U.S. flag

An official website of the United States government


Send to:

Choose Destination

Autosomal recessive nonsyndromic hearing loss 63(DFNB63)

MedGen UID:
Concept ID:
Disease or Syndrome
Synonyms: Deafness, autosomal recessive 63; DFNB63 Nonsyndromic Hearing Loss and Deafness
Gene (location): LRTOMT (11q13.4)
Monarch Initiative: MONDO:0012670
OMIM®: 611451


Any autosomal recessive nonsyndromic deafness in which the cause of the disease is a mutation in the LRTOMT gene. [from MONDO]

Clinical features

From HPO
Abnormal vestibular function
MedGen UID:
Concept ID:
An abnormality of the functioning of the vestibular apparatus.
Congenital sensorineural hearing impairment
MedGen UID:
Concept ID:
Disease or Syndrome
A type of hearing impairment caused by an abnormal functionality of the cochlear nerve with congenital onset.
Abnormal fundus morphology
MedGen UID:
Concept ID:
Anatomical Abnormality
Any structural abnormality of the fundus of the eye.

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  

Recent clinical studies


Vallian Broojeni J, Kazemi A, Rezaei H, Vallian S
PLoS One 2023;18(8):e0289247. Epub 2023 Aug 10 doi: 10.1371/journal.pone.0289247. PMID: 37561809Free PMC Article
Prasad S, Kölln KA, Cucci RA, Trembath RC, Van Camp G, Smith RJ
Am J Med Genet A 2004 Jan 1;124A(1):1-9. doi: 10.1002/ajmg.a.20272. PMID: 14679580

Clinical prediction guides

Dodson KM, Blanton SH, Welch KO, Norris VW, Nuzzo RL, Wegelin JA, Marin RS, Nance WE, Pandya A, Arnos KS
Am J Med Genet A 2011 May;155A(5):993-1000. Epub 2011 Apr 4 doi: 10.1002/ajmg.a.33828. PMID: 21465647Free PMC Article

Supplemental Content

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...