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Locally Advanced Renal Pelvis Carcinoma

MedGen UID:
1750328
•Concept ID:
C5419561
•
Neoplastic Process

Definition

Renal pelvis carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLocally Advanced Renal Pelvis Carcinoma

Professional guidelines

PubMed

Optimal management of recurrent and metastatic upper tract urothelial carcinoma: Implications of intensity modulated radiation therapy.
Kim MS, Koom WS, Cho JH, Kim SY, Lee IJ
Radiat Oncol 2022 Mar 9;17(1):51. doi: 10.1186/s13014-022-02020-7. PMID: 35264197Free PMC Article
European Association of Urology Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2020 Update.
Rouprêt M, Babjuk M, Burger M, Capoun O, Cohen D, Compérat EM, Cowan NC, Dominguez-Escrig JL, Gontero P, Hugh Mostafid A, Palou J, Peyronnet B, Seisen T, Soukup V, Sylvester RJ, Rhijn BWGV, Zigeuner R, Shariat SF
Eur Urol 2021 Jan;79(1):62-79. Epub 2020 Jun 24 doi: 10.1016/j.eururo.2020.05.042. PMID: 32593530
The role of systemic chemotherapy in management of upper tract urothelial cancer.
Gayed BA, Thoreson GR, Margulis V
Curr Urol Rep 2013 Apr;14(2):94-101. doi: 10.1007/s11934-013-0307-z. PMID: 23344684

Recent clinical studies

Etiology

Adjuvant Radiotherapy for Upper Tract Urothelial Carcinoma: Systematic Review and Meta-Analysis.
Zalay O, Yan M, Sigurdson S, Malone S, Vera-Badillo FE, Mahmud A
Curr Oncol 2022 Dec 20;30(1):19-36. doi: 10.3390/curroncol30010002. PMID: 36661651Free PMC Article
Immune checkpoint inhibition in upper tract urothelial carcinoma.
Califano G, Ouzaid I, Verze P, Hermieu JF, Mirone V, Xylinas E
World J Urol 2021 May;39(5):1357-1367. Epub 2020 Oct 31 doi: 10.1007/s00345-020-03502-7. PMID: 33128595
European Association of Urology Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2020 Update.
Rouprêt M, Babjuk M, Burger M, Capoun O, Cohen D, Compérat EM, Cowan NC, Dominguez-Escrig JL, Gontero P, Hugh Mostafid A, Palou J, Peyronnet B, Seisen T, Soukup V, Sylvester RJ, Rhijn BWGV, Zigeuner R, Shariat SF
Eur Urol 2021 Jan;79(1):62-79. Epub 2020 Jun 24 doi: 10.1016/j.eururo.2020.05.042. PMID: 32593530
Kidney-sparing surgery for upper tract urothelial cancer.
Lucca I, Klatte T, Rouprêt M, Shariat SF
Curr Opin Urol 2015 Mar;25(2):100-4. doi: 10.1097/MOU.0000000000000148. PMID: 25581542
Renal cancer.
Corgna E, Betti M, Gatta G, Roila F, De Mulder PH
Crit Rev Oncol Hematol 2007 Dec;64(3):247-62. Epub 2007 Jul 26 doi: 10.1016/j.critrevonc.2007.04.007. PMID: 17662611

Diagnosis

Advanced renal pelvis carcinoma patient with an ERBB2 insertion mutation: a case report.
Shang P, Lou C, Yin L, Tao C, Dong Y, Yang G, Yuan Z
J Int Med Res 2023 Nov;51(11):3000605231204502. doi: 10.1177/03000605231204502. PMID: 37917812Free PMC Article
Design and rationale of a single-arm phase II study of neoadjuvant Durvalumab and Gemcitabine associated with Cisplatin or Carboplatin for upper urinary tract urothelial cancer: the iNDUCT trial (NCT04617756).
Calleris G, Rouprêt M, Seisen T, Bendjeddou L, Chevallier T, Masson-Lecomte A, Thibault C, Neuzillet Y, Audenet F, Xylinas E, Houédé N
World J Urol 2023 Dec;41(12):3413-3420. Epub 2023 Sep 12 doi: 10.1007/s00345-023-04596-5. PMID: 37698632
European Association of Urology Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2020 Update.
Rouprêt M, Babjuk M, Burger M, Capoun O, Cohen D, Compérat EM, Cowan NC, Dominguez-Escrig JL, Gontero P, Hugh Mostafid A, Palou J, Peyronnet B, Seisen T, Soukup V, Sylvester RJ, Rhijn BWGV, Zigeuner R, Shariat SF
Eur Urol 2021 Jan;79(1):62-79. Epub 2020 Jun 24 doi: 10.1016/j.eururo.2020.05.042. PMID: 32593530
Recent advances in upper tract urothelial carcinomas: From bench to clinics.
Shao IH, Chang YH, Pang ST
Int J Urol 2019 Feb;26(2):148-159. Epub 2018 Oct 29 doi: 10.1111/iju.13826. PMID: 30372791
Renal cancer.
Corgna E, Betti M, Gatta G, Roila F, De Mulder PH
Crit Rev Oncol Hematol 2007 Dec;64(3):247-62. Epub 2007 Jul 26 doi: 10.1016/j.critrevonc.2007.04.007. PMID: 17662611

Therapy

Advanced renal pelvis carcinoma patient with an ERBB2 insertion mutation: a case report.
Shang P, Lou C, Yin L, Tao C, Dong Y, Yang G, Yuan Z
J Int Med Res 2023 Nov;51(11):3000605231204502. doi: 10.1177/03000605231204502. PMID: 37917812Free PMC Article
Design and rationale of a single-arm phase II study of neoadjuvant Durvalumab and Gemcitabine associated with Cisplatin or Carboplatin for upper urinary tract urothelial cancer: the iNDUCT trial (NCT04617756).
Calleris G, Rouprêt M, Seisen T, Bendjeddou L, Chevallier T, Masson-Lecomte A, Thibault C, Neuzillet Y, Audenet F, Xylinas E, Houédé N
World J Urol 2023 Dec;41(12):3413-3420. Epub 2023 Sep 12 doi: 10.1007/s00345-023-04596-5. PMID: 37698632
Adjuvant Radiotherapy for Upper Tract Urothelial Carcinoma: Systematic Review and Meta-Analysis.
Zalay O, Yan M, Sigurdson S, Malone S, Vera-Badillo FE, Mahmud A
Curr Oncol 2022 Dec 20;30(1):19-36. doi: 10.3390/curroncol30010002. PMID: 36661651Free PMC Article
Immune checkpoint inhibition in upper tract urothelial carcinoma.
Califano G, Ouzaid I, Verze P, Hermieu JF, Mirone V, Xylinas E
World J Urol 2021 May;39(5):1357-1367. Epub 2020 Oct 31 doi: 10.1007/s00345-020-03502-7. PMID: 33128595
Recent advances in upper tract urothelial carcinomas: From bench to clinics.
Shao IH, Chang YH, Pang ST
Int J Urol 2019 Feb;26(2):148-159. Epub 2018 Oct 29 doi: 10.1111/iju.13826. PMID: 30372791

Prognosis

Advanced renal pelvis carcinoma patient with an ERBB2 insertion mutation: a case report.
Shang P, Lou C, Yin L, Tao C, Dong Y, Yang G, Yuan Z
J Int Med Res 2023 Nov;51(11):3000605231204502. doi: 10.1177/03000605231204502. PMID: 37917812Free PMC Article
European Association of Urology Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2020 Update.
Rouprêt M, Babjuk M, Burger M, Capoun O, Cohen D, Compérat EM, Cowan NC, Dominguez-Escrig JL, Gontero P, Hugh Mostafid A, Palou J, Peyronnet B, Seisen T, Soukup V, Sylvester RJ, Rhijn BWGV, Zigeuner R, Shariat SF
Eur Urol 2021 Jan;79(1):62-79. Epub 2020 Jun 24 doi: 10.1016/j.eururo.2020.05.042. PMID: 32593530
Recent advances in upper tract urothelial carcinomas: From bench to clinics.
Shao IH, Chang YH, Pang ST
Int J Urol 2019 Feb;26(2):148-159. Epub 2018 Oct 29 doi: 10.1111/iju.13826. PMID: 30372791
Renal cancer.
Corgna E, Betti M, Gatta G, Roila F, De Mulder PH
Crit Rev Oncol Hematol 2007 Dec;64(3):247-62. Epub 2007 Jul 26 doi: 10.1016/j.critrevonc.2007.04.007. PMID: 17662611
Transitional cell carcinoma of the ureter and renal pelvis.
Kirkali Z, Tuzel E
Crit Rev Oncol Hematol 2003 Aug;47(2):155-69. doi: 10.1016/s1040-8428(03)00079-9. PMID: 12900009

Clinical prediction guides

Clinicopathologic Analysis of Micropapillary Urothelial Carcinoma of the Upper Urinary Tract: Implications for HER2-Targeted Therapy.
Chou LP, Hsu CW, Yang SF, Lee CT, Ou YC, Lin KC, Hu CY, Jou YC, Tsai YS, Chow NH
Clin Genitourin Cancer 2023 Aug;21(4):508.e1-508.e10. Epub 2023 Apr 20 doi: 10.1016/j.clgc.2023.04.002. PMID: 37183125
Tailored immunotherapy approach with nivolumab with or without ipilimumab in patients with advanced transitional cell carcinoma after platinum-based chemotherapy (TITAN-TCC): a multicentre, single-arm, phase 2 trial.
Grimm MO, Grün CB, Niegisch G, Pichler M, Roghmann F, Schmitz-Dräger B, Baretton G, Schmitz M, Bolenz C, Foller S, Leucht K, Schumacher U, Schostak M, Meran J, Loidl W, Zengerling F
Lancet Oncol 2023 Apr;24(4):347-359. Epub 2023 Feb 28 doi: 10.1016/S1470-2045(23)00053-0. PMID: 36868252
High Serum CA19-9 Concentration Indicates High Chemosensitivity and Better Survival in Advanced Urothelial Carcinoma.
Yaegashi H, Izumi K, Kadomoto S, Naito R, Makino T, Iwamoto H, Nohara T, Shigehara K, Kadono Y, Mizokami A
Anticancer Res 2019 Jan;39(1):375-380. doi: 10.21873/anticanres.13122. PMID: 30591483
Prognostic Impact of ALDH1 Expression in Transitional Cell Carcinoma of the Renal Pelvis.
Liu J, Jin J, Yang Y, Han W, Yu W, Shen C, Zhang N, Du P, Zhao Q, Wang S, Tang X
Anticancer Res 2015 Sep;35(9):4829-36. PMID: 26254374
Urothelial carcinoma of the renal pelvis: a clinicopathologic study of 130 cases.
Olgac S, Mazumdar M, Dalbagni G, Reuter VE
Am J Surg Pathol 2004 Dec;28(12):1545-52. doi: 10.1097/00000478-200412000-00001. PMID: 15577672

Recent systematic reviews

Adjuvant Radiotherapy for Upper Tract Urothelial Carcinoma: Systematic Review and Meta-Analysis.
Zalay O, Yan M, Sigurdson S, Malone S, Vera-Badillo FE, Mahmud A
Curr Oncol 2022 Dec 20;30(1):19-36. doi: 10.3390/curroncol30010002. PMID: 36661651Free PMC Article
Radical nephroureterectomy versus endoscopic procedures for the treatment of localised upper tract urothelial carcinoma: a meta-analysis and a systematic review of current evidence from comparative studies.
Yakoubi R, Colin P, Seisen T, Léon P, Nison L, Bozzini G, Shariat SF, Rouprêt M
Eur J Surg Oncol 2014 Dec;40(12):1629-34. Epub 2014 Jul 25 doi: 10.1016/j.ejso.2014.06.007. PMID: 25108813

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