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Soft tissue chondroma

MedGen UID:
266157
•Concept ID:
C1275277
•
Neoplastic Process
Synonyms: Chondroma of Soft Parts; chondroma of soft parts; Extraskeletal Chondroma; extraskeletal chondroma; Extraskeletal Osteochondroma; extraskeletal osteochondroma; Soft Tissue Chondroma; soft tissue chondroma
SNOMED CT: Soft tissue chondroma (404078000)
 
Monarch Initiative: MONDO:0006423

Definition

A benign neoplasm arising from the extraskeletal soft tissues near tendons and joints. It is a well circumscribed tumor characterized by the presence of chondrocytes, a lobulated hyaline cartilage growth pattern, and in some cases calcification. [from NCI]

Professional guidelines

PubMed

MR imaging of the forefoot: Morton neuroma and differential diagnoses.
Zanetti M, Weishaupt D
Semin Musculoskelet Radiol 2005 Sep;9(3):175-86. doi: 10.1055/s-2005-921938. PMID: 16247719

Recent clinical studies

Therapy

Rare case of bladder chondroma causing lower urinary tract symptoms.
Ngweso S, Mukhtar S, Forrest C, Mander J
BMJ Case Rep 2019 Jan 18;12(1) doi: 10.1136/bcr-2018-227006. PMID: 30661043Free PMC Article
Cytogenetic findings in 14 benign cartilaginous neoplasms.
Sakai Junior N, Abe KT, Formigli LM, Pereira MF, de Oliveira MD, Cornelio DA, de La Roque Ferreira A, Kalil RK
Cancer Genet 2011 Apr;204(4):180-6. doi: 10.1016/j.cancergen.2011.02.004. PMID: 21536235
Correlation between clinicopathological features and karyotype in 100 cartilaginous and chordoid tumours. A report from the Chromosomes and Morphology (CHAMP) Collaborative Study Group.
Tallini G, Dorfman H, Brys P, Dal Cin P, De Wever I, Fletcher CD, Jonson K, Mandahl N, Mertens F, Mitelman F, Rosai J, Rydholm A, Samson I, Sciot R, Van den Berghe H, Vanni R, Willén H
J Pathol 2002 Feb;196(2):194-203. doi: 10.1002/path.1023. PMID: 11793371

Prognosis

ERG expression in chondrogenic bone and soft tissue tumours.
Shon W, Folpe AL, Fritchie KJ
J Clin Pathol 2015 Feb;68(2):125-9. Epub 2014 Nov 5 doi: 10.1136/jclinpath-2014-202601. PMID: 25378537
A case of congenital soft tissue chondroma.
Ryu JH, Park EJ, Kim KH, Kim KJ
J Dermatol 2005 Mar;32(3):214-6. doi: 10.1111/j.1346-8138.2005.tb00748.x. PMID: 15863870
Correlation between clinicopathological features and karyotype in 100 cartilaginous and chordoid tumours. A report from the Chromosomes and Morphology (CHAMP) Collaborative Study Group.
Tallini G, Dorfman H, Brys P, Dal Cin P, De Wever I, Fletcher CD, Jonson K, Mandahl N, Mertens F, Mitelman F, Rosai J, Rydholm A, Samson I, Sciot R, Van den Berghe H, Vanni R, Willén H
J Pathol 2002 Feb;196(2):194-203. doi: 10.1002/path.1023. PMID: 11793371

Clinical prediction guides

Imaging characteristics of slow-growing soft tissue chondroma of the tongue: A case report.
Park Y, Kim HY, Yu IK, Jang DS, Kim JH
Medicine (Baltimore) 2022 May 13;101(19):e29276. doi: 10.1097/MD.0000000000029276. PMID: 35583538Free PMC Article
Soft-Tissue Chondroma in the Right Hallux: A Case Report.
Hao X, Yim J, Qi C, Mirkin G
J Am Podiatr Med Assoc 2019 Nov;109(6):451-454. doi: 10.7547/18-047. PMID: 31755773
Synovial chondromatosis and soft tissue chondroma: extraosseous cartilaginous tumor defined by FN1 gene rearrangement.
Amary F, Perez-Casanova L, Ye H, Cottone L, Strobl AC, Cool P, Miranda E, Berisha F, Aston W, Rocha M, O'Donnell P, Pillay N, Tirabosco R, Baumhoer D, Hookway ES, Flanagan AM
Mod Pathol 2019 Dec;32(12):1762-1771. Epub 2019 Jul 4 doi: 10.1038/s41379-019-0315-8. PMID: 31273315Free PMC Article
Soft Tissue Chondroma of the Eyelid.
Aseem F, Pace ST, Onajin O, Sangueza OP, Yeatts RP
Ophthalmic Plast Reconstr Surg 2018 Sep/Oct;34(5):e168-e170. doi: 10.1097/IOP.0000000000001199. PMID: 30124612
ERG expression in chondrogenic bone and soft tissue tumours.
Shon W, Folpe AL, Fritchie KJ
J Clin Pathol 2015 Feb;68(2):125-9. Epub 2014 Nov 5 doi: 10.1136/jclinpath-2014-202601. PMID: 25378537

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