U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Dermatitis, atopic, 9(ATOD9)

MedGen UID:
462114
•Concept ID:
C3150764
•
Disease or Syndrome
Synonyms: ATOD9; DERMATITIS, ATOPIC, 9
 
Monarch Initiative: MONDO:0013295
OMIM®: 613519

Definition

An inherited susceptibility or predisposition to developing atopic dermatitis that is associated with variation in the region 3p24. [from MONDO]

Professional guidelines

PubMed

European guideline (EuroGuiDerm) on atopic eczema: part I - systemic therapy.
Wollenberg A, Kinberger M, Arents B, Aszodi N, Avila Valle G, Barbarot S, Bieber T, Brough HA, Calzavara Pinton P, Christen-Zäch S, Deleuran M, Dittmann M, Dressler C, Fink-Wagner AH, Fosse N, Gáspár K, Gerbens L, Gieler U, Girolomoni G, Gregoriou S, Mortz CG, Nast A, Nygaard U, Redding M, Rehbinder EM, Ring J, Rossi M, Serra-Baldrich E, Simon D, Szalai ZZ, Szepietowski JC, Torrelo A, Werfel T, Flohr C
J Eur Acad Dermatol Venereol 2022 Sep;36(9):1409-1431. doi: 10.1111/jdv.18345. PMID: 35980214
Biological treatment in allergic disease.
Shamji MH, Palmer E, Layhadi JA, Moraes TJ, Eiwegger T
Allergy 2021 Sep;76(9):2934-2937. Epub 2021 Jun 12 doi: 10.1111/all.14954. PMID: 34028048
Eosinophilic Dermatoses: Recognition and Management.
Marzano AV, Genovese G
Am J Clin Dermatol 2020 Aug;21(4):525-539. doi: 10.1007/s40257-020-00520-4. PMID: 32394361

Recent clinical studies

Etiology

Children atopic dermatitis: Diagnosis, mimics, overlaps, and therapeutic implication.
Napolitano M, Fabbrocini G, Martora F, Genco L, Noto M, Patruno C
Dermatol Ther 2022 Dec;35(12):e15901. Epub 2022 Oct 13 doi: 10.1111/dth.15901. PMID: 36200594Free PMC Article
Efficacy and safety of abrocitinib versus dupilumab in adults with moderate-to-severe atopic dermatitis: a randomised, double-blind, multicentre phase 3 trial.
Reich K, Thyssen JP, Blauvelt A, Eyerich K, Soong W, Rice ZP, Hong HC, Katoh N, Valenzuela F, DiBonaventura M, Bratt TA, Zhang F, Clibborn C, Rojo R, Valdez H, Kerkmann U
Lancet 2022 Jul 23;400(10348):273-282. doi: 10.1016/S0140-6736(22)01199-0. PMID: 35871814
Comparative efficacy and safety of abrocitinib, baricitinib, and upadacitinib for moderate-to-severe atopic dermatitis: A network meta-analysis.
Wan H, Jia H, Xia T, Zhang D
Dermatol Ther 2022 Sep;35(9):e15636. Epub 2022 Jul 27 doi: 10.1111/dth.15636. PMID: 35703351Free PMC Article
An update on current pharmacotherapy options in atopic dermatitis.
Reitamo S, Remitz A
Expert Opin Pharmacother 2014 Aug;15(11):1517-24. Epub 2014 May 8 doi: 10.1517/14656566.2014.915941. PMID: 24811606
Atopic dermatitis.
Beltrani VS, Boguneiwicz M
Dermatol Online J 2003 Mar;9(2):1. PMID: 12639454

Diagnosis

Children atopic dermatitis: Diagnosis, mimics, overlaps, and therapeutic implication.
Napolitano M, Fabbrocini G, Martora F, Genco L, Noto M, Patruno C
Dermatol Ther 2022 Dec;35(12):e15901. Epub 2022 Oct 13 doi: 10.1111/dth.15901. PMID: 36200594Free PMC Article
Atopic Dermatitis: Aiming for Total Disease Control.
Arruda LK, Koplin JJ
J Allergy Clin Immunol Pract 2021 Apr;9(4):1508-1509. doi: 10.1016/j.jaip.2021.02.030. PMID: 33838841
Treat-to-Target in Atopic Dermatitis: An International Consensus on a Set of Core Decision Points for Systemic Therapies.
De Bruin-Weller M, Biedermann T, Bissonnette R, Deleuran M, Foley P, Girolomoni G, Hercogová J, Hong CH, Katoh N, Pink AE, Richard MA, Shumack S, Silvestre JF, Weidinger S
Acta Derm Venereol 2021 Feb 17;101(2):adv00402. doi: 10.2340/00015555-3751. PMID: 33491094Free PMC Article
Update on Atopic Dermatitis.
Torres T, Ferreira EO, Gonçalo M, Mendes-Bastos P, Selores M, Filipe P
Acta Med Port 2019 Sep 2;32(9):606-613. doi: 10.20344/amp.11963. PMID: 31493365
Atopic dermatitis.
Beltrani VS, Boguneiwicz M
Dermatol Online J 2003 Mar;9(2):1. PMID: 12639454

Therapy

Efficacy and safety of abrocitinib versus dupilumab in adults with moderate-to-severe atopic dermatitis: a randomised, double-blind, multicentre phase 3 trial.
Reich K, Thyssen JP, Blauvelt A, Eyerich K, Soong W, Rice ZP, Hong HC, Katoh N, Valenzuela F, DiBonaventura M, Bratt TA, Zhang F, Clibborn C, Rojo R, Valdez H, Kerkmann U
Lancet 2022 Jul 23;400(10348):273-282. doi: 10.1016/S0140-6736(22)01199-0. PMID: 35871814
Comparative efficacy and safety of abrocitinib, baricitinib, and upadacitinib for moderate-to-severe atopic dermatitis: A network meta-analysis.
Wan H, Jia H, Xia T, Zhang D
Dermatol Ther 2022 Sep;35(9):e15636. Epub 2022 Jul 27 doi: 10.1111/dth.15636. PMID: 35703351Free PMC Article
What is the most effective systemic treatment for atopic dermatitis?
Banerjee N, Grewal A
Clin Exp Allergy 2021 Sep;51(9):1103-1106. Epub 2021 Jul 8 doi: 10.1111/cea.13980. PMID: 34197666
Neonatal scabies.
Camassa F, Fania M, Ditano G, Silvestris AM, Lomuto M
Cutis 1995 Oct;56(4):210-2. PMID: 8575219
Plant-induced dermatitis.
Epstein WL
Ann Emerg Med 1987 Sep;16(9):950-5. doi: 10.1016/s0196-0644(87)80739-4. PMID: 3307555

Prognosis

Global epidemiology of atopic dermatitis: a comprehensive systematic analysis and modelling study.
Tian J, Zhang D, Yang Y, Huang Y, Wang L, Yao X, Lu Q
Br J Dermatol 2023 Dec 20;190(1):55-61. doi: 10.1093/bjd/ljad339. PMID: 37705227
Children atopic dermatitis: Diagnosis, mimics, overlaps, and therapeutic implication.
Napolitano M, Fabbrocini G, Martora F, Genco L, Noto M, Patruno C
Dermatol Ther 2022 Dec;35(12):e15901. Epub 2022 Oct 13 doi: 10.1111/dth.15901. PMID: 36200594Free PMC Article
Prevalence and Incidence of Atopic Dermatitis: A Systematic Review.
Bylund S, Kobyletzki LB, Svalstedt M, Svensson Å
Acta Derm Venereol 2020 Jun 9;100(12):adv00160. doi: 10.2340/00015555-3510. PMID: 32412646Free PMC Article
Update on Atopic Dermatitis.
Torres T, Ferreira EO, Gonçalo M, Mendes-Bastos P, Selores M, Filipe P
Acta Med Port 2019 Sep 2;32(9):606-613. doi: 10.20344/amp.11963. PMID: 31493365
Neonatal scabies.
Camassa F, Fania M, Ditano G, Silvestris AM, Lomuto M
Cutis 1995 Oct;56(4):210-2. PMID: 8575219

Clinical prediction guides

Rapid pruritus reduction with ruxolitinib cream treatment in patients with atopic dermatitis.
Blauvelt A, Kircik L, Papp KA, Simpson EL, Silverberg JI, Kim BS, Kwatra SG, Kuligowski ME, Venturanza ME, Wei S, Szepietowski JC
J Eur Acad Dermatol Venereol 2023 Jan;37(1):137-146. Epub 2022 Sep 21 doi: 10.1111/jdv.18571. PMID: 36066323Free PMC Article
Long-Term Efficacy and Safety of Dupilumab in Adolescents with Moderate-to-Severe Atopic Dermatitis: Results Through Week 52 from a Phase III Open-Label Extension Trial (LIBERTY AD PED-OLE).
Blauvelt A, Guttman-Yassky E, Paller AS, Simpson EL, Cork MJ, Weisman J, Browning J, Soong W, Sun X, Chen Z, Kosloski MP, Kamal MA, Delevry D, Chuang CC, O'Malley JT, Bansal A
Am J Clin Dermatol 2022 May;23(3):365-383. Epub 2022 May 14 doi: 10.1007/s40257-022-00683-2. PMID: 35567671Free PMC Article
Systemic Immunomodulatory Treatments for Atopic Dermatitis: Update of a Living Systematic Review and Network Meta-analysis.
Drucker AM, Morra DE, Prieto-Merino D, Ellis AG, Yiu ZZN, Rochwerg B, Di Giorgio S, Arents BWM, Burton T, Spuls PI, Schmitt J, Flohr C
JAMA Dermatol 2022 May 1;158(5):523-532. doi: 10.1001/jamadermatol.2022.0455. PMID: 35293977Free PMC Article
Epidemiology of atopic dermatitis in adults: Results from an international survey.
Barbarot S, Auziere S, Gadkari A, Girolomoni G, Puig L, Simpson EL, Margolis DJ, de Bruin-Weller M, Eckert L
Allergy 2018 Jun;73(6):1284-1293. Epub 2018 Feb 13 doi: 10.1111/all.13401. PMID: 29319189
Do long-chain omega-3 fatty acids protect from atopic dermatitis?
Reese I, Werfel T
J Dtsch Dermatol Ges 2015 Sep;13(9):879-85. doi: 10.1111/ddg.12780. PMID: 26882378

Recent systematic reviews

Global epidemiology of atopic dermatitis: a comprehensive systematic analysis and modelling study.
Tian J, Zhang D, Yang Y, Huang Y, Wang L, Yao X, Lu Q
Br J Dermatol 2023 Dec 20;190(1):55-61. doi: 10.1093/bjd/ljad339. PMID: 37705227
Systemic Immunomodulatory Treatments for Atopic Dermatitis: Update of a Living Systematic Review and Network Meta-analysis.
Drucker AM, Morra DE, Prieto-Merino D, Ellis AG, Yiu ZZN, Rochwerg B, Di Giorgio S, Arents BWM, Burton T, Spuls PI, Schmitt J, Flohr C
JAMA Dermatol 2022 May 1;158(5):523-532. doi: 10.1001/jamadermatol.2022.0455. PMID: 35293977Free PMC Article
Comparative efficacy and safety of systemic therapies used in moderate-to-severe atopic dermatitis: a systematic literature review and network meta-analysis.
Silverberg JI, Thyssen JP, Fahrbach K, Mickle K, Cappelleri JC, Romero W, Cameron MC, Myers DE, Clibborn C, DiBonaventura M
J Eur Acad Dermatol Venereol 2021 Sep;35(9):1797-1810. Epub 2021 Jun 12 doi: 10.1111/jdv.17351. PMID: 33991374Free PMC Article
Prevalence and Incidence of Atopic Dermatitis: A Systematic Review.
Bylund S, Kobyletzki LB, Svalstedt M, Svensson Å
Acta Derm Venereol 2020 Jun 9;100(12):adv00160. doi: 10.2340/00015555-3510. PMID: 32412646Free PMC Article
Oral Collagen Supplementation: A Systematic Review of Dermatological Applications.
Choi FD, Sung CT, Juhasz ML, Mesinkovsk NA
J Drugs Dermatol 2019 Jan 1;18(1):9-16. PMID: 30681787

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...