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Sinonasal Exophytic Papilloma

MedGen UID:
1708364
•Concept ID:
C5236091
•
Neoplastic Process
Synonym: Sinonasal Exophytic Schneiderian Papilloma

Definition

A papilloma with an exophytic growth arising from the sinonasal track. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSinonasal Exophytic Papilloma

Professional guidelines

PubMed

Letter to the editor regarding "Intralesional cidofovir injections for the treatment of multifocal exophytic sinonasal papilloma": The utility of topical cidofovir.
Halle BR, Kuan EC, Shive M
Int Forum Allergy Rhinol 2024 Oct;14(10):1667-1668. Epub 2024 Aug 23 doi: 10.1002/alr.23437. PMID: 39177067
Reply to: "Intralesional cidofovir injections for the treatment of multifocal exophytic sinonasal papilloma": The utility of topical cidofovir.
Chatelet F, Vinciguerra A, Marc M, Verillaud B, Herman P
Int Forum Allergy Rhinol 2024 Sep;14(9):1543. Epub 2024 Aug 20 doi: 10.1002/alr.23436. PMID: 39162104
Interferon alpha-2b treatment for exophytic nasal papillomas and human papillomavirus infection.
Inga P, Pavel T, Tatiana D, Svetlana S, Timur S, Irina A, Andrey B, Vladimir P, Anastasia K, Irada I
Braz J Otorhinolaryngol 2024 Sep-Oct;90(5):101449. Epub 2024 Jun 3 doi: 10.1016/j.bjorl.2024.101449. PMID: 38972285Free PMC Article

Recent clinical studies

Etiology

Sinonasal Papillomas: 10-Year Retrospective Analysis of Etiology, Epidemiology, and Recurrence.
Archang M, Chew L, Han AY, Sajed D, Vorasubin N, Wang M
Am J Rhinol Allergy 2022 Nov;36(6):827-834. Epub 2022 Aug 2 doi: 10.1177/19458924221116441. PMID: 35915990
Conjunctival Exophytic Schneiderian-type Papillomas: A Rare Occurrence.
Charles NC, Stagner AM, Raju LV, Belinsky I
Ophthalmic Plast Reconstr Surg 2021 Sep-Oct 01;37(5):e179-e181. doi: 10.1097/IOP.0000000000001983. PMID: 34284422
Sinonasal inverted papilloma: rate of recurrence and malignant transformation in 44 operated patients.
Sbrana MF, Borges RFR, Pinna FR, Neto DB, Voegels RL
Braz J Otorhinolaryngol 2021 Jan-Feb;87(1):80-84. Epub 2019 Aug 12 doi: 10.1016/j.bjorl.2019.07.003. PMID: 31455578Free PMC Article
Exophytic sinonasal papillomas and nasal florid papillomatosis: A retrospective study.
Glâtre R, De Kermadec H, Alsamad IA, Badoual C, Gauthier A, Brugel L, Parra C, Coste A, Prulière-Escabasse V, Bequignon E
Head Neck 2018 Apr;40(4):740-746. Epub 2018 Jan 17 doi: 10.1002/hed.25042. PMID: 29341451
Malignant transformation of sinonasal inverted papilloma and related genetic alterations: a systematic review.
Re M, Gioacchini FM, Bajraktari A, Tomasetti M, Kaleci S, Rubini C, Bertini A, Magliulo G, Pasquini E
Eur Arch Otorhinolaryngol 2017 Aug;274(8):2991-3000. Epub 2017 Apr 21 doi: 10.1007/s00405-017-4571-2. PMID: 28432463

Diagnosis

Sinonasal inverted papilloma: rate of recurrence and malignant transformation in 44 operated patients.
Sbrana MF, Borges RFR, Pinna FR, Neto DB, Voegels RL
Braz J Otorhinolaryngol 2021 Jan-Feb;87(1):80-84. Epub 2019 Aug 12 doi: 10.1016/j.bjorl.2019.07.003. PMID: 31455578Free PMC Article
The papillomas of the sinonasal tract. A comprehensive review.
Leoncini G, Zanetti L
Pathologica 2017 Mar;109(1):31-34. PMID: 28635991
Detection of human papillomavirus in sinonasal papillomas: systematic review and meta-analysis.
Syrjänen K, Syrjänen S
Laryngoscope 2013 Jan;123(1):181-92. Epub 2012 Nov 14 doi: 10.1002/lary.23688. PMID: 23161522
Hamartomas, papillomas and adenocarcinomas of the sinonasal tract and nasopharynx.
Perez-Ordoñez B
J Clin Pathol 2009 Dec;62(12):1085-95. doi: 10.1136/jcp.2007.053702. PMID: 19946095
Oncocytic Schneiderian papilloma.
Liu CY, Tsai TL, Hsu CY, Lin CZ
J Chin Med Assoc 2004 May;67(5):255-7. PMID: 15357115

Therapy

Interferon alpha-2b treatment for exophytic nasal papillomas and human papillomavirus infection.
Inga P, Pavel T, Tatiana D, Svetlana S, Timur S, Irina A, Andrey B, Vladimir P, Anastasia K, Irada I
Braz J Otorhinolaryngol 2024 Sep-Oct;90(5):101449. Epub 2024 Jun 3 doi: 10.1016/j.bjorl.2024.101449. PMID: 38972285Free PMC Article
Intralesional cidofovir injections for the treatment of multifocal exophytic sinonasal papilloma.
Chatelet F, Vinciguerra A, Marc M, Herman P, Verillaud B
Int Forum Allergy Rhinol 2024 Nov;14(11):1834-1837. Epub 2024 Jun 27 doi: 10.1002/alr.23399. PMID: 38934682
Detection of human papillomavirus in sinonasal papillomas: systematic review and meta-analysis.
Syrjänen K, Syrjänen S
Laryngoscope 2013 Jan;123(1):181-92. Epub 2012 Nov 14 doi: 10.1002/lary.23688. PMID: 23161522

Prognosis

Sinonasal Papillomas: 10-Year Retrospective Analysis of Etiology, Epidemiology, and Recurrence.
Archang M, Chew L, Han AY, Sajed D, Vorasubin N, Wang M
Am J Rhinol Allergy 2022 Nov;36(6):827-834. Epub 2022 Aug 2 doi: 10.1177/19458924221116441. PMID: 35915990
DEK-AFF2 Carcinoma of the Sinonasal Region and Skull Base: Detailed Clinicopathologic Characterization of a Distinctive Entity.
Rooper LM, Agaimy A, Dickson BC, Dueber JC, Eberhart CG, Gagan J, Hartmann A, Khararjian A, London NR, MacMillan CM, Palsgrove DN, Nix JS, Sandison A, Stoehr R, Truong T, Weinreb I, Bishop JA
Am J Surg Pathol 2021 Dec 1;45(12):1682-1693. doi: 10.1097/PAS.0000000000001741. PMID: 34049316
Exophytic sinonasal papillomas and nasal florid papillomatosis: A retrospective study.
Glâtre R, De Kermadec H, Alsamad IA, Badoual C, Gauthier A, Brugel L, Parra C, Coste A, Prulière-Escabasse V, Bequignon E
Head Neck 2018 Apr;40(4):740-746. Epub 2018 Jan 17 doi: 10.1002/hed.25042. PMID: 29341451
The papillomas of the sinonasal tract. A comprehensive review.
Leoncini G, Zanetti L
Pathologica 2017 Mar;109(1):31-34. PMID: 28635991
Hamartomas, papillomas and adenocarcinomas of the sinonasal tract and nasopharynx.
Perez-Ordoñez B
J Clin Pathol 2009 Dec;62(12):1085-95. doi: 10.1136/jcp.2007.053702. PMID: 19946095

Clinical prediction guides

Interferon alpha-2b treatment for exophytic nasal papillomas and human papillomavirus infection.
Inga P, Pavel T, Tatiana D, Svetlana S, Timur S, Irina A, Andrey B, Vladimir P, Anastasia K, Irada I
Braz J Otorhinolaryngol 2024 Sep-Oct;90(5):101449. Epub 2024 Jun 3 doi: 10.1016/j.bjorl.2024.101449. PMID: 38972285Free PMC Article
CD163 Immunohistochemical "Circle Sign" Staining Pattern Differentiates Sinonasal Papillomas From Morphologically Similar Non-neoplastic Lesions.
Sterling BC, Mehrad M, Ely KA, Lewis JS Jr
Am J Surg Pathol 2022 Nov 1;46(11):1507-1513. Epub 2022 Aug 23 doi: 10.1097/PAS.0000000000001953. PMID: 35993580Free PMC Article
Sinonasal Papillomas: 10-Year Retrospective Analysis of Etiology, Epidemiology, and Recurrence.
Archang M, Chew L, Han AY, Sajed D, Vorasubin N, Wang M
Am J Rhinol Allergy 2022 Nov;36(6):827-834. Epub 2022 Aug 2 doi: 10.1177/19458924221116441. PMID: 35915990
Human Papilloma Virus (HPV) in Sinonasal Papillomas and Squamous Cell Carcinomas: A PCR-based Study of 60 cases.
Beigh A, Rashi R, Junaid S, Khuroo MS, Farook S
Gulf J Oncolog 2018 Jan;1(26):37-42. PMID: 29607821
Inflammation and the pathogenesis of inverted papilloma.
Roh HJ, Procop GW, Batra PS, Citardi MJ, Lanza DC
Am J Rhinol 2004 Mar-Apr;18(2):65-74. PMID: 15152870

Recent systematic reviews

Malignant transformation of sinonasal inverted papilloma and related genetic alterations: a systematic review.
Re M, Gioacchini FM, Bajraktari A, Tomasetti M, Kaleci S, Rubini C, Bertini A, Magliulo G, Pasquini E
Eur Arch Otorhinolaryngol 2017 Aug;274(8):2991-3000. Epub 2017 Apr 21 doi: 10.1007/s00405-017-4571-2. PMID: 28432463
Detection of human papillomavirus in sinonasal papillomas: systematic review and meta-analysis.
Syrjänen K, Syrjänen S
Laryngoscope 2013 Jan;123(1):181-92. Epub 2012 Nov 14 doi: 10.1002/lary.23688. PMID: 23161522

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