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Benign Lymphatic Vessel Neoplasm

MedGen UID:
224805
•Concept ID:
C1274301
•
Neoplastic Process
Synonyms: Benign Lymph Vessel Neoplasm; Benign Lymph Vessel Tumor; Benign Lymphatic Vessel Tumor; Benign Neoplasm of Lymph Vessel; Benign neoplasm of lymph vessels; Benign Neoplasm of Lymphatic Vessel; Benign Neoplasm of the Lymph Vessel; Benign Neoplasm of the Lymphatic Vessel; Benign Tumor of Lymph Vessel; Benign Tumor of Lymphatic Vessel; Benign Tumor of the Lymph Vessel; Benign Tumor of the Lymphatic Vessel
SNOMED CT: Benign neoplasm of lymph vessels (402868001)

Definition

A benign neoplasm arising from the lymphatic vessels. [from NCI]

Professional guidelines

PubMed

Review of diagnosis, differential diagnosis, and management of retroperitoneal lymphangioma.
Hoang VT, Nguyen MD, Van HAT, Hoang DT
Jpn J Radiol 2023 Mar;41(3):283-301. Epub 2022 Nov 3 doi: 10.1007/s11604-022-01356-0. PMID: 36327088
Overview of primary adult retroperitoneal tumours.
Improta L, Tzanis D, Bouhadiba T, Abdelhafidh K, Bonvalot S
Eur J Surg Oncol 2020 Sep;46(9):1573-1579. Epub 2020 May 21 doi: 10.1016/j.ejso.2020.04.054. PMID: 32600897
A review of the management of lymphangiomas.
Ha J, Yu YC, Lannigan F
Curr Pediatr Rev 2014;10(3):238-48. doi: 10.2174/1573396309666131209210751. PMID: 25088344

Recent clinical studies

Etiology

Large retroperitoneal lymphangioma.
Chiang J, Woo JE, Vu AH, Sirsi S
BMJ Case Rep 2024 May 8;17(5) doi: 10.1136/bcr-2023-258099. PMID: 38719266Free PMC Article
Tuberous Sclerosis: Current Update.
Wang MX, Segaran N, Bhalla S, Pickhardt PJ, Lubner MG, Katabathina VS, Ganeshan D
Radiographics 2021 Nov-Dec;41(7):1992-2010. Epub 2021 Sep 17 doi: 10.1148/rg.2021210103. PMID: 34534018
Renal manifestation of tuberous sclerosis complex.
Bissler JJ, Christopher Kingswood J
Am J Med Genet C Semin Med Genet 2018 Sep;178(3):338-347. Epub 2018 Oct 11 doi: 10.1002/ajmg.c.31654. PMID: 30307110
Childhood cervical lymphadenopathy.
Leung AK, Robson WL
J Pediatr Health Care 2004 Jan-Feb;18(1):3-7. doi: 10.1016/j.pedhc.2003.08.008. PMID: 14722499Free PMC Article
Retroperitoneal cystic lymphangioma.
Nuzzo G, Lemmo G, Marrocco-Trischitta MM, Boldrini G, Giovannini I
J Surg Oncol 1996 Mar;61(3):234-7. doi: 10.1002/(SICI)1096-9098(199603)61:3<234::AID-JSO14>3.0.CO;2-7. PMID: 8637214

Diagnosis

Large retroperitoneal lymphangioma.
Chiang J, Woo JE, Vu AH, Sirsi S
BMJ Case Rep 2024 May 8;17(5) doi: 10.1136/bcr-2023-258099. PMID: 38719266Free PMC Article
Buccal space tumours.
Hasan Z, Tan D, Buchanan M, Palme C, Riffat F
Auris Nasus Larynx 2019 Apr;46(2):160-166. Epub 2018 Jul 18 doi: 10.1016/j.anl.2018.06.011. PMID: 30031665
Pancreatic hemolymphangioma.
Figueroa RM, Lopez GJ, Servin TE, Esquinca MH, Gómez-Pedraza A
JOP 2014 Jul 28;15(4):399-402. doi: 10.6092/1590-8577/2649. PMID: 25076353
Primary nodal hemangioma.
Elgoweini M, Chetty R
Arch Pathol Lab Med 2012 Jan;136(1):110-2. doi: 10.5858/arpa.2010-0687-RS. PMID: 22208495
Splenic vascular tumors.
Kutok JL, Fletcher CD
Semin Diagn Pathol 2003 May;20(2):128-39. doi: 10.1016/s0740-2570(03)00011-x. PMID: 12945936

Therapy

A review of the management of lymphangiomas.
Ha J, Yu YC, Lannigan F
Curr Pediatr Rev 2014;10(3):238-48. doi: 10.2174/1573396309666131209210751. PMID: 25088344
Treatment guidelines of lymphatic malformations of the head and neck.
Zhou Q, Zheng JW, Mai HM, Luo QF, Fan XD, Su LX, Wang YA, Qin ZP
Oral Oncol 2011 Dec;47(12):1105-9. Epub 2011 Sep 8 doi: 10.1016/j.oraloncology.2011.08.001. PMID: 21906990
Giant facial lymphangioma.
Sanger C, Wong L, Wood J, David LR, Argenta LC
J Craniofac Surg 2011 Jul;22(4):1271-4. doi: 10.1097/SCS.0b013e31821c6cf1. PMID: 21772195
Imaging features of lymphangioleiomyomatosis: diagnostic pitfalls.
Avila NA, Dwyer AJ, Moss J
AJR Am J Roentgenol 2011 Apr;196(4):982-6. doi: 10.2214/AJR.10.4185. PMID: 21427352Free PMC Article
Sclerotherapy of lymphangiomas of the head and neck.
Wiegand S, Eivazi B, Zimmermann AP, Sesterhenn AM, Werner JA
Head Neck 2011 Nov;33(11):1649-55. Epub 2010 Aug 24 doi: 10.1002/hed.21552. PMID: 20737487

Prognosis

Intra-abdominal Cystic Lymphangiomas: The Vanderbilt Experience.
Mede A, Chotai PN, Huh WJ, Tan M
J Surg Res 2023 May;285:197-204. Epub 2023 Jan 23 doi: 10.1016/j.jss.2022.12.026. PMID: 36696706
Pancreatic hemolymphangioma.
Figueroa RM, Lopez GJ, Servin TE, Esquinca MH, Gómez-Pedraza A
JOP 2014 Jul 28;15(4):399-402. doi: 10.6092/1590-8577/2649. PMID: 25076353
Splenic vascular tumors.
Kutok JL, Fletcher CD
Semin Diagn Pathol 2003 May;20(2):128-39. doi: 10.1016/s0740-2570(03)00011-x. PMID: 12945936
Angiomyolipoma of kidney.
Eble JN
Semin Diagn Pathol 1998 Feb;15(1):21-40. PMID: 9503504
Retroperitoneal cystic lymphangioma.
Nuzzo G, Lemmo G, Marrocco-Trischitta MM, Boldrini G, Giovannini I
J Surg Oncol 1996 Mar;61(3):234-7. doi: 10.1002/(SICI)1096-9098(199603)61:3<234::AID-JSO14>3.0.CO;2-7. PMID: 8637214

Clinical prediction guides

Benign Orofacial Vascular Anomalies: Review of 47 Cases in Enugu, Nigeria.
Nwoga MC
Niger J Clin Pract 2023 Nov 1;26(11):1723-1727. Epub 2023 Dec 4 doi: 10.4103/njcp.njcp_332_23. PMID: 38044779
A review of the management of lymphangiomas.
Ha J, Yu YC, Lannigan F
Curr Pediatr Rev 2014;10(3):238-48. doi: 10.2174/1573396309666131209210751. PMID: 25088344
Giant facial lymphangioma.
Sanger C, Wong L, Wood J, David LR, Argenta LC
J Craniofac Surg 2011 Jul;22(4):1271-4. doi: 10.1097/SCS.0b013e31821c6cf1. PMID: 21772195
Lymphangioleiomyomatosis: a disease involving the lymphatic system.
Seyama K, Kumasaka T, Kurihara M, Mitani K, Sato T
Lymphat Res Biol 2010 Mar;8(1):21-31. doi: 10.1089/lrb.2009.0018. PMID: 20235884
Micronodular pneumocyte hyperplasia.
Muir TE, Leslie KO, Popper H, Kitaichi M, Gagné E, Emelin JK, Vinters HV, Colby TV
Am J Surg Pathol 1998 Apr;22(4):465-72. doi: 10.1097/00000478-199804000-00012. PMID: 9537475

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