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Advanced Hodgkin Lymphoma

MedGen UID:
1773787
•Concept ID:
C5419619
•
Neoplastic Process

Definition

Hodgkin lymphoma that has spread extensively to other anatomic sites or is no longer responding to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdvanced Hodgkin Lymphoma

Professional guidelines

PubMed

Contemporary treatment options for a classical disease: Advanced Hodgkin lymphoma.
Reid JH, Marini BL, Nachar VR, Brown AM, Devata S, Perissinotti AJ
Crit Rev Oncol Hematol 2020 Apr;148:102897. Epub 2020 Feb 13 doi: 10.1016/j.critrevonc.2020.102897. PMID: 32109715
Current treatment paradigms for advanced stage Hodgkin lymphoma.
Longley J, Johnson PWM
Br J Haematol 2019 Jan;184(1):60-71. Epub 2018 Nov 8 doi: 10.1111/bjh.15622. PMID: 30408156
Risk-Adapted Treatment of Advanced Hodgkin Lymphoma With PET-CT.
Lynch RC, Advani RH
Am Soc Clin Oncol Educ Book 2016;35:e376-85. doi: 10.1200/EDBK_159036. PMID: 27249744

Recent clinical studies

Etiology

Decision-Making among Experts in Advanced Hodgkin Lymphoma.
Hitz F, Lang N, Mey U, Mingrone W, Moccia A, Taverna C, Novak U, Stenner F, Schmidt A, Mamot C, Fischer N, Putora PM
Oncology 2023;101(3):159-165. Epub 2022 Sep 27 doi: 10.1159/000526360. PMID: 36103806
Neutropenia during frontline treatment of advanced Hodgkin lymphoma: Incidence, risk factors, and management.
Sureda A, Domingo-Domenech E, Gautam A
Crit Rev Oncol Hematol 2019 Jun;138:1-5. Epub 2019 Mar 29 doi: 10.1016/j.critrevonc.2019.03.016. PMID: 31092364
Current treatment paradigms for advanced stage Hodgkin lymphoma.
Longley J, Johnson PWM
Br J Haematol 2019 Jan;184(1):60-71. Epub 2018 Nov 8 doi: 10.1111/bjh.15622. PMID: 30408156
Does Radiation Have a Role in Advanced Stage Hodgkin's or Non-Hodgkin Lymphoma?
Specht L
Curr Treat Options Oncol 2016 Jan;17(1):4. doi: 10.1007/s11864-015-0377-x. PMID: 26739151
Refractory Hodgkin lymphoma.
von Tresckow B, Engert A
Curr Opin Oncol 2013 Sep;25(5):463-9. doi: 10.1097/01.cco.0000432524.62475.60. PMID: 23942291

Diagnosis

Advanced Hodgkin lymphoma with extensive cutaneous infiltration.
Esteves M, Nogueira A, Azevedo F
Indian J Dermatol Venereol Leprol 2022 Sep-Oct;88(5):680-681. doi: 10.25259/IJDVL_1071_19. PMID: 33666052
Relapsed, Refractory, or Advanced Hodgkin Lymphoma: A Single-Center Experience.
Boilève A, Grignano E, Bouscary D, Fourquet A, Deau-Fischer B, Kirova Y
Clin Lymphoma Myeloma Leuk 2021 Jan;21(1):e27-e31. Epub 2020 Aug 22 doi: 10.1016/j.clml.2020.08.015. PMID: 32933880
Contemporary treatment options for a classical disease: Advanced Hodgkin lymphoma.
Reid JH, Marini BL, Nachar VR, Brown AM, Devata S, Perissinotti AJ
Crit Rev Oncol Hematol 2020 Apr;148:102897. Epub 2020 Feb 13 doi: 10.1016/j.critrevonc.2020.102897. PMID: 32109715
Current treatment paradigms for advanced stage Hodgkin lymphoma.
Longley J, Johnson PWM
Br J Haematol 2019 Jan;184(1):60-71. Epub 2018 Nov 8 doi: 10.1111/bjh.15622. PMID: 30408156
Refractory Hodgkin lymphoma.
von Tresckow B, Engert A
Curr Opin Oncol 2013 Sep;25(5):463-9. doi: 10.1097/01.cco.0000432524.62475.60. PMID: 23942291

Therapy

Neutropenia during frontline treatment of advanced Hodgkin lymphoma: Incidence, risk factors, and management.
Sureda A, Domingo-Domenech E, Gautam A
Crit Rev Oncol Hematol 2019 Jun;138:1-5. Epub 2019 Mar 29 doi: 10.1016/j.critrevonc.2019.03.016. PMID: 31092364
PET-adapted therapy for advanced Hodgkin lymphoma - systematic review.
Amitai I, Gurion R, Vidal L, Dann EJ, Raanani P, Gafter-Gvili A
Acta Oncol 2018 Jun;57(6):765-772. Epub 2018 Jan 18 doi: 10.1080/0284186X.2018.1426877. PMID: 29345517
Does Radiation Have a Role in Advanced Stage Hodgkin's or Non-Hodgkin Lymphoma?
Specht L
Curr Treat Options Oncol 2016 Jan;17(1):4. doi: 10.1007/s11864-015-0377-x. PMID: 26739151
Recent advances in Hodgkin lymphoma: interim PET and molecular-targeted therapy.
Nagai H
Jpn J Clin Oncol 2015 Feb;45(2):137-45. Epub 2014 Dec 8 doi: 10.1093/jjco/hyu204. PMID: 25489004
Refractory Hodgkin lymphoma.
von Tresckow B, Engert A
Curr Opin Oncol 2013 Sep;25(5):463-9. doi: 10.1097/01.cco.0000432524.62475.60. PMID: 23942291

Prognosis

Neutropenia during frontline treatment of advanced Hodgkin lymphoma: Incidence, risk factors, and management.
Sureda A, Domingo-Domenech E, Gautam A
Crit Rev Oncol Hematol 2019 Jun;138:1-5. Epub 2019 Mar 29 doi: 10.1016/j.critrevonc.2019.03.016. PMID: 31092364
Current treatment paradigms for advanced stage Hodgkin lymphoma.
Longley J, Johnson PWM
Br J Haematol 2019 Jan;184(1):60-71. Epub 2018 Nov 8 doi: 10.1111/bjh.15622. PMID: 30408156
PET-adapted therapy for advanced Hodgkin lymphoma - systematic review.
Amitai I, Gurion R, Vidal L, Dann EJ, Raanani P, Gafter-Gvili A
Acta Oncol 2018 Jun;57(6):765-772. Epub 2018 Jan 18 doi: 10.1080/0284186X.2018.1426877. PMID: 29345517
Does Radiation Have a Role in Advanced Stage Hodgkin's or Non-Hodgkin Lymphoma?
Specht L
Curr Treat Options Oncol 2016 Jan;17(1):4. doi: 10.1007/s11864-015-0377-x. PMID: 26739151
Refractory Hodgkin lymphoma.
von Tresckow B, Engert A
Curr Opin Oncol 2013 Sep;25(5):463-9. doi: 10.1097/01.cco.0000432524.62475.60. PMID: 23942291

Clinical prediction guides

Decision-Making among Experts in Advanced Hodgkin Lymphoma.
Hitz F, Lang N, Mey U, Mingrone W, Moccia A, Taverna C, Novak U, Stenner F, Schmidt A, Mamot C, Fischer N, Putora PM
Oncology 2023;101(3):159-165. Epub 2022 Sep 27 doi: 10.1159/000526360. PMID: 36103806
Contemporary treatment options for a classical disease: Advanced Hodgkin lymphoma.
Reid JH, Marini BL, Nachar VR, Brown AM, Devata S, Perissinotti AJ
Crit Rev Oncol Hematol 2020 Apr;148:102897. Epub 2020 Feb 13 doi: 10.1016/j.critrevonc.2020.102897. PMID: 32109715
Risk-Adapted Treatment of Advanced Hodgkin Lymphoma With PET-CT.
Lynch RC, Advani RH
Am Soc Clin Oncol Educ Book 2016;35:e376-85. doi: 10.1200/EDBK_159036. PMID: 27249744
Recent advances in Hodgkin lymphoma: interim PET and molecular-targeted therapy.
Nagai H
Jpn J Clin Oncol 2015 Feb;45(2):137-45. Epub 2014 Dec 8 doi: 10.1093/jjco/hyu204. PMID: 25489004
Management of advanced stage Hodgkin lymphoma.
Advani R, Ai WZ, Horning SJ
J Natl Compr Canc Netw 2006 Mar;4(3):241-7. doi: 10.6004/jnccn.2006.0023. PMID: 16507271

Recent systematic reviews

Efficacy and safety of front-line treatments for advanced Hodgkin lymphoma: a systematic literature review.
Dalal M, Gupta J, Price K, Zomas A, Miao H, Ashaye A
Expert Rev Hematol 2020 Aug;13(8):907-922. Epub 2020 Aug 4 doi: 10.1080/17474086.2020.1793666. PMID: 32749937
PET-adapted therapy for advanced Hodgkin lymphoma - systematic review.
Amitai I, Gurion R, Vidal L, Dann EJ, Raanani P, Gafter-Gvili A
Acta Oncol 2018 Jun;57(6):765-772. Epub 2018 Jan 18 doi: 10.1080/0284186X.2018.1426877. PMID: 29345517

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