Babjuk M, Grollman AP, Thalmann GN
World J Urol 2017 Mar;35(3):379-387. Epub 2016 Sep 7 doi: 10.1007/s00345-016-1928-x. PMID: 27604375
Radiochemotherapy for bladder cancer.
Ott OJ, Rödel C, Weiss C, Wittlinger M, St Krause F, Dunst J, Fietkau R, Sauer R
Clin Oncol (R Coll Radiol) 2009 Sep;21(7):557-65. Epub 2009 Jun 28 doi: 10.1016/j.clon.2009.05.005. PMID: 19564101

Recent systematic reviews

Epidemiology, diagnosis, preoperative evaluation and prognostic assessment of upper-tract urothelial carcinoma (UTUC).
Soria F, Shariat SF, Lerner SP, Fritsche HM, Rink M, Kassouf W, Spiess PE, Lotan Y, Ye D, Fernández MI, Kikuchi E, Chade DC, Babjuk M, Grollman AP, Thalmann GN
World J Urol 2017 Mar;35(3):379-387. Epub 2016 Sep 7 doi: 10.1007/s00345-016-1928-x. PMID: 27604375
Granulocyte colony-stimulating factor-producing upper urinary tract carcinoma: systematic review of 46 cases reported in Japan.
Matsumoto K, Hayakawa N, Nakamura S
Clin Oncol (R Coll Radiol) 2014 Dec;26(12):781-8. Epub 2014 Aug 30 doi: 10.1016/j.clon.2014.08.006. PMID: 25179323
Results and outcomes after endoscopic treatment of upper urinary tract carcinoma: the Austrian experience.
Fajkovic H, Klatte T, Nagele U, Dunzinger M, Zigeuner R, Hübner W, Remzi M
World J Urol 2013 Feb;31(1):37-44. Epub 2012 Sep 27 doi: 10.1007/s00345-012-0948-4. PMID: 23014836
Laparoscopic versus open nephroureterectomy for the treatment of upper urinary tract urothelial carcinoma: a systematic review and cumulative analysis of comparative studies.
Ni S, Tao W, Chen Q, Liu L, Jiang H, Hu H, Han R, Wang C
Eur Urol 2012 Jun;61(6):1142-53. Epub 2012 Feb 15 doi: 10.1016/j.eururo.2012.02.019. PMID: 22349569
Surgical management for upper urinary tract transitional cell carcinoma.
Rai BP, Shelley M, Coles B, Biyani CS, El-Mokadem I, Nabi G
Cochrane Database Syst Rev 2011 Apr 13;(4):CD007349. doi: 10.1002/14651858.CD007349.pub2. PMID: 21491399

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