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Benign laryngeal neoplasm

MedGen UID:
56325
•Concept ID:
C0153952
•
Neoplastic Process
Synonyms: Benign Laryngeal Neoplasm; benign laryngeal neoplasm; Benign Laryngeal Tumor; benign laryngeal tumor; benign laryngeal tumour; Benign Larynx Neoplasm; benign larynx neoplasm; Benign Larynx Tumor; benign larynx tumor; benign larynx tumour; Benign neoplasm of larynx; Benign Neoplasm of Larynx; benign neoplasm of larynx; Benign Neoplasm of the Larynx; benign neoplasm of the larynx; Benign tumor of larynx; Benign Tumor of Larynx; benign tumor of larynx; Benign Tumor of the Larynx; benign tumor of the larynx; benign tumour of larynx; benign tumour of the larynx; laryngeal benign neoplasm; Laryngeal Neoplasm, Benign; laryngeal neoplasm, benign; larynx benign neoplasm
SNOMED CT: Benign tumor of larynx (92175003); Benign neoplasm of larynx (92175003)
 
Monarch Initiative: MONDO:0002354

Definition

A neoplasm that arises from the larynx and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Professional guidelines

PubMed

Diagnosis and Treatment of Laryngeal Schwannoma: A Systematic Review.
Tulli M, Bondi S, Smart CE, Giordano L, Trimarchi M, Galli A, Di Santo D, Biafora M, Bussi M
Otolaryngol Head Neck Surg 2018 Feb;158(2):222-231. Epub 2017 Oct 17 doi: 10.1177/0194599817735508. PMID: 29039258
Complications and Failures of Office-Based Endoscopic Angiolytic Laser Surgery Treatment.
Del Signore AG, Shah RN, Gupta N, Altman KW, Woo P
J Voice 2016 Nov;30(6):744-750. doi: 10.1016/j.jvoice.2015.08.022. PMID: 26433447
Otolaryngology clinic of North America: evidence-based practice: management of hoarseness/dysphonia.
Chang JI, Bevans SE, Schwartz SR
Otolaryngol Clin North Am 2012 Oct;45(5):1109-26. doi: 10.1016/j.otc.2012.06.012. PMID: 22980688

Recent clinical studies

Etiology

Mental Health and Dysphonia: Which Comes First, and Does That Change Care Utilization?
Jordan VA, Cohen S, Lunos S, Horvath KJ, Sieger G, Misono S
Laryngoscope 2020 May;130(5):1243-1248. Epub 2020 Feb 8 doi: 10.1002/lary.28203. PMID: 32034963Free PMC Article
Human papillomatosis genotyping and severity in patients with recurrent respiratory papillomatosis.
Intakorn P, Sonsuwan N
J Med Assoc Thai 2014 Jun;97 Suppl 6:S136-41. PMID: 25391185
Distribution and density of CD1a+ and CD83+ dendritic cells in HPV-associated laryngeal papillomas.
Kovalenko S, Lukashenko P, Romanovskaya A, Soldatski IL, Bakanov SI, Pfister H, Gerein V
Int J Pediatr Otorhinolaryngol 2009 Feb;73(2):249-56. Epub 2008 Dec 4 doi: 10.1016/j.ijporl.2008.10.016. PMID: 19062106
Aggressive recurrent respiratory papillomatosis in a neonate.
Loyo M, Pai SI, Netto GJ, Tunkel DE
Int J Pediatr Otorhinolaryngol 2008 Jun;72(6):917-20. Epub 2008 Apr 18 doi: 10.1016/j.ijporl.2008.02.022. PMID: 18423627

Diagnosis

Mental Health and Dysphonia: Which Comes First, and Does That Change Care Utilization?
Jordan VA, Cohen S, Lunos S, Horvath KJ, Sieger G, Misono S
Laryngoscope 2020 May;130(5):1243-1248. Epub 2020 Feb 8 doi: 10.1002/lary.28203. PMID: 32034963Free PMC Article
Human papillomatosis genotyping and severity in patients with recurrent respiratory papillomatosis.
Intakorn P, Sonsuwan N
J Med Assoc Thai 2014 Jun;97 Suppl 6:S136-41. PMID: 25391185
Aggressive recurrent respiratory papillomatosis in a neonate.
Loyo M, Pai SI, Netto GJ, Tunkel DE
Int J Pediatr Otorhinolaryngol 2008 Jun;72(6):917-20. Epub 2008 Apr 18 doi: 10.1016/j.ijporl.2008.02.022. PMID: 18423627
Laryngeal granular cell tumor.
Arevalo C, Maly B, Eliashar R, Gross M
J Voice 2008 May;22(3):339-42. Epub 2006 Nov 28 doi: 10.1016/j.jvoice.2006.10.003. PMID: 17134875

Therapy

Update on Recurrent Respiratory Papillomatosis.
Derkay CS, Bluher AE
Otolaryngol Clin North Am 2019 Aug;52(4):669-679. Epub 2019 May 8 doi: 10.1016/j.otc.2019.03.011. PMID: 31078306
Distribution and density of CD1a+ and CD83+ dendritic cells in HPV-associated laryngeal papillomas.
Kovalenko S, Lukashenko P, Romanovskaya A, Soldatski IL, Bakanov SI, Pfister H, Gerein V
Int J Pediatr Otorhinolaryngol 2009 Feb;73(2):249-56. Epub 2008 Dec 4 doi: 10.1016/j.ijporl.2008.10.016. PMID: 19062106
Aggressive recurrent respiratory papillomatosis in a neonate.
Loyo M, Pai SI, Netto GJ, Tunkel DE
Int J Pediatr Otorhinolaryngol 2008 Jun;72(6):917-20. Epub 2008 Apr 18 doi: 10.1016/j.ijporl.2008.02.022. PMID: 18423627

Prognosis

Human papillomatosis genotyping and severity in patients with recurrent respiratory papillomatosis.
Intakorn P, Sonsuwan N
J Med Assoc Thai 2014 Jun;97 Suppl 6:S136-41. PMID: 25391185
Distribution and density of CD1a+ and CD83+ dendritic cells in HPV-associated laryngeal papillomas.
Kovalenko S, Lukashenko P, Romanovskaya A, Soldatski IL, Bakanov SI, Pfister H, Gerein V
Int J Pediatr Otorhinolaryngol 2009 Feb;73(2):249-56. Epub 2008 Dec 4 doi: 10.1016/j.ijporl.2008.10.016. PMID: 19062106
Laryngeal granular cell tumor.
Arevalo C, Maly B, Eliashar R, Gross M
J Voice 2008 May;22(3):339-42. Epub 2006 Nov 28 doi: 10.1016/j.jvoice.2006.10.003. PMID: 17134875

Clinical prediction guides

Transcriptomic Landscape of Gene Expression Profiles and Pathways in Juvenile-Onset Recurrent Respiratory Papillomatosis Tumor Tissues and Human Papillomavirus 6 and 11 E6- and E7-Overexpressing Head and Neck Squamous Cell Carcinoma Cell Lines.
Wu X, Xiao Y, Zhou S, Wang Y, Wang J
J Virol 2022 Jan 26;96(2):e0134221. Epub 2021 Oct 20 doi: 10.1128/JVI.01342-21. PMID: 34669519Free PMC Article
Human papillomatosis genotyping and severity in patients with recurrent respiratory papillomatosis.
Intakorn P, Sonsuwan N
J Med Assoc Thai 2014 Jun;97 Suppl 6:S136-41. PMID: 25391185

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