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Cardiac valve calcification

MedGen UID:
383924
•Concept ID:
C1856483
•
Finding
Synonym: Calcifications of the cardiac valves
 
HPO: HP:0005146

Definition

Abnormal calcification of a cardiac valve. [from HPO]

Professional guidelines

PubMed

Inherited Arterial Calcification Syndromes: Etiologies and Treatment Concepts.
Nitschke Y, Rutsch F
Curr Osteoporos Rep 2017 Aug;15(4):255-270. doi: 10.1007/s11914-017-0370-3. PMID: 28585220
Medical management of secondary hyperparathyroidism in chronic renal failure.
Goodman WG
Nephrol Dial Transplant 2003 Jun;18 Suppl 3:iii2-8. doi: 10.1093/ndt/gfg1002. PMID: 12771290

Recent clinical studies

Etiology

Progression of Vascular Calcification and Clinical Outcomes in Patients Receiving Maintenance Dialysis.
Zhang H, Li G, Yu X, Yang J, Jiang A, Cheng H, Fu J, Liang X, Liu J, Lou J, Wang M, Xing C, Zhang A, Zhang M, Xiao X, Yu C, Wang R, Wang L, Chen Y, Guan T, Peng A, Chen N, Hao C, Liu B, Wang S, Shen D, Jia Z, Liu Z; China Dialysis Calcification Study Group
JAMA Netw Open 2023 May 1;6(5):e2310909. doi: 10.1001/jamanetworkopen.2023.10909. PMID: 37126347Free PMC Article
Hyperphosphatemia is associated with cardiac valve calcification in chronic hypoparathyroidism.
Polonine S, de Santa Rosa RG, Farias MLF, Garcia MI, Gomes CP, Gottlieb I, Madeira M
J Endocrinol Invest 2022 Jul;45(7):1359-1366. Epub 2022 Mar 2 doi: 10.1007/s40618-022-01770-1. PMID: 35235195
Cardiac valve calcification and risk of cardiovascular or all-cause mortality in dialysis patients: a meta-analysis.
Wang Z, Jiang A, Wei F, Chen H
BMC Cardiovasc Disord 2018 Jan 25;18(1):12. doi: 10.1186/s12872-018-0747-y. PMID: 29370754Free PMC Article
Inherited Arterial Calcification Syndromes: Etiologies and Treatment Concepts.
Nitschke Y, Rutsch F
Curr Osteoporos Rep 2017 Aug;15(4):255-270. doi: 10.1007/s11914-017-0370-3. PMID: 28585220
Vascular calcification.
Christian RC, Fitzpatrick LA
Curr Opin Nephrol Hypertens 1999 Jul;8(4):443-8. doi: 10.1097/00041552-199907000-00008. PMID: 10491739

Diagnosis

Progression of Vascular Calcification and Clinical Outcomes in Patients Receiving Maintenance Dialysis.
Zhang H, Li G, Yu X, Yang J, Jiang A, Cheng H, Fu J, Liang X, Liu J, Lou J, Wang M, Xing C, Zhang A, Zhang M, Xiao X, Yu C, Wang R, Wang L, Chen Y, Guan T, Peng A, Chen N, Hao C, Liu B, Wang S, Shen D, Jia Z, Liu Z; China Dialysis Calcification Study Group
JAMA Netw Open 2023 May 1;6(5):e2310909. doi: 10.1001/jamanetworkopen.2023.10909. PMID: 37126347Free PMC Article
Cardiac valve calcification prevalence and association with neutrophil-to-lymphocyte ratio in newly diagnosed patients with non-dialysis chronic kidney disease stage 3-5.
Li B, Hu X, Pan H, Xiao Y, Dong J, Bao Y, Fang M
Bratisl Lek Listy 2022;123(7):523-527. doi: 10.4149/BLL_2022_084. PMID: 35907060
Correlation between Serum Magnesium Level and Cardiac Valve Calcification in Patients with Chronic Kidney Disease.
Ding Z, Chen W, Zhang C, Wang H, Ma X
Clin Lab 2022 Apr 1;68(4) doi: 10.7754/Clin.Lab.2021.210533. PMID: 35443599
Hyperphosphatemia is associated with cardiac valve calcification in chronic hypoparathyroidism.
Polonine S, de Santa Rosa RG, Farias MLF, Garcia MI, Gomes CP, Gottlieb I, Madeira M
J Endocrinol Invest 2022 Jul;45(7):1359-1366. Epub 2022 Mar 2 doi: 10.1007/s40618-022-01770-1. PMID: 35235195
Cardiac valve calcification and risk of cardiovascular or all-cause mortality in dialysis patients: a meta-analysis.
Wang Z, Jiang A, Wei F, Chen H
BMC Cardiovasc Disord 2018 Jan 25;18(1):12. doi: 10.1186/s12872-018-0747-y. PMID: 29370754Free PMC Article

Therapy

Progression of Vascular Calcification and Clinical Outcomes in Patients Receiving Maintenance Dialysis.
Zhang H, Li G, Yu X, Yang J, Jiang A, Cheng H, Fu J, Liang X, Liu J, Lou J, Wang M, Xing C, Zhang A, Zhang M, Xiao X, Yu C, Wang R, Wang L, Chen Y, Guan T, Peng A, Chen N, Hao C, Liu B, Wang S, Shen D, Jia Z, Liu Z; China Dialysis Calcification Study Group
JAMA Netw Open 2023 May 1;6(5):e2310909. doi: 10.1001/jamanetworkopen.2023.10909. PMID: 37126347Free PMC Article
Serum Alkaline Phosphatase Level Predicts Cardiac Valve Calcification in Maintenance Hemodialysis Patients.
Guo J, Zeng M, Zhang Y, Huang H, Yang G, Xu F, Ren W, Wang J, Huang Y, Wang N, Xing C
Blood Purif 2020;49(5):550-559. Epub 2020 Feb 12 doi: 10.1159/000505846. PMID: 32050204
Cardiac valve calcification and use of anticoagulants: Preliminary observation of a potentially modifiable risk factor.
Di Lullo L, Tripepi G, Ronco C, D'Arrigo G, Barbera V, Russo D, Di Iorio BR, Uguccioni M, Paoletti E, Ravera M, Fusaro M, Bellasi A
Int J Cardiol 2019 Mar 1;278:243-249. Epub 2018 Nov 29 doi: 10.1016/j.ijcard.2018.11.119. PMID: 30538058
Cardiac valve calcification and risk of cardiovascular or all-cause mortality in dialysis patients: a meta-analysis.
Wang Z, Jiang A, Wei F, Chen H
BMC Cardiovasc Disord 2018 Jan 25;18(1):12. doi: 10.1186/s12872-018-0747-y. PMID: 29370754Free PMC Article
Vascular calcification.
Christian RC, Fitzpatrick LA
Curr Opin Nephrol Hypertens 1999 Jul;8(4):443-8. doi: 10.1097/00041552-199907000-00008. PMID: 10491739

Prognosis

Cardiac valve calcification prevalence and association with neutrophil-to-lymphocyte ratio in newly diagnosed patients with non-dialysis chronic kidney disease stage 3-5.
Li B, Hu X, Pan H, Xiao Y, Dong J, Bao Y, Fang M
Bratisl Lek Listy 2022;123(7):523-527. doi: 10.4149/BLL_2022_084. PMID: 35907060
Hyperphosphatemia is associated with cardiac valve calcification in chronic hypoparathyroidism.
Polonine S, de Santa Rosa RG, Farias MLF, Garcia MI, Gomes CP, Gottlieb I, Madeira M
J Endocrinol Invest 2022 Jul;45(7):1359-1366. Epub 2022 Mar 2 doi: 10.1007/s40618-022-01770-1. PMID: 35235195
Serum Alkaline Phosphatase Level Predicts Cardiac Valve Calcification in Maintenance Hemodialysis Patients.
Guo J, Zeng M, Zhang Y, Huang H, Yang G, Xu F, Ren W, Wang J, Huang Y, Wang N, Xing C
Blood Purif 2020;49(5):550-559. Epub 2020 Feb 12 doi: 10.1159/000505846. PMID: 32050204
Cardiac valve calcification and use of anticoagulants: Preliminary observation of a potentially modifiable risk factor.
Di Lullo L, Tripepi G, Ronco C, D'Arrigo G, Barbera V, Russo D, Di Iorio BR, Uguccioni M, Paoletti E, Ravera M, Fusaro M, Bellasi A
Int J Cardiol 2019 Mar 1;278:243-249. Epub 2018 Nov 29 doi: 10.1016/j.ijcard.2018.11.119. PMID: 30538058
Cardiac valve calcification and risk of cardiovascular or all-cause mortality in dialysis patients: a meta-analysis.
Wang Z, Jiang A, Wei F, Chen H
BMC Cardiovasc Disord 2018 Jan 25;18(1):12. doi: 10.1186/s12872-018-0747-y. PMID: 29370754Free PMC Article

Clinical prediction guides

Progression of Vascular Calcification and Clinical Outcomes in Patients Receiving Maintenance Dialysis.
Zhang H, Li G, Yu X, Yang J, Jiang A, Cheng H, Fu J, Liang X, Liu J, Lou J, Wang M, Xing C, Zhang A, Zhang M, Xiao X, Yu C, Wang R, Wang L, Chen Y, Guan T, Peng A, Chen N, Hao C, Liu B, Wang S, Shen D, Jia Z, Liu Z; China Dialysis Calcification Study Group
JAMA Netw Open 2023 May 1;6(5):e2310909. doi: 10.1001/jamanetworkopen.2023.10909. PMID: 37126347Free PMC Article
Cardiac valve calcification prevalence and association with neutrophil-to-lymphocyte ratio in newly diagnosed patients with non-dialysis chronic kidney disease stage 3-5.
Li B, Hu X, Pan H, Xiao Y, Dong J, Bao Y, Fang M
Bratisl Lek Listy 2022;123(7):523-527. doi: 10.4149/BLL_2022_084. PMID: 35907060
Correlation between Serum Magnesium Level and Cardiac Valve Calcification in Patients with Chronic Kidney Disease.
Ding Z, Chen W, Zhang C, Wang H, Ma X
Clin Lab 2022 Apr 1;68(4) doi: 10.7754/Clin.Lab.2021.210533. PMID: 35443599
Hyperphosphatemia is associated with cardiac valve calcification in chronic hypoparathyroidism.
Polonine S, de Santa Rosa RG, Farias MLF, Garcia MI, Gomes CP, Gottlieb I, Madeira M
J Endocrinol Invest 2022 Jul;45(7):1359-1366. Epub 2022 Mar 2 doi: 10.1007/s40618-022-01770-1. PMID: 35235195
Vascular calcification.
Christian RC, Fitzpatrick LA
Curr Opin Nephrol Hypertens 1999 Jul;8(4):443-8. doi: 10.1097/00041552-199907000-00008. PMID: 10491739

Recent systematic reviews

Role of emodin in atherosclerosis and other cardiovascular diseases: Pharmacological effects, mechanisms, and potential therapeutic target as a phytochemical.
Wang X, Yang S, Li Y, Jin X, Lu J, Wu M
Biomed Pharmacother 2023 May;161:114539. Epub 2023 Mar 17 doi: 10.1016/j.biopha.2023.114539. PMID: 36933375

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