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High Grade Anal Canal Intraepithelial Neoplasia

MedGen UID:
272717
•Concept ID:
C1334009
•
Neoplastic Process
Synonyms: High Grade Anal Canal Dysplasia; High Grade Anal Canal Squamous Dysplasia; High Grade Anal Canal Squamous Intraepithelial Neoplasia; High Grade Anal Squamous Intraepithelial Neoplasia

Definition

Intraepithelial neoplasia involving the anal canal. The epithelial cells exhibit moderate dysplasia (grade II intraepithelial neoplasia) or severe dysplasia (grade III intraepithelial neoplasia or carcinoma in situ). [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHigh Grade Anal Canal Intraepithelial Neoplasia

Professional guidelines

PubMed

Anal intraepithelial neoplasia: a review of terminology, differential diagnoses, and patient management.
Vyas M, Gonzalez RS
Hum Pathol 2023 Feb;132:56-64. Epub 2022 Jul 16 doi: 10.1016/j.humpath.2022.07.005. PMID: 35843339
Prevalence of anal dysplasia and HPV genotypes in gynecology patients: The ANGY cross-sectional prospective clinical study protocol.
Pache B, Balaya V, Mathis J, Hübner M, Sahli R, Cavassini M, Sempoux C, Mathevet P, Jacot-Guillarmod M
PLoS One 2022;17(10):e0276438. Epub 2022 Oct 21 doi: 10.1371/journal.pone.0276438. PMID: 36269726Free PMC Article
The reporting of anal cytology and histology samples: establishing terminology and criteria.
Roberts JM, Ekman D
Sex Health 2012 Dec;9(6):562-7. doi: 10.1071/SH10140. PMID: 22951231

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