U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Sebaceous gland carcinoma

MedGen UID:
64632
Concept ID:
C0206684
Neoplastic Process
Synonyms: Adenocarcinoma, Sebaceous; Adenocarcinomas, Sebaceous; Sebaceous Adenocarcinoma; Sebaceous Adenocarcinomas
SNOMED CT: Sebaceous adenocarcinoma (307599002); Sebaceous carcinoma (307599002); Carcinoma of sebaceous gland (307599002); Sebaceous adenocarcinoma (54734006); Sebaceous carcinoma (54734006)
 
HPO: HP:0030410
Monarch Initiative: MONDO:0006962

Definition

A carcinoma that arises in a sebaseous gland (an exocrine gland of the skin that secretes sebum, a waxy substance) [from HPO]

Conditions with this feature

Muir-Torré syndrome
MedGen UID:
231157
Concept ID:
C1321489
Neoplastic Process
Lynch syndrome is characterized by an increased risk for colorectal cancer (CRC) and cancers of the endometrium, ovary, stomach, small bowel, urinary tract, biliary tract, brain (usually glioblastoma), skin (sebaceous adenomas, sebaceous carcinomas, and keratoacanthomas), pancreas, and prostate. Cancer risks and age of onset vary depending on the associated gene. Several other cancer types have been reported to occur in individuals with Lynch syndrome (e.g., breast, sarcomas, adrenocortical carcinoma). However, the data are not sufficient to demonstrate that the risk of developing these cancers is increased in individuals with Lynch syndrome.

Professional guidelines

PubMed

Alam MS, Pal SS, Krishnakumar S
Indian J Ophthalmol 2022 Jun;70(6):1975-1981. doi: 10.4103/ijo.IJO_2724_21. PMID: 35647965Free PMC Article
McGrath LA, Currie ZI, Mudhar HS, Tan JHY, Salvi SM
Eye (Lond) 2020 Sep;34(9):1685-1692. Epub 2020 Jan 2 doi: 10.1038/s41433-019-0756-9. PMID: 31896805Free PMC Article
Cook BE Jr, Bartley GB
Ophthalmology 2001 Nov;108(11):2088-98; quiz 2099-100, 2121. doi: 10.1016/s0161-6420(01)00796-5. PMID: 11713084

Recent clinical studies

Etiology

Nie Z, Geng J, Xu X, Zhang R, Li D
Cancer Med 2023 Jul;12(14):14912-14921. Epub 2023 Jun 30 doi: 10.1002/cam4.6126. PMID: 37387455Free PMC Article
Alam MS, Pal SS, Krishnakumar S
Indian J Ophthalmol 2022 Jun;70(6):1975-1981. doi: 10.4103/ijo.IJO_2724_21. PMID: 35647965Free PMC Article
Kaliki S, Morawala A, Krishnamurthy A, Divya Jajapuram S, Mohamed A
Ophthalmic Plast Reconstr Surg 2021 Jul-Aug 01;37(4):341-345. doi: 10.1097/IOP.0000000000001863. PMID: 33237664
McGrath LA, Currie ZI, Mudhar HS, Tan JHY, Salvi SM
Eye (Lond) 2020 Sep;34(9):1685-1692. Epub 2020 Jan 2 doi: 10.1038/s41433-019-0756-9. PMID: 31896805Free PMC Article
Pe'er J
Indian J Ophthalmol 2016 Mar;64(3):177-90. doi: 10.4103/0301-4738.181752. PMID: 27146927Free PMC Article

Diagnosis

Yunoki T, Hirano T, Tabuchi Y, Furusawa Y, Torigoe M, Nakajima T, Imura J, Hayashi A
Int Ophthalmol 2020 Feb;40(2):343-350. Epub 2019 Sep 30 doi: 10.1007/s10792-019-01185-7. PMID: 31571090
Cicinelli MV, Kaliki S
Int Ophthalmol 2019 May;39(5):1187-1197. Epub 2018 Apr 25 doi: 10.1007/s10792-018-0925-z. PMID: 29696467
Honavar SG
Indian J Ophthalmol 2018 Sep;66(9):1235-1237. doi: 10.4103/ijo.IJO_1370_18. PMID: 30127131Free PMC Article
Aronow ME, Singh AD
Dev Ophthalmol 2013;52:85-93. Epub 2013 Aug 26 doi: 10.1159/000351062. PMID: 23989129
Lober CW, Fenske NA
J Am Acad Dermatol 1991 Oct;25(4):685-90. doi: 10.1016/0190-9622(91)70254-y. PMID: 1791226

Therapy

Alam MS, Banerjee P, Krishnakumar S
Indian J Ophthalmol 2022 Feb;70(2):630-633. doi: 10.4103/ijo.IJO_1814_21. PMID: 35086251Free PMC Article
Garcia A, Nelson K, Patel V
Cancer Treat Rev 2021 Nov;100:102266. Epub 2021 Aug 16 doi: 10.1016/j.ctrv.2021.102266. PMID: 34418780
Kaliki S, Ayyar A, Nair AG, Mishra DK, Reddy VA, Naik MN
Ophthalmic Plast Reconstr Surg 2016 Jan-Feb;32(1):35-9. doi: 10.1097/IOP.0000000000000398. PMID: 25675161
Shields CL, Naseripour M, Shields JA, Eagle RC Jr
Ophthalmology 2002 Nov;109(11):2129-33. doi: 10.1016/s0161-6420(02)01239-3. PMID: 12414427
Zouboulis CC, Boschnakow A
Clin Exp Dermatol 2001 Oct;26(7):600-7. doi: 10.1046/j.1365-2230.2001.00894.x. PMID: 11696064

Prognosis

Nie Z, Geng J, Xu X, Zhang R, Li D
Cancer Med 2023 Jul;12(14):14912-14921. Epub 2023 Jun 30 doi: 10.1002/cam4.6126. PMID: 37387455Free PMC Article
Kaliki S, Morawala A, Dharap RS, Mohamed A
Eye (Lond) 2021 Oct;35(10):2864-2870. Epub 2020 Dec 15 doi: 10.1038/s41433-020-01340-w. PMID: 33323987Free PMC Article
Hirano T, Yunoki T, Furusawa Y, Tabuchi Y, Hayashi A
Mol Med Rep 2021 Jan;23(1) Epub 2020 Nov 12 doi: 10.3892/mmr.2020.11682. PMID: 33179085Free PMC Article
AlHammad F, Edward DP, Alkatan HM, Elkhamary S, Iuliano A, Maktabi A, Al-Horani SE, Al-Sheikh O, Al Hussain H, Strianese D
Eur J Ophthalmol 2021 Jul;31(4):2055-2063. Epub 2020 Jun 21 doi: 10.1177/1120672120936488. PMID: 32567368
Cicinelli MV, Kaliki S
Int Ophthalmol 2019 May;39(5):1187-1197. Epub 2018 Apr 25 doi: 10.1007/s10792-018-0925-z. PMID: 29696467

Clinical prediction guides

Nie Z, Geng J, Xu X, Zhang R, Li D
Cancer Med 2023 Jul;12(14):14912-14921. Epub 2023 Jun 30 doi: 10.1002/cam4.6126. PMID: 37387455Free PMC Article
Mangan MS, Ozcan Z, Ozkan Aksoy N
Rom J Ophthalmol 2021 Jul-Sep;65(3):290-292. doi: 10.22336/rjo.2021.59. PMID: 35036655Free PMC Article
Kaliki S, Morawala A, Dharap RS, Mohamed A
Eye (Lond) 2021 Oct;35(10):2864-2870. Epub 2020 Dec 15 doi: 10.1038/s41433-020-01340-w. PMID: 33323987Free PMC Article
AlHammad F, Edward DP, Alkatan HM, Elkhamary S, Iuliano A, Maktabi A, Al-Horani SE, Al-Sheikh O, Al Hussain H, Strianese D
Eur J Ophthalmol 2021 Jul;31(4):2055-2063. Epub 2020 Jun 21 doi: 10.1177/1120672120936488. PMID: 32567368
Bhardwaj M, Sen S, Chosdol K, Bakhshi S, Pushker N, Sharma A, Kashyap S, Bajaj MS, Singh VK
Br J Ophthalmol 2020 Jun;104(6):879-884. Epub 2019 Apr 2 doi: 10.1136/bjophthalmol-2018-313285. PMID: 30940620

Recent systematic reviews

Garcia A, Nelson K, Patel V
Cancer Treat Rev 2021 Nov;100:102266. Epub 2021 Aug 16 doi: 10.1016/j.ctrv.2021.102266. PMID: 34418780

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...