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Colorectal squamous cell carcinoma

MedGen UID:
317527
•Concept ID:
C1707442
•
Neoplastic Process
Synonyms: colorectal (colon or rectal) squamous cell cancer; colorectal squamous cell cancer; Colorectal Squamous Cell Carcinoma; colorectal squamous cell carcinoma; colorectum squamous cell carcinoma
 
Monarch Initiative: MONDO:0006165

Definition

A very rare colorectal carcinoma characterized by the presence of a malignant squamous cell infiltrate. [from NCI]

Professional guidelines

PubMed

A systematic and comprehensive analysis of colorectal squamous cell carcinoma: Implication for diagnosis and treatment.
Yang Y, Yu J, Hu J, Zhou C, Niu J, Ma H, Han J, Fan S, Liu Y, Zhao Y, Zhao L, Wang G
Cancer Med 2022 Jun;11(12):2492-2502. Epub 2022 Feb 23 doi: 10.1002/cam4.4616. PMID: 35194959Free PMC Article

Recent clinical studies

Etiology

Colorectal squamous cell carcinoma: a rare tumor with poor prognosis.
Ozuner G, Aytac E, Gorgun E, Bennett A
Int J Colorectal Dis 2015 Jan;30(1):127-30. Epub 2014 Nov 13 doi: 10.1007/s00384-014-2058-9. PMID: 25392258
Role of human papillomavirus in squamous cell metaplasia-dysplasia-carcinoma of the rectum.
Kong CS, Welton ML, Longacre TA
Am J Surg Pathol 2007 Jun;31(6):919-25. doi: 10.1097/01.pas.0000213441.86030.fc. PMID: 17527081

Diagnosis

A systematic and comprehensive analysis of colorectal squamous cell carcinoma: Implication for diagnosis and treatment.
Yang Y, Yu J, Hu J, Zhou C, Niu J, Ma H, Han J, Fan S, Liu Y, Zhao Y, Zhao L, Wang G
Cancer Med 2022 Jun;11(12):2492-2502. Epub 2022 Feb 23 doi: 10.1002/cam4.4616. PMID: 35194959Free PMC Article
Primary Squamous Cell Carcinoma of Colon and Rectum: A Systematic Review of the Literature.
Schizas D, Katsaros I, Mastoraki A, Karela NR, Zampetaki D, Lazaridis II, Tsapralis D, Theodoropoulos GE
J Invest Surg 2022 Jan;35(1):151-156. Epub 2020 Oct 6 doi: 10.1080/08941939.2020.1824044. PMID: 33021125
Diagnostically challenging human papillomavirus-associated primary squamous cell carcinoma of the rectum with metastasis in both ovaries: a case report.
Tschann P, Lechner D, Feurstein B, Abendstein B, Dertinger S, Bösl A, Vitlarov N, Offner F, Königsrainer I
J Med Case Rep 2020 Feb 14;14(1):30. doi: 10.1186/s13256-020-2348-5. PMID: 32054542Free PMC Article
Colorectal squamous cell carcinoma: a rare tumor with poor prognosis.
Ozuner G, Aytac E, Gorgun E, Bennett A
Int J Colorectal Dis 2015 Jan;30(1):127-30. Epub 2014 Nov 13 doi: 10.1007/s00384-014-2058-9. PMID: 25392258

Prognosis

A systematic and comprehensive analysis of colorectal squamous cell carcinoma: Implication for diagnosis and treatment.
Yang Y, Yu J, Hu J, Zhou C, Niu J, Ma H, Han J, Fan S, Liu Y, Zhao Y, Zhao L, Wang G
Cancer Med 2022 Jun;11(12):2492-2502. Epub 2022 Feb 23 doi: 10.1002/cam4.4616. PMID: 35194959Free PMC Article
Colorectal squamous cell carcinoma: a rare tumor with poor prognosis.
Ozuner G, Aytac E, Gorgun E, Bennett A
Int J Colorectal Dis 2015 Jan;30(1):127-30. Epub 2014 Nov 13 doi: 10.1007/s00384-014-2058-9. PMID: 25392258

Clinical prediction guides

A systematic and comprehensive analysis of colorectal squamous cell carcinoma: Implication for diagnosis and treatment.
Yang Y, Yu J, Hu J, Zhou C, Niu J, Ma H, Han J, Fan S, Liu Y, Zhao Y, Zhao L, Wang G
Cancer Med 2022 Jun;11(12):2492-2502. Epub 2022 Feb 23 doi: 10.1002/cam4.4616. PMID: 35194959Free PMC Article
Squamous metaplasia in colorectal polyps.
Almagro UA, Pintar K, Zellmer RB
Cancer 1984 Jun 15;53(12):2679-82. doi: 10.1002/1097-0142(19840615)53:12<2679::aid-cncr2820531219>3.0.co;2-6. PMID: 6722726

Recent systematic reviews

Primary Squamous Cell Carcinoma of Colon and Rectum: A Systematic Review of the Literature.
Schizas D, Katsaros I, Mastoraki A, Karela NR, Zampetaki D, Lazaridis II, Tsapralis D, Theodoropoulos GE
J Invest Surg 2022 Jan;35(1):151-156. Epub 2020 Oct 6 doi: 10.1080/08941939.2020.1824044. PMID: 33021125

Supplemental Content

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