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Larynx verrucous carcinoma

MedGen UID:
76097
Concept ID:
C0280328
Neoplastic Process
Synonyms: laryngeal throat verrucous cancer; Laryngeal Verrucous Carcinoma; laryngeal verrucous carcinoma; Larynx Verrucous Carcinoma; larynx verrucous carcinoma; Verrucous Carcinoma of Larynx; verrucous carcinoma of larynx; Verrucous Carcinoma of the Larynx; verrucous carcinoma of the larynx
 
Monarch Initiative: MONDO:0002766

Definition

A well differentaited, non-metastasizing squamous cell carcinoma arising from the larynx. It is an exophytic, warty, and slow growing tumor affecting predominantly older men. It is associated with tobacco smoking. Symptoms include hoarseness, airway obstruction, weight loss, dysphagia, and throat pain. If left untreated, it may cause extensive local destruction. [from NCI]

Professional guidelines

PubMed

López F, Williams MD, Cardesa A, Hunt JL, Strojan P, Rinaldo A, Nixon IJ, Rodrigo JP, Saba NF, Mendenhall WM, Quer M, Suárez C, Ferlito A
Eur Arch Otorhinolaryngol 2017 Jul;274(7):2709-2726. Epub 2017 Mar 31 doi: 10.1007/s00405-017-4533-8. PMID: 28364287
Hristov B, Bajaj GK
Otolaryngol Clin North Am 2008 Aug;41(4):715-40, vi. doi: 10.1016/j.otc.2008.01.017. PMID: 18570955
Ferlito A
Ann Otol Rhinol Laryngol 1985 Nov-Dec;94(6 Pt 1):575-9. doi: 10.1177/000348948509400610. PMID: 3907472

Recent clinical studies

Diagnosis

Tan E, Mody MD, Saba NF
Oral Oncol 2018 Jul;82:61-68. Epub 2018 May 26 doi: 10.1016/j.oraloncology.2018.05.005. PMID: 29909903

Therapy

Tan E, Mody MD, Saba NF
Oral Oncol 2018 Jul;82:61-68. Epub 2018 May 26 doi: 10.1016/j.oraloncology.2018.05.005. PMID: 29909903

Prognosis

Echanique KA, Desai SV, Marchiano E, Spinazzi EF, Strojan P, Baredes S, Eloy JA
Otolaryngol Head Neck Surg 2017 Jan;156(1):38-45. Epub 2016 Aug 9 doi: 10.1177/0194599816662631. PMID: 27484231

Recent systematic reviews

Echanique KA, Desai SV, Marchiano E, Spinazzi EF, Strojan P, Baredes S, Eloy JA
Otolaryngol Head Neck Surg 2017 Jan;156(1):38-45. Epub 2016 Aug 9 doi: 10.1177/0194599816662631. PMID: 27484231

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