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Metastatic Acral Lentiginous Melanoma

MedGen UID:
1792122
•Concept ID:
C5555681
•
Neoplastic Process

Definition

Acral lentiginous melanoma that has spread from its original site of growth to another anatomic site. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic Acral Lentiginous Melanoma

Professional guidelines

PubMed

Clinical practice guidelines for the diagnosis and management of melanoma: melanomas that lack classical clinical features.
Mar VJ, Chamberlain AJ, Kelly JW, Murray WK, Thompson JF
Med J Aust 2017 Oct 16;207(8):348-350. doi: 10.5694/mja17.00123. PMID: 29020893
Diagnosis and treatment of malignant melanoma of the foot.
Gray RJ, Pockaj BA, Vega ML, Connolly SM, DiCaudo DJ, Kile TA, Buchel EW
Foot Ankle Int 2006 Sep;27(9):696-705. doi: 10.1177/107110070602700908. PMID: 17038281
Current concepts in the management of patients with melanoma.
Lang PG
Am J Clin Dermatol 2002;3(6):401-26. doi: 10.2165/00128071-200203060-00004. PMID: 12113649

Recent clinical studies

Etiology

Subungual Melanoma: A Single Institution Experience.
LaRocca CJ, Lai L, Nelson RA, Modi B, Crawford B
Med Sci (Basel) 2021 Sep 15;9(3) doi: 10.3390/medsci9030057. PMID: 34564082Free PMC Article
Expression of OPN3 in acral lentiginous melanoma and its associated with clinicohistopathologic features and prognosis.
Zeng W, Zhang W, Feng J, He X, Lu H
Immun Inflamm Dis 2021 Sep;9(3):840-850. Epub 2021 May 6 doi: 10.1002/iid3.438. PMID: 33955704Free PMC Article
Malignant melanoma.
Runkle GP, Zaloznik AJ
Am Fam Physician 1994 Jan;49(1):91-8, 102-4. PMID: 8273727
Acral lentiginous melanoma.
Sutherland CM, Mather FJ, Muchmore JH, Carter RD, Reed RJ, Krementz ET
Am J Surg 1993 Jul;166(1):64-7. doi: 10.1016/s0002-9610(05)80586-0. PMID: 8328633
Nail-bed melanoma.
Klausner JM, Inbar M, Gutman M, Weiss G, Skornick Y, Chaichik S, Rozin RR
J Surg Oncol 1987 Mar;34(3):208-10. doi: 10.1002/jso.2930340317. PMID: 3821128

Diagnosis

Classification and Staging of Melanoma in the Head and Neck.
Bunnell AM, Nedrud SM, Fernandes RP
Oral Maxillofac Surg Clin North Am 2022 May;34(2):221-234. doi: 10.1016/j.coms.2021.12.001. PMID: 35491079
Subungual Melanoma: A Single Institution Experience.
LaRocca CJ, Lai L, Nelson RA, Modi B, Crawford B
Med Sci (Basel) 2021 Sep 15;9(3) doi: 10.3390/medsci9030057. PMID: 34564082Free PMC Article
PRAME Expression in Melanocytic Tumors.
Lezcano C, Jungbluth AA, Nehal KS, Hollmann TJ, Busam KJ
Am J Surg Pathol 2018 Nov;42(11):1456-1465. doi: 10.1097/PAS.0000000000001134. PMID: 30045064Free PMC Article
Malignant melanoma.
Runkle GP, Zaloznik AJ
Am Fam Physician 1994 Jan;49(1):91-8, 102-4. PMID: 8273727
Nail-bed melanoma.
Klausner JM, Inbar M, Gutman M, Weiss G, Skornick Y, Chaichik S, Rozin RR
J Surg Oncol 1987 Mar;34(3):208-10. doi: 10.1002/jso.2930340317. PMID: 3821128

Therapy

Clinical Impact of Immune Checkpoint Inhibitor (ICI) Response, DNA Damage Repair (DDR) Gene Mutations and Immune-Cell Infiltration in Metastatic Melanoma Subtypes.
Andrieu C, McNamee N, Larkin AM, Maguire A, Menon R, Mueller-Eisert J, Horgan N, Kennedy S, Gullo G, Crown J, Walsh N
Med Sci (Basel) 2022 May 24;10(2) doi: 10.3390/medsci10020026. PMID: 35736346Free PMC Article
c-Kit inhibitors for unresectable or metastatic mucosal, acral or chronically sun-damaged melanoma: a systematic review and one-arm meta-analysis.
Steeb T, Wessely A, Petzold A, Kohl C, Erdmann M, Berking C, Heppt MV
Eur J Cancer 2021 Nov;157:348-357. Epub 2021 Sep 22 doi: 10.1016/j.ejca.2021.08.015. PMID: 34562816
Targeted molecular therapy in melanoma.
Puzanov I, Flaherty KT
Semin Cutan Med Surg 2010 Sep;29(3):196-201. doi: 10.1016/j.sder.2010.06.005. PMID: 21051014
Current concepts in the management of patients with melanoma.
Lang PG
Am J Clin Dermatol 2002;3(6):401-26. doi: 10.2165/00128071-200203060-00004. PMID: 12113649
Palliative radiotherapy for recurrent and metastatic malignant melanoma: prognostic factors for tumor response and long-term outcome: a 20-year experience.
Seegenschmiedt MH, Keilholz L, Altendorf-Hofmann A, Urban A, Schell H, Hohenberger W, Sauer R
Int J Radiat Oncol Biol Phys 1999 Jun 1;44(3):607-18. doi: 10.1016/s0360-3016(99)00066-8. PMID: 10348291

Prognosis

Analysis of top-cited articles on melanoma.
Fan KS, Fan KH, Tse PL, Ding H, Su R, Kwok HT
Acta Dermatovenerol Alp Pannonica Adriat 2022 Dec;31(4):127-133. PMID: 36541394
Classification and Staging of Melanoma in the Head and Neck.
Bunnell AM, Nedrud SM, Fernandes RP
Oral Maxillofac Surg Clin North Am 2022 May;34(2):221-234. doi: 10.1016/j.coms.2021.12.001. PMID: 35491079
Malignant melanoma.
Runkle GP, Zaloznik AJ
Am Fam Physician 1994 Jan;49(1):91-8, 102-4. PMID: 8273727
Acral lentiginous melanoma.
Sutherland CM, Mather FJ, Muchmore JH, Carter RD, Reed RJ, Krementz ET
Am J Surg 1993 Jul;166(1):64-7. doi: 10.1016/s0002-9610(05)80586-0. PMID: 8328633
Nail-bed melanoma.
Klausner JM, Inbar M, Gutman M, Weiss G, Skornick Y, Chaichik S, Rozin RR
J Surg Oncol 1987 Mar;34(3):208-10. doi: 10.1002/jso.2930340317. PMID: 3821128

Clinical prediction guides

Classification and Staging of Melanoma in the Head and Neck.
Bunnell AM, Nedrud SM, Fernandes RP
Oral Maxillofac Surg Clin North Am 2022 May;34(2):221-234. doi: 10.1016/j.coms.2021.12.001. PMID: 35491079
Expression of OPN3 in acral lentiginous melanoma and its associated with clinicohistopathologic features and prognosis.
Zeng W, Zhang W, Feng J, He X, Lu H
Immun Inflamm Dis 2021 Sep;9(3):840-850. Epub 2021 May 6 doi: 10.1002/iid3.438. PMID: 33955704Free PMC Article
Prognostic significance of acral lentiginous histologic type in T1 melanoma.
Mejbel HA, Torres-Cabala CA, Milton DR, Ivan D, Feldmeyer L, Namikawa K, Nagarajan P, Tetzlaff MT, Curry JL, Ross MI, Hwu WJ, Prieto VG, Aung PP
Mod Pathol 2021 Mar;34(3):572-583. Epub 2020 Aug 5 doi: 10.1038/s41379-020-0641-x. PMID: 32759976
Current clinical overview of cutaneous melanoma.
Lens M
Br J Nurs 2008 Mar 13-26;17(5):300-5. doi: 10.12968/bjon.2008.17.5.28825. PMID: 18414292
Acral lentiginous melanoma.
Sutherland CM, Mather FJ, Muchmore JH, Carter RD, Reed RJ, Krementz ET
Am J Surg 1993 Jul;166(1):64-7. doi: 10.1016/s0002-9610(05)80586-0. PMID: 8328633

Recent systematic reviews

c-Kit inhibitors for unresectable or metastatic mucosal, acral or chronically sun-damaged melanoma: a systematic review and one-arm meta-analysis.
Steeb T, Wessely A, Petzold A, Kohl C, Erdmann M, Berking C, Heppt MV
Eur J Cancer 2021 Nov;157:348-357. Epub 2021 Sep 22 doi: 10.1016/j.ejca.2021.08.015. PMID: 34562816
Metastatic acral lentiginous melanoma in a tertiary referral center in Switzerland: a systematic analysis.
Häfliger EM, Ramelyte E, Mangana J, Kunz M, Kazakov DV, Dummer R, Cheng PF
Melanoma Res 2018 Oct;28(5):442-450. doi: 10.1097/CMR.0000000000000465. PMID: 29847461

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