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Dendritic cell tumor

MedGen UID:
1842732
•Concept ID:
C5681852
•
Neoplastic Process
Synonyms: dendritic cell neoplasm; dendritic cell tumor
 
Monarch Initiative: MONDO:0020082
Orphanet: ORPHA98289

Definition

A dendritic cell tumor develops from the cells of the immune system. This condition typically begins in the lymph system and may spread to nearby organs or distant parts of the body (metastasize). The symptoms and severity of the condition depend on the subtype and location of the tumor. [from MONDO]

Professional guidelines

PubMed

Development of a Dendritic Cell/Tumor Cell Fusion Cell Membrane Nano-Vaccine for the Treatment of Ovarian Cancer.
Zhang L, Zhao W, Huang J, Li F, Sheng J, Song H, Chen Y
Front Immunol 2022;13:828263. Epub 2022 Feb 17 doi: 10.3389/fimmu.2022.828263. PMID: 35251013Free PMC Article
Follicular dendritic cell tumor in the context of a Castleman disease in a patient with Diffuse Large B Cell Lymphoma: Diagnosis and follow-up with (18)F-FDG PET/CT.
Negre Busó M, Balliu Collgrós E, Ferran Sureda N, Velasco Nuño M, Roncero Vidal JM, Rubió Rodríguez A
Rev Esp Med Nucl Imagen Mol (Engl Ed) 2021 Sep-Oct;40(5):322-324. Epub 2020 Sep 3 doi: 10.1016/j.remnie.2020.08.003. PMID: 34425975
Combined treatment of dendritoma vaccine and low-dose interleukin-2 in stage IV renal cell carcinoma patients induced clinical response: A pilot study.
Wei YC, Sticca RP, Li J, Holmes LM, Burgin KE, Jakubchak S, Bouton-Verville H, Williamson J, Meyer K, Evans L, Martin J, Stephenson JJ, Trocha S, Smith S, Wagner TE
Oncol Rep 2007 Sep;18(3):665-71. PMID: 17671717

Recent clinical studies

Etiology

Descriptive Analysis of Histiocytic and Dendritic Cell Neoplasms: A Single-Institution Experience.
Kim HM, Yang WI, Lyu CJ, Hahn SM, Yoon SO
Yonsei Med J 2020 Sep;61(9):774-779. doi: 10.3349/ymj.2020.61.9.774. PMID: 32882761Free PMC Article
Histiocytic and Dendritic Cell Neoplasms.
Pan Z, Xu ML
Surg Pathol Clin 2019 Sep;12(3):805-829. Epub 2019 Jun 8 doi: 10.1016/j.path.2019.03.013. PMID: 31352989
Cellular Immunotherapy for Hematologic Malignancies: Beyond Bone Marrow Transplantation.
Cirillo M, Tan P, Sturm M, Cole C
Biol Blood Marrow Transplant 2018 Mar;24(3):433-442. Epub 2017 Nov 26 doi: 10.1016/j.bbmt.2017.10.035. PMID: 29102721
Follicular dendritic cell tumor: an aggressive head and neck tumor.
Vargas H, Mouzakes J, Purdy SS, Cohn AS, Parnes SM
Am J Otolaryngol 2002 Mar-Apr;23(2):93-8. doi: 10.1053/ajot.2002.30781. PMID: 11893977
Detection of Epstein-Barr Virus in inflammatory pseudotumor.
Arber DA, Weiss LM, Chang KL
Semin Diagn Pathol 1998 May;15(2):155-60. PMID: 9606806

Diagnosis

Inflammatory Pseudotumor of the Liver.
Wang D, Misdraji J
Surg Pathol Clin 2023 Sep;16(3):565-580. Epub 2023 May 31 doi: 10.1016/j.path.2023.04.010. PMID: 37536889
Follicular dendritic cell sarcoma.
Facchetti F, Simbeni M, Lorenzi L
Pathologica 2021 Oct;113(5):316-329. doi: 10.32074/1591-951X-331. PMID: 34837090Free PMC Article
Histiocytic and Dendritic Cell Neoplasms.
Pan Z, Xu ML
Surg Pathol Clin 2019 Sep;12(3):805-829. Epub 2019 Jun 8 doi: 10.1016/j.path.2019.03.013. PMID: 31352989
Interdigitating dendritic cell sarcoma.
Pokuri VK, Merzianu M, Gandhi S, Baqai J, Loree TR, Bhat S
J Natl Compr Canc Netw 2015 Feb;13(2):128-32. doi: 10.6004/jnccn.2015.0020. PMID: 25691604
Epstein-Barr virus positive inflammatory pseudotumor of the liver: report of a challenging case and review of the literature.
You Y, Shao H, Bui K, Bui M, Klapman J, Cui Q, Coppola D
Ann Clin Lab Sci 2014 Fall;44(4):489-98. PMID: 25361938

Therapy

Vaccine therapy in hematologic malignancies.
Avigan D, Rosenblatt J
Blood 2018 Jun 14;131(24):2640-2650. Epub 2018 May 4 doi: 10.1182/blood-2017-11-785873. PMID: 29728403
Cellular Immunotherapy for Hematologic Malignancies: Beyond Bone Marrow Transplantation.
Cirillo M, Tan P, Sturm M, Cole C
Biol Blood Marrow Transplant 2018 Mar;24(3):433-442. Epub 2017 Nov 26 doi: 10.1016/j.bbmt.2017.10.035. PMID: 29102721
Advances in immunotherapy in multiple myeloma.
Boussi L, Niesvizky R
Curr Opin Oncol 2017 Nov;29(6):460-466. doi: 10.1097/CCO.0000000000000407. PMID: 28877078
Dendritic-cell tumor vaccines.
Rolinski J, Hus I
Transplant Proc 2010 Oct;42(8):3306-8. doi: 10.1016/j.transproceed.2010.07.033. PMID: 20970677
An atypical presentation of a blastic plasmacytoid dendritic cell tumors.
López V, Martí N, Ferrández A, Martin JM, Jordá E
J Cutan Pathol 2010 Sep;37(9):e50-2. Epub 2009 Jul 13 doi: 10.1111/j.1600-0560.2009.01334.x. PMID: 19615025

Prognosis

Histiocytic and Dendritic Cell Neoplasms.
Pan Z, Xu ML
Surg Pathol Clin 2019 Sep;12(3):805-829. Epub 2019 Jun 8 doi: 10.1016/j.path.2019.03.013. PMID: 31352989
Epstein-Barr virus positive inflammatory pseudotumor of the liver: report of a challenging case and review of the literature.
You Y, Shao H, Bui K, Bui M, Klapman J, Cui Q, Coppola D
Ann Clin Lab Sci 2014 Fall;44(4):489-98. PMID: 25361938
Case for diagnosis.
Maio P, Fernandes C, Afonso A, Sachse F, Cabeçadas J, Cardoso J
An Bras Dermatol 2013 Jan-Feb;88(1):131-3. doi: 10.1590/s0365-05962013000100022. PMID: 23539020Free PMC Article
Dendritic-cell tumor vaccines.
Rolinski J, Hus I
Transplant Proc 2010 Oct;42(8):3306-8. doi: 10.1016/j.transproceed.2010.07.033. PMID: 20970677
An atypical presentation of a blastic plasmacytoid dendritic cell tumors.
López V, Martí N, Ferrández A, Martin JM, Jordá E
J Cutan Pathol 2010 Sep;37(9):e50-2. Epub 2009 Jul 13 doi: 10.1111/j.1600-0560.2009.01334.x. PMID: 19615025

Clinical prediction guides

Global trends in tumor microenvironment-related research on tumor vaccine: a review and bibliometric analysis.
Liu Y, Li S, Chen L, Lin L, Xu C, Qiu H, Li X, Cao H, Liu K
Front Immunol 2024;15:1341596. Epub 2024 Feb 6 doi: 10.3389/fimmu.2024.1341596. PMID: 38380323Free PMC Article
Predictors of Response to Autologous Dendritic Cell Therapy in Glioblastoma Multiforme.
Jan CI, Tsai WC, Harn HJ, Shyu WC, Liu MC, Lu HM, Chiu SC, Cho DY
Front Immunol 2018;9:727. Epub 2018 May 29 doi: 10.3389/fimmu.2018.00727. PMID: 29910795Free PMC Article
Vaccine therapy in hematologic malignancies.
Avigan D, Rosenblatt J
Blood 2018 Jun 14;131(24):2640-2650. Epub 2018 May 4 doi: 10.1182/blood-2017-11-785873. PMID: 29728403
Inflammatory Pseudotumor-like Follicular Dendritic Cell Tumor of the Spleen: Case Report and Review of the Literature.
Kitamura Y, Takayama Y, Nishie A, Asayama Y, Ushijima Y, Fujita N, Morita K, Baba S, Kubo Y, Shirabe K, Honda H
Magn Reson Med Sci 2015;14(4):347-54. Epub 2015 Feb 12 doi: 10.2463/mrms.2014-0052. PMID: 25740238
Dendritic cell-tumor fusion vaccines for renal cell carcinoma.
Avigan D
Clin Cancer Res 2004 Sep 15;10(18 Pt 2):6347S-52S. doi: 10.1158/1078-0432.CCR-050005. PMID: 15448029

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