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Colorectal Traditional Serrated Adenoma

MedGen UID:
232384
Concept ID:
C1333116
Neoplastic Process
Synonyms: Colorectal Serrated Adenoma; Colorectal Serrated Adenoma Type II; Colorectal TSA; Large Bowel Traditional Serrated Adenoma; Traditional Serrated Adenoma of Large Bowel; Traditional Serrated Adenoma of the Large Bowel

Definition

An adenoma that arises from the colon or rectum. It is characterized by prominent serration of the glands. [from NCI]

Professional guidelines

PubMed

Crockett SD, Nagtegaal ID
Gastroenterology 2019 Oct;157(4):949-966.e4. Epub 2019 Jul 16 doi: 10.1053/j.gastro.2019.06.041. PMID: 31323292
East JE, Atkin WS, Bateman AC, Clark SK, Dolwani S, Ket SN, Leedham SJ, Phull PS, Rutter MD, Shepherd NA, Tomlinson I, Rees CJ
Gut 2017 Jul;66(7):1181-1196. Epub 2017 Apr 27 doi: 10.1136/gutjnl-2017-314005. PMID: 28450390Free PMC Article
Bateman AC, Shepherd NA
J Clin Pathol 2015 Aug;68(8):585-91. Epub 2015 Apr 30 doi: 10.1136/jclinpath-2015-203016. PMID: 25934843

Recent clinical studies

Etiology

Bell PD, Anderson JC, Srivastava A
Am J Surg Pathol 2022 Jan 1;46(1):e64-e70. doi: 10.1097/PAS.0000000000001806. PMID: 34545859
Trovato A, Turshudzhyan A, Tadros M
World J Gastroenterol 2021 Sep 14;27(34):5625-5629. doi: 10.3748/wjg.v27.i34.5625. PMID: 34629791Free PMC Article
He X, Hang D, Wu K, Nayor J, Drew DA, Giovannucci EL, Ogino S, Chan AT, Song M
Gastroenterology 2020 Mar;158(4):852-861.e4. Epub 2019 Jul 11 doi: 10.1053/j.gastro.2019.06.039. PMID: 31302144Free PMC Article
Crockett SD, Nagtegaal ID
Gastroenterology 2019 Oct;157(4):949-966.e4. Epub 2019 Jul 16 doi: 10.1053/j.gastro.2019.06.041. PMID: 31323292
Pai RK, Bettington M, Srivastava A, Rosty C
Mod Pathol 2019 Oct;32(10):1390-1415. Epub 2019 Apr 25 doi: 10.1038/s41379-019-0280-2. PMID: 31028362

Diagnosis

Bell PD, Anderson JC, Srivastava A
Am J Surg Pathol 2022 Jan 1;46(1):e64-e70. doi: 10.1097/PAS.0000000000001806. PMID: 34545859
Sano W, Hirata D, Teramoto A, Iwatate M, Hattori S, Fujita M, Sano Y
World J Gastroenterol 2020 May 21;26(19):2276-2285. doi: 10.3748/wjg.v26.i19.2276. PMID: 32476792Free PMC Article
He X, Hang D, Wu K, Nayor J, Drew DA, Giovannucci EL, Ogino S, Chan AT, Song M
Gastroenterology 2020 Mar;158(4):852-861.e4. Epub 2019 Jul 11 doi: 10.1053/j.gastro.2019.06.039. PMID: 31302144Free PMC Article
Pai RK, Bettington M, Srivastava A, Rosty C
Mod Pathol 2019 Oct;32(10):1390-1415. Epub 2019 Apr 25 doi: 10.1038/s41379-019-0280-2. PMID: 31028362
Chetty R
J Clin Pathol 2016 Jan;69(1):6-11. Epub 2015 Nov 9 doi: 10.1136/jclinpath-2015-203452. PMID: 26553935

Therapy

Ni M, Zhang Y, Sun Z, Zhou Q, Xiao J, Zhang B, Lin J, Gong B, Liu F, Meng F, Zheng G, Wang Y, Gu L, Li L, Shen W, Chen Y, Liu Y, Li L, Ling T, Cheng H
Phytomedicine 2024 May;127:155496. Epub 2024 Feb 27 doi: 10.1016/j.phymed.2024.155496. PMID: 38471368
Harpaz N, Goldblum JR, Shepherd NA, Riddell RH, Rubio CA, Vieth M, Wang HH, Odze RD
Hum Pathol 2023 Aug;138:49-61. Epub 2023 May 27 doi: 10.1016/j.humpath.2023.05.008. PMID: 37247824
Shah S, Park N, Chehade NEH, Chahine A, Monachese M, Tiritilli A, Moosvi Z, Ortizo R, Samarasena J
J Gastroenterol Hepatol 2023 Feb;38(2):162-176. Epub 2022 Dec 11 doi: 10.1111/jgh.16059. PMID: 36350048
Tsai JH, Jeng YM, Yuan CT, Lin YL, Cheng ML, Liau JY
Am J Surg Pathol 2019 Aug;43(8):1042-1051. doi: 10.1097/PAS.0000000000001274. PMID: 31094930
Hafezi-Bakhtiari S, Wang LM, Colling R, Serra S, Chetty R
Histopathology 2015 Jan;66(2):308-13. Epub 2014 Nov 13 doi: 10.1111/his.12555. PMID: 25257227

Prognosis

Bell PD, Anderson JC, Srivastava A
Am J Surg Pathol 2022 Jan 1;46(1):e64-e70. doi: 10.1097/PAS.0000000000001806. PMID: 34545859
He X, Hang D, Wu K, Nayor J, Drew DA, Giovannucci EL, Ogino S, Chan AT, Song M
Gastroenterology 2020 Mar;158(4):852-861.e4. Epub 2019 Jul 11 doi: 10.1053/j.gastro.2019.06.039. PMID: 31302144Free PMC Article
Crockett SD, Nagtegaal ID
Gastroenterology 2019 Oct;157(4):949-966.e4. Epub 2019 Jul 16 doi: 10.1053/j.gastro.2019.06.041. PMID: 31323292
Chetty R
J Clin Pathol 2016 Jan;69(1):6-11. Epub 2015 Nov 9 doi: 10.1136/jclinpath-2015-203452. PMID: 26553935
Bettington ML, Chetty R
Hum Pathol 2015 Jul;46(7):933-8. Epub 2015 Apr 20 doi: 10.1016/j.humpath.2015.04.002. PMID: 26001333

Clinical prediction guides

Zhou YJ, Lu XF, Chen H, Wang XY, Cheng W, Zhang QW, Chen JN, Wang XY, Jin JZ, Yan FR, Chen H, Li XB
Cell Mol Gastroenterol Hepatol 2023;15(2):393-424. Epub 2022 Oct 8 doi: 10.1016/j.jcmgh.2022.10.001. PMID: 36216310Free PMC Article
Bell PD, Anderson JC, Srivastava A
Am J Surg Pathol 2022 Jan 1;46(1):e64-e70. doi: 10.1097/PAS.0000000000001806. PMID: 34545859
Trovato A, Turshudzhyan A, Tadros M
World J Gastroenterol 2021 Sep 14;27(34):5625-5629. doi: 10.3748/wjg.v27.i34.5625. PMID: 34629791Free PMC Article
Chetty R
J Clin Pathol 2016 Jan;69(1):6-11. Epub 2015 Nov 9 doi: 10.1136/jclinpath-2015-203452. PMID: 26553935
Bettington ML, Chetty R
Hum Pathol 2015 Jul;46(7):933-8. Epub 2015 Apr 20 doi: 10.1016/j.humpath.2015.04.002. PMID: 26001333

Recent systematic reviews

Shah S, Park N, Chehade NEH, Chahine A, Monachese M, Tiritilli A, Moosvi Z, Ortizo R, Samarasena J
J Gastroenterol Hepatol 2023 Feb;38(2):162-176. Epub 2022 Dec 11 doi: 10.1111/jgh.16059. PMID: 36350048
Lin X, You F, Liu H, Fang Y, Jin S, Wang Q
PLoS One 2021;16(1):e0245921. Epub 2021 Jan 25 doi: 10.1371/journal.pone.0245921. PMID: 33493235Free PMC Article
Aziz M, Fatima R, Lee-Smith W, Khuder S, Nawras A
Eur J Gastroenterol Hepatol 2020 Oct;32(10):1284-1292. doi: 10.1097/MEG.0000000000001844. PMID: 32773510
Travaglino A, D'Armiento FP, Cassese G, Campanino MR, Borrelli G, Pignatiello S, Luglio G, Maione F, De Palma GD, D'Armiento M
Histopathology 2019 Aug;75(2):160-173. Epub 2019 May 16 doi: 10.1111/his.13846. PMID: 30815911

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