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Brain stem astrocytic neoplasm

MedGen UID:
231458
Concept ID:
C1332608
Neoplastic Process
Synonyms: astrocytoma (excluding glioblastoma) of brainstem; Astrocytoma of brain stem; brain stem astrocytic neoplasm; Brain Stem Astrocytoma; brain stem astrocytoma; Brainstem Astrocytoma; brainstem astrocytoma; brainstem astrocytoma (excluding glioblastoma)
SNOMED CT: Astrocytoma of brain stem (107581000119103)
 
Monarch Initiative: MONDO:0003173

Definition

An astrocytoma that arises from the brain stem. [from NCI]

Professional guidelines

PubMed

Rodríguez-Camacho A, Flores-Vázquez JG, Moscardini-Martelli J, Torres-Ríos JA, Olmos-Guzmán A, Ortiz-Arce CS, Cid-Sánchez DR, Pérez SR, Macías-González MDS, Hernández-Sánchez LC, Heredia-Gutiérrez JC, Contreras-Palafox GA, Suárez-Campos JJE, Celis-López MÁ, Gutiérrez-Aceves GA, Moreno-Jiménez S
Int J Mol Sci 2022 Jun 29;23(13) doi: 10.3390/ijms23137207. PMID: 35806212Free PMC Article
Biserova K, Jakovlevs A, Uljanovs R, Strumfa I
Cells 2021 Mar 11;10(3) doi: 10.3390/cells10030621. PMID: 33799798Free PMC Article
Alifieris C, Trafalis DT
Pharmacol Ther 2015 Aug;152:63-82. Epub 2015 May 2 doi: 10.1016/j.pharmthera.2015.05.005. PMID: 25944528

Recent clinical studies

Etiology

Okonechnikov K, Joshi P, Sepp M, Leiss K, Sarropoulos I, Murat F, Sill M, Beck P, Chan KC, Korshunov A, Sah F, Deng MY, Sturm D, DeSisto J, Donson AM, Foreman NK, Green AL, Robinson G, Orr BA, Gao Q, Darrow E, Hadley JL, Northcott PA, Gojo J, Kawauchi D, Hovestadt V, Filbin MG, von Deimling A, Zuckermann M, Pajtler KW, Kool M, Jones DTW, Jäger N, Kutscher LM, Kaessmann H, Pfister SM
Neuro Oncol 2023 Oct 3;25(10):1895-1909. doi: 10.1093/neuonc/noad124. PMID: 37534924Free PMC Article
Ye Z, Ai X, Yang K, Yang Z, Fei F, Liao X, Qiu Z, Gimple RC, Yuan H, Huang H, Gong Y, Xiao C, Yue J, Huang L, Saulnier O, Wang W, Zhang P, Dai L, Wang X, Wang X, Ahn YH, You C, Xu J, Wan X, Taylor MD, Zhao L, Rich JN, Zhou S
Cancer Discov 2023 Apr 3;13(4):974-1001. doi: 10.1158/2159-8290.CD-22-0455. PMID: 36649564Free PMC Article
Sun Z, Zhao Y, Wei Y, Ding X, Tan C, Wang C
Front Immunol 2022;13:939523. Epub 2022 Aug 25 doi: 10.3389/fimmu.2022.939523. PMID: 36091049Free PMC Article
Le Rhun E, Preusser M, Roth P, Reardon DA, van den Bent M, Wen P, Reifenberger G, Weller M
Cancer Treat Rev 2019 Nov;80:101896. Epub 2019 Sep 11 doi: 10.1016/j.ctrv.2019.101896. PMID: 31541850
Jia D, Li S, Li D, Xue H, Yang D, Liu Y
Aging (Albany NY) 2018 Apr 16;10(4):592-605. doi: 10.18632/aging.101415. PMID: 29676997Free PMC Article

Diagnosis

Gállego Pérez-Larraya J, Garcia-Moure M, Labiano S, Patiño-García A, Dobbs J, Gonzalez-Huarriz M, Zalacain M, Marrodan L, Martinez-Velez N, Puigdelloses M, Laspidea V, Astigarraga I, Lopez-Ibor B, Cruz O, Oscoz Lizarbe M, Hervas-Stubbs S, Alkorta-Aranburu G, Tamayo I, Tavira B, Hernandez-Alcoceba R, Jones C, Dharmadhikari G, Ruiz-Moreno C, Stunnenberg H, Hulleman E, van der Lugt J, Idoate MÁ, Diez-Valle R, Esparragosa Vázquez I, Villalba M, de Andrea C, Núñez-Córdoba JM, Ewald B, Robbins J, Fueyo J, Gomez-Manzano C, Lang FF, Tejada S, Alonso MM
N Engl J Med 2022 Jun 30;386(26):2471-2481. doi: 10.1056/NEJMoa2202028. PMID: 35767439
Salles D, Laviola G, Malinverni ACM, Stávale JN
J Child Neurol 2020 Oct;35(12):852-858. Epub 2020 Jul 20 doi: 10.1177/0883073820937225. PMID: 32691644
Stoyanov GS, Dzhenkov D, Ghenev P, Iliev B, Enchev Y, Tonchev AB
Med Oncol 2018 Jan 31;35(3):27. doi: 10.1007/s12032-018-1083-x. PMID: 29387965
Arribas Alpuente L, Menéndez López A, Yayá Tur R
Clin Transl Oncol 2011 Apr;13(4):240-8. doi: 10.1007/s12094-011-0648-3. PMID: 21493184
Riemenschneider MJ, Reifenberger G
Recent Results Cancer Res 2009;171:3-24. doi: 10.1007/978-3-540-31206-2_1. PMID: 19322535

Therapy

Schaff LR, Mellinghoff IK
JAMA 2023 Feb 21;329(7):574-587. doi: 10.1001/jama.2023.0023. PMID: 36809318
Ye Z, Ai X, Yang K, Yang Z, Fei F, Liao X, Qiu Z, Gimple RC, Yuan H, Huang H, Gong Y, Xiao C, Yue J, Huang L, Saulnier O, Wang W, Zhang P, Dai L, Wang X, Wang X, Ahn YH, You C, Xu J, Wan X, Taylor MD, Zhao L, Rich JN, Zhou S
Cancer Discov 2023 Apr 3;13(4):974-1001. doi: 10.1158/2159-8290.CD-22-0455. PMID: 36649564Free PMC Article
Majzner RG, Ramakrishna S, Yeom KW, Patel S, Chinnasamy H, Schultz LM, Richards RM, Jiang L, Barsan V, Mancusi R, Geraghty AC, Good Z, Mochizuki AY, Gillespie SM, Toland AMS, Mahdi J, Reschke A, Nie EH, Chau IJ, Rotiroti MC, Mount CW, Baggott C, Mavroukakis S, Egeler E, Moon J, Erickson C, Green S, Kunicki M, Fujimoto M, Ehlinger Z, Reynolds W, Kurra S, Warren KE, Prabhu S, Vogel H, Rasmussen L, Cornell TT, Partap S, Fisher PG, Campen CJ, Filbin MG, Grant G, Sahaf B, Davis KL, Feldman SA, Mackall CL, Monje M
Nature 2022 Mar;603(7903):934-941. Epub 2022 Feb 7 doi: 10.1038/s41586-022-04489-4. PMID: 35130560Free PMC Article
Biserova K, Jakovlevs A, Uljanovs R, Strumfa I
Cells 2021 Mar 11;10(3) doi: 10.3390/cells10030621. PMID: 33799798Free PMC Article
Le Rhun E, Preusser M, Roth P, Reardon DA, van den Bent M, Wen P, Reifenberger G, Weller M
Cancer Treat Rev 2019 Nov;80:101896. Epub 2019 Sep 11 doi: 10.1016/j.ctrv.2019.101896. PMID: 31541850

Prognosis

Gállego Pérez-Larraya J, Garcia-Moure M, Labiano S, Patiño-García A, Dobbs J, Gonzalez-Huarriz M, Zalacain M, Marrodan L, Martinez-Velez N, Puigdelloses M, Laspidea V, Astigarraga I, Lopez-Ibor B, Cruz O, Oscoz Lizarbe M, Hervas-Stubbs S, Alkorta-Aranburu G, Tamayo I, Tavira B, Hernandez-Alcoceba R, Jones C, Dharmadhikari G, Ruiz-Moreno C, Stunnenberg H, Hulleman E, van der Lugt J, Idoate MÁ, Diez-Valle R, Esparragosa Vázquez I, Villalba M, de Andrea C, Núñez-Córdoba JM, Ewald B, Robbins J, Fueyo J, Gomez-Manzano C, Lang FF, Tejada S, Alonso MM
N Engl J Med 2022 Jun 30;386(26):2471-2481. doi: 10.1056/NEJMoa2202028. PMID: 35767439
Aldoghachi AF, Aldoghachi AF, Breyne K, Ling KH, Cheah PS
Neuroscience 2022 May 21;491:240-270. Epub 2022 Apr 6 doi: 10.1016/j.neuroscience.2022.03.030. PMID: 35395355
Biserova K, Jakovlevs A, Uljanovs R, Strumfa I
Cells 2021 Mar 11;10(3) doi: 10.3390/cells10030621. PMID: 33799798Free PMC Article
Linkous A, Balamatsias D, Snuderl M, Edwards L, Miyaguchi K, Milner T, Reich B, Cohen-Gould L, Storaska A, Nakayama Y, Schenkein E, Singhania R, Cirigliano S, Magdeldin T, Lin Y, Nanjangud G, Chadalavada K, Pisapia D, Liston C, Fine HA
Cell Rep 2019 Mar 19;26(12):3203-3211.e5. doi: 10.1016/j.celrep.2019.02.063. PMID: 30893594Free PMC Article
Campos B, Olsen LR, Urup T, Poulsen HS
Oncogene 2016 Nov 10;35(45):5819-5825. Epub 2016 Apr 4 doi: 10.1038/onc.2016.85. PMID: 27041580

Clinical prediction guides

Jain S, Rick JW, Joshi RS, Beniwal A, Spatz J, Gill S, Chang AC, Choudhary N, Nguyen AT, Sudhir S, Chalif EJ, Chen JS, Chandra A, Haddad AF, Wadhwa H, Shah SS, Choi S, Hayes JL, Wang L, Yagnik G, Costello JF, Diaz A, Heiland DH, Aghi MK
J Clin Invest 2023 Mar 1;133(5) doi: 10.1172/JCI147087. PMID: 36856115Free PMC Article
Schaff LR, Mellinghoff IK
JAMA 2023 Feb 21;329(7):574-587. doi: 10.1001/jama.2023.0023. PMID: 36809318
Majzner RG, Ramakrishna S, Yeom KW, Patel S, Chinnasamy H, Schultz LM, Richards RM, Jiang L, Barsan V, Mancusi R, Geraghty AC, Good Z, Mochizuki AY, Gillespie SM, Toland AMS, Mahdi J, Reschke A, Nie EH, Chau IJ, Rotiroti MC, Mount CW, Baggott C, Mavroukakis S, Egeler E, Moon J, Erickson C, Green S, Kunicki M, Fujimoto M, Ehlinger Z, Reynolds W, Kurra S, Warren KE, Prabhu S, Vogel H, Rasmussen L, Cornell TT, Partap S, Fisher PG, Campen CJ, Filbin MG, Grant G, Sahaf B, Davis KL, Feldman SA, Mackall CL, Monje M
Nature 2022 Mar;603(7903):934-941. Epub 2022 Feb 7 doi: 10.1038/s41586-022-04489-4. PMID: 35130560Free PMC Article
Salles D, Laviola G, Malinverni ACM, Stávale JN
J Child Neurol 2020 Oct;35(12):852-858. Epub 2020 Jul 20 doi: 10.1177/0883073820937225. PMID: 32691644
Campos B, Olsen LR, Urup T, Poulsen HS
Oncogene 2016 Nov 10;35(45):5819-5825. Epub 2016 Apr 4 doi: 10.1038/onc.2016.85. PMID: 27041580

Recent systematic reviews

Merenzon MA, Hincapie Arias E, Bhatia S, Shah AH, Higgins DMO, Villaverde M, Belgorosky D, Eijan AM
Nitric Oxide 2023 Sep 1;138-139:10-16. Epub 2023 Jun 4 doi: 10.1016/j.niox.2023.06.002. PMID: 37279819
Maddison K, Bowden NA, Graves MC, Tooney PA
BMC Cancer 2023 Feb 23;23(1):185. doi: 10.1186/s12885-023-10659-y. PMID: 36823554Free PMC Article
van Bodegraven EJ, van Asperen JV, Robe PAJ, Hol EM
Glia 2019 Aug;67(8):1417-1433. Epub 2019 Jan 22 doi: 10.1002/glia.23594. PMID: 30667110Free PMC Article
Mahajan-Thakur S, Bien-Möller S, Marx S, Schroeder H, Rauch BH
Int J Mol Sci 2017 Nov 17;18(11) doi: 10.3390/ijms18112448. PMID: 29149079Free PMC Article
Nieder C, Astner ST, Grosu AL
Clin Neurol Neurosurg 2012 Nov;114(9):1207-10. Epub 2012 Apr 18 doi: 10.1016/j.clineuro.2012.03.049. PMID: 22516416

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