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Larynx cancer

MedGen UID:
2868
Concept ID:
C0007107
Neoplastic Process
Synonym: Laryngeal cancer
SNOMED CT: CA - Cancer of larynx (363429002); Laryngeal cancer (363429002); Cancer of larynx (363429002); Malignant tumor of larynx (363429002)
 
Monarch Initiative: MONDO:0002352

Definition

A primary or metastatic malignant neoplasm involving the larynx. The majority are carcinomas. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLarynx cancer

Professional guidelines

PubMed

Biau J, Pointreau Y, Blanchard P, Khampan C, Giraud P, Lapeyre M, Maingon P
Cancer Radiother 2022 Feb-Apr;26(1-2):206-212. Epub 2021 Dec 22 doi: 10.1016/j.canrad.2021.09.004. PMID: 34953705
Han J, Sumer BD
Ann Surg Oncol 2021 Nov;28(12):6927-6928. Epub 2021 Aug 24 doi: 10.1245/s10434-021-10657-z. PMID: 34431018
Kennedy WR, Amdur RJ, Boyce BJ, Dziegielewski P, Morris CG, Mendenhall WM
Oncol Res Treat 2017;40(9):503-506. Epub 2017 Aug 21 doi: 10.1159/000477463. PMID: 28848123

Curated

NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Head and Neck Cancers, 2024

Recent clinical studies

Etiology

Liberale C, Soloperto D, Marchioni A, Monzani D, Sacchetto L
Int J Mol Sci 2023 Aug 18;24(16) doi: 10.3390/ijms241612913. PMID: 37629093Free PMC Article
Hayes RB, Ahn J, Fan X, Peters BA, Ma Y, Yang L, Agalliu I, Burk RD, Ganly I, Purdue MP, Freedman ND, Gapstur SM, Pei Z
JAMA Oncol 2018 Mar 1;4(3):358-365. doi: 10.1001/jamaoncol.2017.4777. PMID: 29327043Free PMC Article
Steuer CE, El-Deiry M, Parks JR, Higgins KA, Saba NF
CA Cancer J Clin 2017 Jan;67(1):31-50. Epub 2016 Nov 29 doi: 10.3322/caac.21386. PMID: 27898173
Bayer O, Cámara R, Zeissig SR, Ressing M, Dietz A, Locati LD, Ramroth H, Singer S
Eur Arch Otorhinolaryngol 2016 Jan;273(1):9-20. Epub 2014 Oct 14 doi: 10.1007/s00405-014-3321-y. PMID: 25311307
Forastiere AA, Zhang Q, Weber RS, Maor MH, Goepfert H, Pajak TF, Morrison W, Glisson B, Trotti A, Ridge JA, Thorstad W, Wagner H, Ensley JF, Cooper JS
J Clin Oncol 2013 Mar 1;31(7):845-52. Epub 2012 Nov 26 doi: 10.1200/JCO.2012.43.6097. PMID: 23182993Free PMC Article

Diagnosis

Sun L, Brody R, Candelieri D, Lynch JA, Cohen RB, Li Y, Getz KD, Ky B
JAMA Otolaryngol Head Neck Surg 2023 Aug 1;149(8):717-725. doi: 10.1001/jamaoto.2023.1342. PMID: 37347472Free PMC Article
Cavaliere M, Bisogno A, Scarpa A, D'Urso A, Marra P, Colacurcio V, De Luca P, Ralli M, Cassandro E, Cassandro C
Ann Diagn Pathol 2021 Oct;54:151787. Epub 2021 Jul 2 doi: 10.1016/j.anndiagpath.2021.151787. PMID: 34242969
Cypko MA, Stoehr M
Minim Invasive Ther Allied Technol 2019 Apr;28(2):105-119. Epub 2019 Feb 27 doi: 10.1080/13645706.2019.1584572. PMID: 30810428
Steuer CE, El-Deiry M, Parks JR, Higgins KA, Saba NF
CA Cancer J Clin 2017 Jan;67(1):31-50. Epub 2016 Nov 29 doi: 10.3322/caac.21386. PMID: 27898173
Marchiano E, Chin OY, Fang CH, Park RC, Baredes S, Eloy JA
Otolaryngol Head Neck Surg 2016 Mar;154(3):433-9. Epub 2015 Dec 23 doi: 10.1177/0194599815621884. PMID: 26701176

Therapy

Liberale C, Soloperto D, Marchioni A, Monzani D, Sacchetto L
Int J Mol Sci 2023 Aug 18;24(16) doi: 10.3390/ijms241612913. PMID: 37629093Free PMC Article
Saraswathula A, Austin JM, Fakhry C, Vosler PS, Mandal R, Koch WM, Tan M, Eisele DW, Frick KD, Gourin CG
Laryngoscope 2023 Apr;133(4):834-840. Epub 2022 May 30 doi: 10.1002/lary.30229. PMID: 35634691Free PMC Article
Hayes RB, Ahn J, Fan X, Peters BA, Ma Y, Yang L, Agalliu I, Burk RD, Ganly I, Purdue MP, Freedman ND, Gapstur SM, Pei Z
JAMA Oncol 2018 Mar 1;4(3):358-365. doi: 10.1001/jamaoncol.2017.4777. PMID: 29327043Free PMC Article
Bayer O, Cámara R, Zeissig SR, Ressing M, Dietz A, Locati LD, Ramroth H, Singer S
Eur Arch Otorhinolaryngol 2016 Jan;273(1):9-20. Epub 2014 Oct 14 doi: 10.1007/s00405-014-3321-y. PMID: 25311307
Forastiere AA, Zhang Q, Weber RS, Maor MH, Goepfert H, Pajak TF, Morrison W, Glisson B, Trotti A, Ridge JA, Thorstad W, Wagner H, Ensley JF, Cooper JS
J Clin Oncol 2013 Mar 1;31(7):845-52. Epub 2012 Nov 26 doi: 10.1200/JCO.2012.43.6097. PMID: 23182993Free PMC Article

Prognosis

Arenaz Búa B, Pendleton H, Westin U, Rydell R
Acta Otolaryngol 2018 Feb;138(2):170-174. Epub 2017 Oct 5 doi: 10.1080/00016489.2017.1384056. PMID: 28978261
Steuer CE, El-Deiry M, Parks JR, Higgins KA, Saba NF
CA Cancer J Clin 2017 Jan;67(1):31-50. Epub 2016 Nov 29 doi: 10.3322/caac.21386. PMID: 27898173
Echanique KA, Desai SV, Marchiano E, Spinazzi EF, Strojan P, Baredes S, Eloy JA
Otolaryngol Head Neck Surg 2017 Jan;156(1):38-45. Epub 2016 Aug 9 doi: 10.1177/0194599816662631. PMID: 27484231
Forastiere AA, Zhang Q, Weber RS, Maor MH, Goepfert H, Pajak TF, Morrison W, Glisson B, Trotti A, Ridge JA, Thorstad W, Wagner H, Ensley JF, Cooper JS
J Clin Oncol 2013 Mar 1;31(7):845-52. Epub 2012 Nov 26 doi: 10.1200/JCO.2012.43.6097. PMID: 23182993Free PMC Article
Strome SE, Weinman EC
Curr Treat Options Oncol 2002 Feb;3(1):11-20. doi: 10.1007/s11864-002-0037-9. PMID: 12057083

Clinical prediction guides

Prasad A, Carey RM, Panara K, Rajasekaran K, Cannady SB, Newman JG, Brant JA, Brody RM
Head Neck 2023 Sep;45(9):2303-2312. Epub 2023 Jul 5 doi: 10.1002/hed.27437. PMID: 37403903
Saraswathula A, Austin JM, Fakhry C, Vosler PS, Mandal R, Koch WM, Tan M, Eisele DW, Frick KD, Gourin CG
Laryngoscope 2023 Apr;133(4):834-840. Epub 2022 May 30 doi: 10.1002/lary.30229. PMID: 35634691Free PMC Article
Hayes RB, Ahn J, Fan X, Peters BA, Ma Y, Yang L, Agalliu I, Burk RD, Ganly I, Purdue MP, Freedman ND, Gapstur SM, Pei Z
JAMA Oncol 2018 Mar 1;4(3):358-365. doi: 10.1001/jamaoncol.2017.4777. PMID: 29327043Free PMC Article
Steuer CE, El-Deiry M, Parks JR, Higgins KA, Saba NF
CA Cancer J Clin 2017 Jan;67(1):31-50. Epub 2016 Nov 29 doi: 10.3322/caac.21386. PMID: 27898173
Bayer O, Cámara R, Zeissig SR, Ressing M, Dietz A, Locati LD, Ramroth H, Singer S
Eur Arch Otorhinolaryngol 2016 Jan;273(1):9-20. Epub 2014 Oct 14 doi: 10.1007/s00405-014-3321-y. PMID: 25311307

Recent systematic reviews

GBD 2019 Respiratory Tract Cancers Collaborators
Lancet Respir Med 2021 Sep;9(9):1030-1049. Epub 2021 Aug 16 doi: 10.1016/S2213-2600(21)00164-8. PMID: 34411511Free PMC Article
Echanique KA, Desai SV, Marchiano E, Spinazzi EF, Strojan P, Baredes S, Eloy JA
Otolaryngol Head Neck Surg 2017 Jan;156(1):38-45. Epub 2016 Aug 9 doi: 10.1177/0194599816662631. PMID: 27484231
Chin OY, Dubal PM, Sheikh AB, Unsal AA, Park RC, Baredes S, Eloy JA
Laryngoscope 2017 Feb;127(2):430-439. Epub 2016 Jun 12 doi: 10.1002/lary.26068. PMID: 27291822
Marchiano E, Chin OY, Fang CH, Park RC, Baredes S, Eloy JA
Otolaryngol Head Neck Surg 2016 Mar;154(3):433-9. Epub 2015 Dec 23 doi: 10.1177/0194599815621884. PMID: 26701176
Bayer O, Cámara R, Zeissig SR, Ressing M, Dietz A, Locati LD, Ramroth H, Singer S
Eur Arch Otorhinolaryngol 2016 Jan;273(1):9-20. Epub 2014 Oct 14 doi: 10.1007/s00405-014-3321-y. PMID: 25311307

Supplemental Content

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    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NCCN, 2024
      NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Head and Neck Cancers, 2024

    Consumer resources

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