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Sinonasal Keratinizing Squamous Cell Carcinoma

MedGen UID:
1752101
Concept ID:
C5420022
Neoplastic Process
Synonym: Nasal Cavity and Paranasal Sinus Keratinizing Squamous Cell Carcinoma

Definition

A squamous cell carcinoma that arises from the mucosal epithelium of the nasal cavity or the paranasal sinuses and is characterized by prominent production of keratin. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSinonasal Keratinizing Squamous Cell Carcinoma

Professional guidelines

PubMed

Bishop JA, Alaggio R, Zhang L, Seethala RR, Antonescu CR
Am J Surg Pathol 2015 Sep;39(9):1267-74. doi: 10.1097/PAS.0000000000000460. PMID: 26034869Free PMC Article
Singh L, Ranjan R, Arava S, Singh MK
Ann Diagn Pathol 2014 Oct;18(5):261-5. Epub 2014 Jan 13 doi: 10.1016/j.anndiagpath.2014.01.003. PMID: 25017972
Tilson MP, Bishop JA
Head Neck Pathol 2014 Jun;8(2):141-5. Epub 2013 Oct 11 doi: 10.1007/s12105-013-0496-2. PMID: 24114197Free PMC Article

Recent clinical studies

Etiology

Svajdler M, Nemcova J, Dubinsky P, Metelkova A, Svajdler P, Straka Ľ, Sakar R, Daum O, Michal M, Skalova A, Mezencev R
Neoplasma 2020 Nov;67(6):1456-1463. Epub 2020 Aug 27 doi: 10.4149/neo_2020_200330N332. PMID: 32853018
Al-Qurayshi Z, Smith R, Walsh JE
Ann Otol Rhinol Laryngol 2020 Nov;129(11):1049-1055. Epub 2020 May 31 doi: 10.1177/0003489420929048. PMID: 32476435
Rupp NJ, Camenisch U, Seidl K, Rushing EJ, Anderegg N, Broglie MA, Holzmann D, Morand GB
Head Neck Pathol 2020 Sep;14(3):623-629. Epub 2019 Sep 30 doi: 10.1007/s12105-019-01079-1. PMID: 31571045Free PMC Article
Chernock RD
Head Neck Pathol 2012 Jul;6 Suppl 1(Suppl 1):S41-7. Epub 2012 Jul 3 doi: 10.1007/s12105-012-0373-4. PMID: 22782222Free PMC Article
Wenig BM
Arch Pathol Lab Med 2009 May;133(5):699-712. doi: 10.5858/133.5.699. PMID: 19415944

Diagnosis

Bubola J, MacMillan CM, Weinreb I, Witterick I, Swanson D, Zhang L, Antonescu CR, Dickson BC
Head Neck Pathol 2021 Dec;15(4):1284-1288. Epub 2021 Jan 4 doi: 10.1007/s12105-020-01249-6. PMID: 33394379Free PMC Article
Al-Qurayshi Z, Smith R, Walsh JE
Ann Otol Rhinol Laryngol 2020 Nov;129(11):1049-1055. Epub 2020 May 31 doi: 10.1177/0003489420929048. PMID: 32476435
Rooper LM, Bishop JA
Surg Pathol Clin 2017 Mar;10(1):103-123. Epub 2016 Dec 28 doi: 10.1016/j.path.2016.10.005. PMID: 28153129
Simons SA, Bridge JA, Leon ME
Semin Diagn Pathol 2016 Mar;33(2):91-103. Epub 2015 Sep 10 doi: 10.1053/j.semdp.2015.09.010. PMID: 26585346
Wenig BM
Arch Pathol Lab Med 2009 May;133(5):699-712. doi: 10.5858/133.5.699. PMID: 19415944

Therapy

Palomba A, Iaia TE, Biancalani M, Conti S, Battista G, Papaleo B, Franchi A
Am J Rhinol 2008 Jul-Aug;22(4):356-60. doi: 10.2500/ajr.2008.22.3201. PMID: 18702897

Prognosis

Rooper LM, Agaimy A, Dickson BC, Dueber JC, Eberhart CG, Gagan J, Hartmann A, Khararjian A, London NR, MacMillan CM, Palsgrove DN, Nix JS, Sandison A, Stoehr R, Truong T, Weinreb I, Bishop JA
Am J Surg Pathol 2021 Dec 1;45(12):1682-1693. doi: 10.1097/PAS.0000000000001741. PMID: 34049316
Svajdler M, Nemcova J, Dubinsky P, Metelkova A, Svajdler P, Straka Ľ, Sakar R, Daum O, Michal M, Skalova A, Mezencev R
Neoplasma 2020 Nov;67(6):1456-1463. Epub 2020 Aug 27 doi: 10.4149/neo_2020_200330N332. PMID: 32853018
Al-Qurayshi Z, Smith R, Walsh JE
Ann Otol Rhinol Laryngol 2020 Nov;129(11):1049-1055. Epub 2020 May 31 doi: 10.1177/0003489420929048. PMID: 32476435
Kılıç S, Kılıç SS, Kim ES, Baredes S, Mahmoud O, Gray ST, Eloy JA
Int Forum Allergy Rhinol 2017 Oct;7(10):980-989. Epub 2017 Aug 31 doi: 10.1002/alr.21996. PMID: 28859244
Simons SA, Bridge JA, Leon ME
Semin Diagn Pathol 2016 Mar;33(2):91-103. Epub 2015 Sep 10 doi: 10.1053/j.semdp.2015.09.010. PMID: 26585346

Clinical prediction guides

Suzuki H, Sasaki E, Tamaki T, Kodaira T, Nishio M, Nishikawa D, Beppu S, Terada H, Sawabe M, Hanai N
Anticancer Res 2023 Jul;43(7):3247-3253. doi: 10.21873/anticanres.16499. PMID: 37351957
Rupp NJ, Camenisch U, Seidl K, Rushing EJ, Anderegg N, Broglie MA, Holzmann D, Morand GB
Head Neck Pathol 2020 Sep;14(3):623-629. Epub 2019 Sep 30 doi: 10.1007/s12105-019-01079-1. PMID: 31571045Free PMC Article
McHugh KE, Policarpio-Nicolas MLC
Acta Cytol 2019;63(5):431-437. Epub 2019 May 27 doi: 10.1159/000500351. PMID: 31132763
Kılıç S, Kılıç SS, Kim ES, Baredes S, Mahmoud O, Gray ST, Eloy JA
Int Forum Allergy Rhinol 2017 Oct;7(10):980-989. Epub 2017 Aug 31 doi: 10.1002/alr.21996. PMID: 28859244
Simons SA, Bridge JA, Leon ME
Semin Diagn Pathol 2016 Mar;33(2):91-103. Epub 2015 Sep 10 doi: 10.1053/j.semdp.2015.09.010. PMID: 26585346

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