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Colorectal Adenoma with Mild Dysplasia

MedGen UID:
232090
Concept ID:
C1333106
Neoplastic Process

Definition

An adenoma that arises from the colon or rectum. It is characterized by the presence of mild epithelial dysplasia. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVColorectal Adenoma with Mild Dysplasia

Professional guidelines

PubMed

Kusunoki M, Hatada T, Sakanoue Y, Yanagi H, Utsunomiya J
Br J Cancer 1992 May;65(5):673-6. doi: 10.1038/bjc.1992.143. PMID: 1586595Free PMC Article

Recent clinical studies

Etiology

Cuche C, Mastrogiovanni M, Juzans M, Laude H, Ungeheuer MN, Krentzel D, Gariboldi MI, Scott-Algara D, Madec M, Goyard S, Floch C, Chauveau-Le Friec G, Lafaye P, Renaudat C, Le Bidan M, Micallef C, Schmutz S, Mella S, Novault S, Hasan M, Duffy D, Di Bartolo V, Alcover A
Front Immunol 2023;14:1163466. Epub 2023 Jul 18 doi: 10.3389/fimmu.2023.1163466. PMID: 37533857Free PMC Article
Qari YA
Niger J Clin Pract 2020 Aug;23(8):1048-1053. doi: 10.4103/njcp.njcp_490_19. PMID: 32788480
Takiyama A, Tanaka T, Kazama S, Nagata H, Kawai K, Hata K, Otani K, Nishikawa T, Sasaki K, Kaneko M, Emoto S, Murono K, Takiyama H, Nozawa H
In Vivo 2018 Mar-Apr;32(2):365-371. doi: 10.21873/invivo.11247. PMID: 29475922Free PMC Article
Ahn JS, Sinn DH, Min YW, Hong SN, Kim HS, Jung SH, Gu S, Rhee PL, Paik SW, Son HJ, Gwak GY
Aliment Pharmacol Ther 2017 Jan;45(2):345-353. Epub 2016 Nov 18 doi: 10.1111/apt.13866. PMID: 27859470
Kim EC, Lance P
Gastroenterol Clin North Am 1997 Mar;26(1):1-17. doi: 10.1016/s0889-8553(05)70280-6. PMID: 9119435

Diagnosis

Takiyama A, Tanaka T, Kazama S, Nagata H, Kawai K, Hata K, Otani K, Nishikawa T, Sasaki K, Kaneko M, Emoto S, Murono K, Takiyama H, Nozawa H
In Vivo 2018 Mar-Apr;32(2):365-371. doi: 10.21873/invivo.11247. PMID: 29475922Free PMC Article
Ahn JS, Sinn DH, Min YW, Hong SN, Kim HS, Jung SH, Gu S, Rhee PL, Paik SW, Son HJ, Gwak GY
Aliment Pharmacol Ther 2017 Jan;45(2):345-353. Epub 2016 Nov 18 doi: 10.1111/apt.13866. PMID: 27859470
Alexandersson BT, Hreinsson JP, Stefansson T, Jonasson JG, Bjornsson ES
Scand J Gastroenterol 2014 May;49(5):576-80. Epub 2014 Mar 13 doi: 10.3109/00365521.2014.886717. PMID: 24621325
Stormorken AT, Clark N, Grindedal E, Maehle L, Møller P
Scand J Gastroenterol 2007 May;42(5):611-7. doi: 10.1080/00365520601010230. PMID: 17454882
Kim EC, Lance P
Gastroenterol Clin North Am 1997 Mar;26(1):1-17. doi: 10.1016/s0889-8553(05)70280-6. PMID: 9119435

Therapy

Groves CJ, Beveridge lG, Swain DJ, Saunders BP, Talbot IC, Nicholls RJ, Phillips RK
Dis Colon Rectum 2005 Apr;48(4):816-23. doi: 10.1007/s10350-004-0835-1. PMID: 15747076
Segnan N, Senore C, Andreoni B, Aste H, Bonelli L, Crosta C, Ferraris R, Gasperoni S, Penna A, Risio M, Rossini FP, Sciallero S, Zappa M, Atkin WS; SCORE Working Group--Italy
J Natl Cancer Inst 2002 Dec 4;94(23):1763-72. doi: 10.1093/jnci/94.23.1763. PMID: 12464648
Atkin WS, Hart A, Edwards R, McIntyre P, Aubrey R, Wardle J, Sutton S, Cuzick J, Northover JM
Gut 1998 Apr;42(4):560-5. doi: 10.1136/gut.42.4.560. PMID: 9616321Free PMC Article
Nakama H, Abdul Fattah AS, Zhang B, Kamijo N, Fujimori K, Miyata K
J Gastroenterol 1997 Aug;32(4):492-5. doi: 10.1007/BF02934088. PMID: 9250896
Karamitopoulou E, Perentes E, Diamantis I, Vogt U, Wegmann W
Histopathology 1995 Dec;27(6):517-23. doi: 10.1111/j.1365-2559.1995.tb00322.x. PMID: 8838331

Prognosis

Alexandersson BT, Hreinsson JP, Stefansson T, Jonasson JG, Bjornsson ES
Scand J Gastroenterol 2014 May;49(5):576-80. Epub 2014 Mar 13 doi: 10.3109/00365521.2014.886717. PMID: 24621325
Stormorken AT, Clark N, Grindedal E, Maehle L, Møller P
Scand J Gastroenterol 2007 May;42(5):611-7. doi: 10.1080/00365520601010230. PMID: 17454882
Li JQ, Wu F, Masaki T, Kubo A, Fujita J, Dixon DA, Beauchamp RD, Ishida T, Kuriyama S, Imaida K
Int J Oncol 2004 Jul;25(1):87-95. PMID: 15201993
Rosandić M, Paar V
Eur J Gastroenterol Hepatol 1998 May;10(5):405-9. doi: 10.1097/00042737-199805000-00009. PMID: 9619387
Kellokumpu I, Husa A
Scand J Gastroenterol 1987 Sep;22(7):833-41. doi: 10.3109/00365528708991923. PMID: 3672041

Clinical prediction guides

Takiyama A, Tanaka T, Kazama S, Nagata H, Kawai K, Hata K, Otani K, Nishikawa T, Sasaki K, Kaneko M, Emoto S, Murono K, Takiyama H, Nozawa H
In Vivo 2018 Mar-Apr;32(2):365-371. doi: 10.21873/invivo.11247. PMID: 29475922Free PMC Article
Wang L, Li D, Liu Y, Wang Y, Cui J, Cui A, Wu W
Tumour Biol 2014 Jun;35(6):6039-46. Epub 2014 Mar 14 doi: 10.1007/s13277-014-1800-9. PMID: 24622886
Stormorken AT, Clark N, Grindedal E, Maehle L, Møller P
Scand J Gastroenterol 2007 May;42(5):611-7. doi: 10.1080/00365520601010230. PMID: 17454882
Rosandić M, Paar V
Eur J Gastroenterol Hepatol 1998 May;10(5):405-9. doi: 10.1097/00042737-199805000-00009. PMID: 9619387
Brown LJ, Smeeton NC, Dixon MF
J Clin Pathol 1985 Feb;38(2):174-9. doi: 10.1136/jcp.38.2.174. PMID: 3968216Free PMC Article

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