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Testicular trophoblastic tumor

MedGen UID:
272844
Concept ID:
C1515301
Neoplastic Process
Synonyms: Testicular Trophoblastic Tumor; testicular trophoblastic tumor
 
Monarch Initiative: MONDO:0002871

Definition

A tumor that arises from the testis and is composed of neoplastic trophoblastic cells. The vast majority of cases are choriocarcinomas. [from NCI]

Professional guidelines

PubMed

Rougemont AL, Tille JC
Hum Pathol 2018 Nov;81:26-36. Epub 2018 May 16 doi: 10.1016/j.humpath.2018.04.025. PMID: 29753846
Reilley MJ, Pagliaro LC
Curr Oncol Rep 2015 Feb;17(2):2. doi: 10.1007/s11912-014-0430-0. PMID: 25645112
Takizawa A, Kishida T, Miura T, Hattori Y, Noguchi K, Kubota Y
J Urol 2008 Mar;179(3):930-4; discussion 934-5. Epub 2008 Jan 22 doi: 10.1016/j.juro.2007.11.008. PMID: 18207192

Recent clinical studies

Etiology

Nome RV, Bjøro T, Paus E, Bjerner J, Fosså SD, Steen R, Nustad K, Bolstad N
Clin Biochem 2018 Feb;52:73-79. Epub 2017 Dec 2 doi: 10.1016/j.clinbiochem.2017.11.016. PMID: 29198759
Mego M, Cierna Z, Svetlovska D, Macak D, Machalekova K, Miskovska V, Chovanec M, Usakova V, Obertova J, Babal P, Mardiak J
J Clin Pathol 2013 Jul;66(7):607-12. Epub 2013 Mar 13 doi: 10.1136/jclinpath-2012-201088. PMID: 23486608
Cole LA
Reprod Biol Endocrinol 2009 Jan 26;7:8. doi: 10.1186/1477-7827-7-8. PMID: 19171054Free PMC Article
Talerman A
Ann Pathol 1985;5(3):145-57. PMID: 3000396
Frei E 3rd
Cancer Res 1985 Dec;45(12 Pt 1):6523-37. PMID: 2998603

Diagnosis

Batool A, Liu XM, Zhang CL, Hao CF, Chen SR, Liu YX
Front Biosci (Landmark Ed) 2019 Mar 1;24(4):765-776. doi: 10.2741/4749. PMID: 30844711
Reilley MJ, Pagliaro LC
Curr Oncol Rep 2015 Feb;17(2):2. doi: 10.1007/s11912-014-0430-0. PMID: 25645112
Stenman UH, Alfthan H, Hotakainen K
Clin Biochem 2004 Jul;37(7):549-61. doi: 10.1016/j.clinbiochem.2004.05.008. PMID: 15234236
Talerman A
Ann Pathol 1985;5(3):145-57. PMID: 3000396
Krone KD, Carroll BA
Radiol Clin North Am 1985 Mar;23(1):121-39. PMID: 2858113

Therapy

Yang XY, Bégin LR, Tamaz R
Gastroenterology 2022 Jan;162(1):e14-e15. Epub 2021 Jun 17 doi: 10.1053/j.gastro.2021.05.065. PMID: 34146570
Reilley MJ, Pagliaro LC
Curr Oncol Rep 2015 Feb;17(2):2. doi: 10.1007/s11912-014-0430-0. PMID: 25645112
Lester SG, Morphis JG 2nd, Hornback NB, Williams SD, Einhorn LH
J Clin Oncol 1984 Dec;2(12):1397-403. doi: 10.1200/JCO.1984.2.12.1397. PMID: 6210350
Heiken JP, Balfe DM, McClennan BL
Int J Radiat Oncol Biol Phys 1984 Feb;10(2):275-87. doi: 10.1016/0360-3016(84)90014-2. PMID: 6200463
Hainsworth JD, Greco FA
Am J Med 1983 Nov;75(5):817-32. doi: 10.1016/0002-9343(83)90413-8. PMID: 6195919

Prognosis

Batool A, Liu XM, Zhang CL, Hao CF, Chen SR, Liu YX
Front Biosci (Landmark Ed) 2019 Mar 1;24(4):765-776. doi: 10.2741/4749. PMID: 30844711
Reilley MJ, Pagliaro LC
Curr Oncol Rep 2015 Feb;17(2):2. doi: 10.1007/s11912-014-0430-0. PMID: 25645112
Cole LA
Reprod Biol Endocrinol 2009 Jan 26;7:8. doi: 10.1186/1477-7827-7-8. PMID: 19171054Free PMC Article
Stenman UH, Alfthan H, Hotakainen K
Clin Biochem 2004 Jul;37(7):549-61. doi: 10.1016/j.clinbiochem.2004.05.008. PMID: 15234236
Therman E, Sarto GE, Stubblefield PA
Hum Genet 1983;63(1):13-8. doi: 10.1007/BF00285390. PMID: 6187660

Clinical prediction guides

Mego M, Cierna Z, Svetlovska D, Macak D, Machalekova K, Miskovska V, Chovanec M, Usakova V, Obertova J, Babal P, Mardiak J
J Clin Pathol 2013 Jul;66(7):607-12. Epub 2013 Mar 13 doi: 10.1136/jclinpath-2012-201088. PMID: 23486608
Cole LA
Reprod Biol Endocrinol 2009 Jan 26;7:8. doi: 10.1186/1477-7827-7-8. PMID: 19171054Free PMC Article
Stenman UH, Alfthan H, Hotakainen K
Clin Biochem 2004 Jul;37(7):549-61. doi: 10.1016/j.clinbiochem.2004.05.008. PMID: 15234236
Talerman A
Ann Pathol 1985;5(3):145-57. PMID: 3000396
Therman E, Sarto GE, Stubblefield PA
Hum Genet 1983;63(1):13-8. doi: 10.1007/BF00285390. PMID: 6187660

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