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Salivary gland mucoepidermoid carcinoma

MedGen UID:
277630
Concept ID:
C1335903
Neoplastic Process
Synonyms: Mucoepidermoid carcinoma of salivary gland; Mucoepidermoid Carcinoma of Salivary Gland; mucoepidermoid carcinoma of salivary gland; Mucoepidermoid Carcinoma of the Salivary Gland; mucoepidermoid carcinoma of the salivary gland; saliva-secreting gland mucoepidermoid carcinoma; Salivary Gland Mucoepidermoid Carcinoma; salivary gland mucoepidermoid carcinoma
SNOMED CT: Mucoepidermoid carcinoma of salivary gland (423708008)
 
Monarch Initiative: MONDO:0021009

Definition

A carcinoma that arises from the salivary glands. It is the most common primary carcinoma of the salivary glands and usually presents as a firm and painless mass. It is characterized by the presence of squamous cells, mucus producing cells, and cells of intermediate type. The majority of cases have a favorable outcome. [from NCI]

Professional guidelines

PubMed

Goode RK, Auclair PL, Ellis GL
Cancer 1998 Apr 1;82(7):1217-24. doi: 10.1002/(sici)1097-0142(19980401)82:7<1217::aid-cncr2>3.0.co;2-c. PMID: 9529011

Recent clinical studies

Etiology

Li Y, Hu C
Eur Arch Otorhinolaryngol 2023 Aug;280(8):3835-3841. Epub 2023 Apr 26 doi: 10.1007/s00405-023-07963-5. PMID: 37100896
Abdolrahmani A, Kardouni Khoozestani N, Azmoudeh-Ardalan F, Shamshiri AR
Head Neck Pathol 2022 Dec;16(4):1134-1145. Epub 2022 Aug 18 doi: 10.1007/s12105-022-01475-0. PMID: 35980523Free PMC Article
Okumura Y, Nakano S, Murase T, Ueda K, Kawakita D, Nagao T, Kusafuka K, Urano M, Yamamoto H, Kano S, Tsukahara K, Okami K, Nagao T, Hanai N, Iwai H, Kawata R, Tada Y, Nibu KI, Inagaki H
Cancer Sci 2020 Nov;111(11):4195-4204. Epub 2020 Sep 14 doi: 10.1111/cas.14632. PMID: 32860299Free PMC Article
Nikolic N, Carkic J, Ilic Dimitrijevic I, Eljabo N, Radunovic M, Anicic B, Tanic N, Falk M, Milasin J
Oral Surg Oral Med Oral Pathol Oral Radiol 2018 Jan;125(1):52-58. Epub 2017 Sep 28 doi: 10.1016/j.oooo.2017.09.013. PMID: 29079368
Patel TD, Vázquez A, Patel DM, Baredes S, Eloy JA
Int Forum Allergy Rhinol 2015 Jan;5(1):78-84. Epub 2014 Oct 20 doi: 10.1002/alr.21422. PMID: 25332187

Diagnosis

Urumarudappa SKJ, Tran VNT, Oo HM, Suntiparpluacha M, Sampattavanich S, Rosa V, Ruangritchankul K, Ferreira JN, Chaisuparat R
J Oral Pathol Med 2023 Nov;52(10):939-950. Epub 2023 Sep 27 doi: 10.1111/jop.13488. PMID: 37756121
Li Y, Hu C
Eur Arch Otorhinolaryngol 2023 Aug;280(8):3835-3841. Epub 2023 Apr 26 doi: 10.1007/s00405-023-07963-5. PMID: 37100896
Robinson L, van Heerden MB, Ker-Fox JG, Hunter KD, van Heerden WFP
Head Neck Pathol 2021 Jun;15(2):491-502. Epub 2020 Sep 21 doi: 10.1007/s12105-020-01226-z. PMID: 32959209Free PMC Article
Salem A, Bell D, Sepesi B, Papadimitrakopoulou V, El-Naggar A, Moran CA, Kalhor N
Virchows Arch 2017 Jun;470(6):619-626. Epub 2017 Mar 25 doi: 10.1007/s00428-017-2104-4. PMID: 28343305
Patel TD, Vázquez A, Patel DM, Baredes S, Eloy JA
Int Forum Allergy Rhinol 2015 Jan;5(1):78-84. Epub 2014 Oct 20 doi: 10.1002/alr.21422. PMID: 25332187

Prognosis

Urumarudappa SKJ, Tran VNT, Oo HM, Suntiparpluacha M, Sampattavanich S, Rosa V, Ruangritchankul K, Ferreira JN, Chaisuparat R
J Oral Pathol Med 2023 Nov;52(10):939-950. Epub 2023 Sep 27 doi: 10.1111/jop.13488. PMID: 37756121
Li Y, Hu C
Eur Arch Otorhinolaryngol 2023 Aug;280(8):3835-3841. Epub 2023 Apr 26 doi: 10.1007/s00405-023-07963-5. PMID: 37100896
Abdolrahmani A, Kardouni Khoozestani N, Azmoudeh-Ardalan F, Shamshiri AR
Head Neck Pathol 2022 Dec;16(4):1134-1145. Epub 2022 Aug 18 doi: 10.1007/s12105-022-01475-0. PMID: 35980523Free PMC Article
Robinson L, van Heerden MB, Ker-Fox JG, Hunter KD, van Heerden WFP
Head Neck Pathol 2021 Jun;15(2):491-502. Epub 2020 Sep 21 doi: 10.1007/s12105-020-01226-z. PMID: 32959209Free PMC Article
Shah AA, La Fortune K, Miller C, Mills SE, Baloch Z, LiVolsi V, Dacic S, Mahaffey AL, Nikiforova M, Nikiforov YE, Seethala RR
Mod Pathol 2017 Mar;30(3):329-339. Epub 2016 Dec 2 doi: 10.1038/modpathol.2016.180. PMID: 27910944Free PMC Article

Clinical prediction guides

Urumarudappa SKJ, Tran VNT, Oo HM, Suntiparpluacha M, Sampattavanich S, Rosa V, Ruangritchankul K, Ferreira JN, Chaisuparat R
J Oral Pathol Med 2023 Nov;52(10):939-950. Epub 2023 Sep 27 doi: 10.1111/jop.13488. PMID: 37756121
Abdolrahmani A, Kardouni Khoozestani N, Azmoudeh-Ardalan F, Shamshiri AR
Head Neck Pathol 2022 Dec;16(4):1134-1145. Epub 2022 Aug 18 doi: 10.1007/s12105-022-01475-0. PMID: 35980523Free PMC Article
Andrade NP, Warner KA, Zhang Z, Pearson AT, Mantesso A, Guimaraēs DM, Altemani A, Mariano FV, Nunes FD, Nör JE
Cell Death Dis 2021 Jan 21;12(1):108. doi: 10.1038/s41419-021-03391-7. PMID: 33479203Free PMC Article
Nakano T, Warner KA, Oklejas AE, Zhang Z, Rodriguez-Ramirez C, Shuman AG, Nör JE
J Dent Res 2021 Apr;100(4):377-386. Epub 2020 Oct 17 doi: 10.1177/0022034520965141. PMID: 33073679Free PMC Article
Robinson L, van Heerden MB, Ker-Fox JG, Hunter KD, van Heerden WFP
Head Neck Pathol 2021 Jun;15(2):491-502. Epub 2020 Sep 21 doi: 10.1007/s12105-020-01226-z. PMID: 32959209Free PMC Article

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