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Neovascularization

MedGen UID:
45041
Concept ID:
C0027686
Pathologic Function
Synonyms: Angiogenesis, Pathologic; Angiogenesis, Pathological; Neovascularization, Pathologic; Neovascularization, Pathological; Pathologic Angiogenesis; Pathologic Neovascularization; Pathological Angiogenesis; Pathological Neovascularization
SNOMED CT: Neovascularization (13018008); Neovascularity (13018008); Vascularization (13018008)

Definition

The formation of new or recent blood vessels. The vasculature network is critical to the development of neoplasms. As the tumor burden grows, vascular endothelial cells are recruited to form new blood vessels as an increased demand for blood and nourishment is required. [from NCI]

Professional guidelines

PubMed

Flores R, Carneiro Â, Vieira M, Tenreiro S, Seabra MC
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J Eur Acad Dermatol Venereol 2018 Apr;32(4):564-569. Epub 2017 Dec 21 doi: 10.1111/jdv.14722. PMID: 29194786

Recent clinical studies

Etiology

Wigner P, Grębowski R, Bijak M, Saluk-Bijak J, Szemraj J
Int J Mol Sci 2021 Apr 25;22(9) doi: 10.3390/ijms22094483. PMID: 33923108Free PMC Article
Ebrahimiadib N, Maleki A, Fadakar K, Manhapra A, Ghassemi F, Foster CS
Surv Ophthalmol 2021 Jul-Aug;66(4):653-667. Epub 2021 Jan 5 doi: 10.1016/j.survophthal.2020.12.006. PMID: 33412171
Sharif Z, Sharif W
Rom J Ophthalmol 2019 Jan-Mar;63(1):15-22. PMID: 31198893Free PMC Article
Ruiz-Casado A, Martín-Ruiz A, Pérez LM, Provencio M, Fiuza-Luces C, Lucia A
Trends Cancer 2017 Jun;3(6):423-441. Epub 2017 Jun 3 doi: 10.1016/j.trecan.2017.04.007. PMID: 28718417
Hippe A, Homey B, Mueller-Homey A
Recent Results Cancer Res 2010;180:35-50. doi: 10.1007/978-3-540-78281-0_4. PMID: 20033377

Diagnosis

Nicholas MP, Mysore N
Exp Eye Res 2021 Jan;202:108363. Epub 2020 Nov 19 doi: 10.1016/j.exer.2020.108363. PMID: 33221371
Sharif Z, Sharif W
Rom J Ophthalmol 2019 Jan-Mar;63(1):15-22. PMID: 31198893Free PMC Article
Summerhill V, Orekhov A
Adv Exp Med Biol 2019;1147:279-297. doi: 10.1007/978-3-030-16908-4_13. PMID: 31147883
Bergeron C, Al-Ramli W, Hamid Q
Proc Am Thorac Soc 2009 May 1;6(3):301-5. doi: 10.1513/pats.200808-089RM. PMID: 19387034
Voravud N, Charuruk N
J Med Assoc Thai 1999 Apr;82(4):394-404. PMID: 10410503

Therapy

Hayreh SS
Prog Retin Eye Res 2021 Nov;85:100964. Epub 2021 Mar 11 doi: 10.1016/j.preteyeres.2021.100964. PMID: 33713810
Olejarz W, Kubiak-Tomaszewska G, Chrzanowska A, Lorenc T
Int J Mol Sci 2020 Aug 14;21(16) doi: 10.3390/ijms21165840. PMID: 32823989Free PMC Article
Garcia J, Hurwitz HI, Sandler AB, Miles D, Coleman RL, Deurloo R, Chinot OL
Cancer Treat Rev 2020 Jun;86:102017. Epub 2020 Mar 26 doi: 10.1016/j.ctrv.2020.102017. PMID: 32335505
Todorova D, Simoncini S, Lacroix R, Sabatier F, Dignat-George F
Circ Res 2017 May 12;120(10):1658-1673. doi: 10.1161/CIRCRESAHA.117.309681. PMID: 28495996Free PMC Article
Camaré C, Pucelle M, Nègre-Salvayre A, Salvayre R
Redox Biol 2017 Aug;12:18-34. Epub 2017 Feb 1 doi: 10.1016/j.redox.2017.01.007. PMID: 28212521Free PMC Article

Prognosis

Iorga ER, Costin D
Rom J Ophthalmol 2020 Oct-Dec;64(4):323-332. doi: 10.22336/rjo.2020.54. PMID: 33367170Free PMC Article
Ikuno Y
Retina 2017 Dec;37(12):2347-2351. doi: 10.1097/IAE.0000000000001489. PMID: 28590964
Tsai ASH, Cheung N, Gan ATL, Jaffe GJ, Sivaprasad S, Wong TY, Cheung CMG
Surv Ophthalmol 2017 Jul-Aug;62(4):462-492. Epub 2017 Feb 9 doi: 10.1016/j.survophthal.2017.01.008. PMID: 28189495
Foster PJ, Jiang Y
Eye (Lond) 2014 Feb;28(2):202-8. Epub 2014 Jan 10 doi: 10.1038/eye.2013.280. PMID: 24406412Free PMC Article
Donati MB
Haemostasis 1994 Mar-Apr;24(2):128-31. doi: 10.1159/000217092. PMID: 7959360

Clinical prediction guides

Lin WP, Xing KL, Fu JC, Ling YH, Li SH, Yu WS, Zhang YF, Zhong C, Wang JH, Chen ZY, Lu LH, Wei W, Guo RP
JAMA Netw Open 2021 Sep 1;4(9):e2125055. doi: 10.1001/jamanetworkopen.2021.25055. PMID: 34515782Free PMC Article
Zhang Y, Cao J, Zhou J, Zhang C, Li Q, Chen S, Feinstein S, Grayburn PA, Huang P
Eur J Vasc Endovasc Surg 2021 Sep;62(3):358-366. doi: 10.1016/j.ejvs.2021.05.026. PMID: 34266763
Ohno-Matsui K, Kawasaki R, Jonas JB, Cheung CM, Saw SM, Verhoeven VJ, Klaver CC, Moriyama M, Shinohara K, Kawasaki Y, Yamazaki M, Meuer S, Ishibashi T, Yasuda M, Yamashita H, Sugano A, Wang JJ, Mitchell P, Wong TY; META-analysis for Pathologic Myopia (META-PM) Study Group
Am J Ophthalmol 2015 May;159(5):877-83.e7. Epub 2015 Jan 26 doi: 10.1016/j.ajo.2015.01.022. PMID: 25634530
Koole D, Heyligers J, Moll FL, Pasterkamp G
J Cardiovasc Med (Hagerstown) 2012 Oct;13(10):635-9. doi: 10.2459/JCM.0b013e3283590cd2. PMID: 22955205
Wykrzykowska JJ, Henry TD, Lesser JR, Schwartz RS
Nat Rev Cardiol 2009 Oct;6(10):648-58. Epub 2009 Sep 8 doi: 10.1038/nrcardio.2009.157. PMID: 19736553

Recent systematic reviews

Kirnaz S, Capadona C, Wong T, Goldberg JL, Medary B, Sommer F, McGrath LB Jr, Härtl R
World Neurosurg 2022 Jan;157:264-273. doi: 10.1016/j.wneu.2021.09.066. PMID: 34929784
De Wolde SD, Hulskes RH, Weenink RP, Hollmann MW, Van Hulst RA
Biomolecules 2021 Aug 14;11(8) doi: 10.3390/biom11081210. PMID: 34439876Free PMC Article
Eramo S, Natali A, Pinna R, Milia E
Int Endod J 2018 Apr;51(4):405-419. Epub 2017 Nov 7 doi: 10.1111/iej.12868. PMID: 29047120
Gheorghe A, Mahdi L, Musat O
Rom J Ophthalmol 2015 Apr-Jun;59(2):74-7. PMID: 26978865Free PMC Article
Terelak-Borys B, Skonieczna K, Grabska-Liberek I
Med Sci Monit 2012 Aug;18(8):RA138-144. doi: 10.12659/msm.883260. PMID: 22847215Free PMC Article

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