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Anterior urethra cancer

MedGen UID:
76043
•Concept ID:
C0279930
•
Neoplastic Process
Synonyms: anterior urethra cancer; Anterior Urethra Malignant Neoplasm; anterior urethra malignant neoplasm; Anterior Urethra Malignant Tumor; anterior urethra malignant tumor; anterior urethra malignant tumour; anterior urethral cancer; Anterior Urethral Malignant Neoplasm; anterior urethral malignant neoplasm; Anterior Urethral Malignant Tumor; anterior urethral malignant tumor; anterior urethral malignant tumour; Malignant Neoplasm of Anterior Urethra; malignant neoplasm of anterior urethra; Malignant Neoplasm of the Anterior Urethra; malignant neoplasm of the anterior urethra; Malignant Tumor of Anterior Urethra; malignant tumor of anterior urethra; Malignant Tumor of the Anterior Urethra; malignant tumor of the anterior urethra; malignant tumour of anterior urethra; malignant tumour of the anterior urethra
 
Monarch Initiative: MONDO:0004518

Definition

A primary or metastatic malignant neoplasm involving the anterior portion of the urethra. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnterior urethra cancer

Professional guidelines

PubMed

Which technology to select for primary focal treatment of prostate cancer?-European Section of Urotechnology (ESUT) position statement.
Ganzer R, Arthanareeswaran VKA, Ahmed HU, Cestari A, Rischmann P, Salomon G, Teber D, Liatsikos E, Stolzenburg JU, Barret E
Prostate Cancer Prostatic Dis 2018 Jun;21(2):175-186. Epub 2018 May 9 doi: 10.1038/s41391-018-0042-0. PMID: 29743538
Targeted Anterior Gland Focal Therapy-a Novel Treatment Option for a Better Defined Disease.
Tay KJ, Villers A, Polascik TJ
Curr Urol Rep 2016 Oct;17(10):69. doi: 10.1007/s11934-016-0628-9. PMID: 27502428
EAU guidelines on primary urethral carcinoma.
Gakis G, Witjes JA, Compérat E, Cowan NC, De Santis M, Lebret T, Ribal MJ, Sherif AM; European Association of Urology
Eur Urol 2013 Nov;64(5):823-30. Epub 2013 Apr 2 doi: 10.1016/j.eururo.2013.03.044. PMID: 23582479

Recent clinical studies

Etiology

Robotic Female Radical Cystectomy.
Truong H, Maxon V, Goh AC
J Endourol 2021 Sep;35(S2):S106-S115. doi: 10.1089/end.2020.1190. PMID: 34499552Free PMC Article
Hood Technique for Robotic Radical Prostatectomy-Preserving Periurethral Anatomical Structures in the Space of Retzius and Sparing the Pouch of Douglas, Enabling Early Return of Continence Without Compromising Surgical Margin Rates.
Wagaskar VG, Mittal A, Sobotka S, Ratnani P, Lantz A, Falagario UG, Martini A, Dovey Z, Treacy PJ, Pathak P, Nair S, Roy B, Chakravarty D, Lewis S, Haines K 3rd, Wiklund P, Tewari A
Eur Urol 2021 Aug;80(2):213-221. Epub 2020 Oct 14 doi: 10.1016/j.eururo.2020.09.044. PMID: 33067016
Female Urethra Adenocarcinoma.
Dell'Atti L, Galosi AB
Clin Genitourin Cancer 2018 Apr;16(2):e263-e267. Epub 2017 Oct 16 doi: 10.1016/j.clgc.2017.10.006. PMID: 29113768
EAU guidelines on primary urethral carcinoma.
Gakis G, Witjes JA, Compérat E, Cowan NC, De Santis M, Lebret T, Ribal MJ, Sherif AM; European Association of Urology
Eur Urol 2013 Nov;64(5):823-30. Epub 2013 Apr 2 doi: 10.1016/j.eururo.2013.03.044. PMID: 23582479
Indications for urethrectomy.
Elmajian DA
Semin Urol Oncol 2001 Feb;19(1):37-44. PMID: 11246732

Diagnosis

Female Urethra Adenocarcinoma.
Dell'Atti L, Galosi AB
Clin Genitourin Cancer 2018 Apr;16(2):e263-e267. Epub 2017 Oct 16 doi: 10.1016/j.clgc.2017.10.006. PMID: 29113768
Multiparametric MRI of the anterior prostate gland: clinical-radiological-histopathological correlation.
Moosavi B, Flood TA, Al-Dandan O, Breau RH, Cagiannos I, Morash C, Malone SC, Schieda N
Clin Radiol 2016 May;71(5):405-17. Epub 2016 Feb 14 doi: 10.1016/j.crad.2016.01.002. PMID: 26888762
Clear cell adenocarcinoma of the urethra: review of the literature.
Venyo AK
Int J Surg Oncol 2015;2015:790235. Epub 2015 Jan 20 doi: 10.1155/2015/790235. PMID: 25685552Free PMC Article
Paraurethral leiomyoma.
Perugia G, Ciccariello M, Pirolli F, Chinazzi A, Teodonio S, Borgoni G, Croce F, Liberti M
Urology 2012 Apr;79(4):e51-2. Epub 2011 Oct 19 doi: 10.1016/j.urology.2011.08.004. PMID: 22014968
Imaging of male urethra.
Pavlica P, Barozzi L, Menchi I
Eur Radiol 2003 Jul;13(7):1583-96. Epub 2002 Dec 19 doi: 10.1007/s00330-002-1758-7. PMID: 12835971

Therapy

Hood Technique for Robotic Radical Prostatectomy-Preserving Periurethral Anatomical Structures in the Space of Retzius and Sparing the Pouch of Douglas, Enabling Early Return of Continence Without Compromising Surgical Margin Rates.
Wagaskar VG, Mittal A, Sobotka S, Ratnani P, Lantz A, Falagario UG, Martini A, Dovey Z, Treacy PJ, Pathak P, Nair S, Roy B, Chakravarty D, Lewis S, Haines K 3rd, Wiklund P, Tewari A
Eur Urol 2021 Aug;80(2):213-221. Epub 2020 Oct 14 doi: 10.1016/j.eururo.2020.09.044. PMID: 33067016
Technical details to achieve perfect early continence after radical prostatectomy.
Manfredi M, Fiori C, Amparore D, Checcucci E, Porpiglia F
Minerva Chir 2019 Feb;74(1):63-77. Epub 2018 Jul 23 doi: 10.23736/S0026-4733.18.07761-1. PMID: 30037176
Pathophysiology and Contributing Factors in Postprostatectomy Incontinence: A Review.
Heesakkers J, Farag F, Bauer RM, Sandhu J, De Ridder D, Stenzl A
Eur Urol 2017 Jun;71(6):936-944. Epub 2016 Oct 6 doi: 10.1016/j.eururo.2016.09.031. PMID: 27720536
What's new in urethroplasty?
Andrich DE, Mundy AR
Curr Opin Urol 2011 Nov;21(6):455-60. doi: 10.1097/MOU.0b013e32834b154d. PMID: 21897261
Balanitis xerotica obliterans--a review.
Das S, Tunuguntla HS
World J Urol 2000 Dec;18(6):382-7. doi: 10.1007/PL00007083. PMID: 11204255

Prognosis

Female Urethra Adenocarcinoma.
Dell'Atti L, Galosi AB
Clin Genitourin Cancer 2018 Apr;16(2):e263-e267. Epub 2017 Oct 16 doi: 10.1016/j.clgc.2017.10.006. PMID: 29113768
Clear cell adenocarcinoma of the urethra: review of the literature.
Venyo AK
Int J Surg Oncol 2015;2015:790235. Epub 2015 Jan 20 doi: 10.1155/2015/790235. PMID: 25685552Free PMC Article
EAU guidelines on primary urethral carcinoma.
Gakis G, Witjes JA, Compérat E, Cowan NC, De Santis M, Lebret T, Ribal MJ, Sherif AM; European Association of Urology
Eur Urol 2013 Nov;64(5):823-30. Epub 2013 Apr 2 doi: 10.1016/j.eururo.2013.03.044. PMID: 23582479
Melanoma of the female urethra.
Papeš D, Altarac S
Med Oncol 2013 Mar;30(1):329. Epub 2012 Dec 18 doi: 10.1007/s12032-012-0329-2. PMID: 23254965
MR imaging of the male and female urethra.
Ryu J, Kim B
Radiographics 2001 Sep-Oct;21(5):1169-85. doi: 10.1148/radiographics.21.5.g01se121169. PMID: 11553824

Clinical prediction guides

Morphological and clinical evaluation of prostatic urethra using modified sonourethrography with retrograde jelly injection.
Minagawa T, Daimon H, Ogawa N, Saito T, Suzuki T, Domen T, Nagai T, Ogawa T, Ishizuka O
Low Urin Tract Symptoms 2019 Apr;11(2):O4-O10. Epub 2017 Nov 29 doi: 10.1111/luts.12203. PMID: 29193884
Partial Prostatectomy for Anterior Cancer: Short-term Oncologic and Functional Outcomes.
Villers A, Puech P, Flamand V, Haber GP, Desai MM, Crouzet S, Leroy X, Chopra S, Lemaitre L, Ouzzane A, Gill IS
Eur Urol 2017 Sep;72(3):333-342. Epub 2016 Sep 6 doi: 10.1016/j.eururo.2016.08.057. PMID: 27613061Free PMC Article
Urethra-sparing high-intensity focused ultrasound for localized prostate cancer: Functional and oncological outcomes.
Shoji S, Nakano M, Fujikawa H, Endo K, Hashimoto A, Tomonaga T, Terachi T, Uchida T
Int J Urol 2015 Nov;22(11):1043-9. Epub 2015 Aug 6 doi: 10.1111/iju.12876. PMID: 26251127
EAU guidelines on primary urethral carcinoma.
Gakis G, Witjes JA, Compérat E, Cowan NC, De Santis M, Lebret T, Ribal MJ, Sherif AM; European Association of Urology
Eur Urol 2013 Nov;64(5):823-30. Epub 2013 Apr 2 doi: 10.1016/j.eururo.2013.03.044. PMID: 23582479
MR imaging of the male and female urethra.
Ryu J, Kim B
Radiographics 2001 Sep-Oct;21(5):1169-85. doi: 10.1148/radiographics.21.5.g01se121169. PMID: 11553824

Recent systematic reviews

Efficacy of Mitomycin C Combined with Direct Vision Internal Urethrotomy for Urethral Strictures: A Systematic Review and Meta-Analysis.
Xu C, Zhu Z, Lin L, Lv T, Cai T, Lin J
Urol Int 2023;107(4):344-357. Epub 2021 Oct 20 doi: 10.1159/000518977. PMID: 34670219
Vaginal Complications after Radical Cystectomy for Bladder Cancer: A Systematic Review.
Richter LA, Egan J, Alagha EC, Handa VL
Urology 2021 Oct;156:e20-e29. Epub 2021 Jul 17 doi: 10.1016/j.urology.2021.07.001. PMID: 34284007Free PMC Article

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