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Submandibular Gland Carcinoma

MedGen UID:
83384
Concept ID:
C0345607
Neoplastic Process
Synonyms: Carcinoma of submandibular gland; Carcinoma of Submandibular Gland; Carcinoma of the Submandibular Gland
SNOMED CT: Carcinoma of submandibular gland (254465004)

Definition

A carcinoma that arises from the submandibular gland. Representative examples include mucoepidermoid carcinoma, adenoid cystic carcinoma, and carcinoma ex pleomorphic adenoma. [from NCI]

Professional guidelines

PubMed

Liu S, Xu W, Liu L, Zhu Y, Wu Y, Lu H, Yang W, Zhang C
Oral Dis 2023 Nov;29(8):3298-3305. Epub 2022 Jul 19 doi: 10.1111/odi.14313. PMID: 35821655
Kaszuba SM, Zafereo ME, Rosenthal DI, El-Naggar AK, Weber RS
Arch Otolaryngol Head Neck Surg 2007 Jun;133(6):546-50. doi: 10.1001/archotol.133.6.546. PMID: 17576904

Recent clinical studies

Etiology

Sajisevi M, Nguyen K, Callas P, Holcomb AJ, Vural E, Davis KP, Thomas CM, Plonowska-Hirschfeld KA, Stein JS, Eskander A, Kakarala K, Enepekides DJ, Hier MP, Ryan WR; American Head and Neck Society Salivary Gland Section, Asarkar AA, Aulet R, Bell RK, Blasco MA, Bowmaster VB, Burruss CP, Chung J, Chan K, Chang BA, Coffey CS, Cognetti DM, Cooper DJ, Cordero J, Donovan J, Du YJ, Dundar Y, Dedivitis RA, Edwards HA, Erovic BM, Feinberg PA, Garvey EA, Goldstein DP, Goodman JF, Goulart RN, Goyal N, Grasl S, Giurintano JP, Gupta N, Habib AM, Hackman TG, Hara JH, Henson C, Hinni ML, Hua N, Johnson-Obaseki S, Juloori A, Kalman NS, Kejner AE, Khaja SF, Ku JA, Lambert A, Luu BK, Magliocca KR, Dos Santos LRM, Michael C, Miles BA, de Melo GM, Moore MG, Morand GB, Moura K, Mukdad L, Noroozi H, Patel R, Paydarfar JA, Sadeghi N, Savaria FN, Schmitt NC, Shapiro J, Shaver TB, Stoeckli SJ, St John M, Stokes WA, Sulibhavi A, Tasoulas J, Vendra V, Vinh DB, Virgen CG, Wooten C, Woody NM, Young GD
JAMA Otolaryngol Head Neck Surg 2024 Feb 1;150(2):107-116. doi: 10.1001/jamaoto.2023.3952. PMID: 38095911Free PMC Article
Westergaard-Nielsen M, Godballe C, Eriksen JG, Larsen SR, Kiss K, Agander T, Ulhøi BP, Charabi BW, Klug TE, Jacobsen H, Johansen J, Kristensen CA, Andersen E, Andersen M, Bjørndal K
Eur Arch Otorhinolaryngol 2023 Jul;280(7):3405-3413. Epub 2023 Apr 13 doi: 10.1007/s00405-023-07940-y. PMID: 37052687Free PMC Article
Liu S, Xu W, Liu L, Zhu Y, Wu Y, Lu H, Yang W, Zhang C
Oral Dis 2023 Nov;29(8):3298-3305. Epub 2022 Jul 19 doi: 10.1111/odi.14313. PMID: 35821655
Hsieh CE, Lee LY, Chou YC, Fan KH, Tsang NM, Chang JT, Wang HM, Ng SH, Liao CT, Yen TC, Fang KH, Lin CY
Radiat Oncol 2018 Sep 21;13(1):184. doi: 10.1186/s13014-018-1130-y. PMID: 30241545Free PMC Article
Kaszuba SM, Zafereo ME, Rosenthal DI, El-Naggar AK, Weber RS
Arch Otolaryngol Head Neck Surg 2007 Jun;133(6):546-50. doi: 10.1001/archotol.133.6.546. PMID: 17576904

Diagnosis

Sajisevi M, Nguyen K, Callas P, Holcomb AJ, Vural E, Davis KP, Thomas CM, Plonowska-Hirschfeld KA, Stein JS, Eskander A, Kakarala K, Enepekides DJ, Hier MP, Ryan WR; American Head and Neck Society Salivary Gland Section, Asarkar AA, Aulet R, Bell RK, Blasco MA, Bowmaster VB, Burruss CP, Chung J, Chan K, Chang BA, Coffey CS, Cognetti DM, Cooper DJ, Cordero J, Donovan J, Du YJ, Dundar Y, Dedivitis RA, Edwards HA, Erovic BM, Feinberg PA, Garvey EA, Goldstein DP, Goodman JF, Goulart RN, Goyal N, Grasl S, Giurintano JP, Gupta N, Habib AM, Hackman TG, Hara JH, Henson C, Hinni ML, Hua N, Johnson-Obaseki S, Juloori A, Kalman NS, Kejner AE, Khaja SF, Ku JA, Lambert A, Luu BK, Magliocca KR, Dos Santos LRM, Michael C, Miles BA, de Melo GM, Moore MG, Morand GB, Moura K, Mukdad L, Noroozi H, Patel R, Paydarfar JA, Sadeghi N, Savaria FN, Schmitt NC, Shapiro J, Shaver TB, Stoeckli SJ, St John M, Stokes WA, Sulibhavi A, Tasoulas J, Vendra V, Vinh DB, Virgen CG, Wooten C, Woody NM, Young GD
JAMA Otolaryngol Head Neck Surg 2024 Feb 1;150(2):107-116. doi: 10.1001/jamaoto.2023.3952. PMID: 38095911Free PMC Article
Westergaard-Nielsen M, Godballe C, Eriksen JG, Larsen SR, Kiss K, Agander T, Ulhøi BP, Charabi BW, Klug TE, Jacobsen H, Johansen J, Kristensen CA, Andersen E, Andersen M, Bjørndal K
Eur Arch Otorhinolaryngol 2023 Jul;280(7):3405-3413. Epub 2023 Apr 13 doi: 10.1007/s00405-023-07940-y. PMID: 37052687Free PMC Article
Zhang J, Sun Y, Li Z, Feng H
Br J Oral Maxillofac Surg 2019 May;57(4):368-370. Epub 2019 Apr 8 doi: 10.1016/j.bjoms.2019.03.011. PMID: 30975511
Sykes AJ, Slevin NJ, Birzgalis AR, Gupta NK
Oral Oncol 1999 Mar;35(2):187-90. doi: 10.1016/s1368-8375(98)00099-2. PMID: 10435154
Heintz PW, Schmidt WA, Pommier RF, Vetto JT, DiTomasso JP
Acta Cytol 1998 Nov-Dec;42(6):1431-6. doi: 10.1159/000332180. PMID: 9850655

Therapy

Motohashi N, Wakabayashi H, Kurihara T, Fukushima H, Yamada T, Kawase M, Sohara Y, Tani S, Shirataki Y, Sakagami H, Satoh K, Nakashima H, Molnár A, Spengler G, Gyémánt N, Ugocsai K, Molnár J
Phytother Res 2004 Mar;18(3):212-23. doi: 10.1002/ptr.1426. PMID: 15103668

Prognosis

Westergaard-Nielsen M, Godballe C, Eriksen JG, Larsen SR, Kiss K, Agander T, Ulhøi BP, Charabi BW, Klug TE, Jacobsen H, Johansen J, Kristensen CA, Andersen E, Andersen M, Bjørndal K
Eur Arch Otorhinolaryngol 2023 Jul;280(7):3405-3413. Epub 2023 Apr 13 doi: 10.1007/s00405-023-07940-y. PMID: 37052687Free PMC Article
Liu S, Xu W, Liu L, Zhu Y, Wu Y, Lu H, Yang W, Zhang C
Oral Dis 2023 Nov;29(8):3298-3305. Epub 2022 Jul 19 doi: 10.1111/odi.14313. PMID: 35821655
Cho WK, Roh JL, Cho KJ, Choi SH, Nam SY, Kim SY
J Cancer Res Clin Oncol 2019 Apr;145(4):1055-1062. Epub 2019 Feb 26 doi: 10.1007/s00432-019-02876-5. PMID: 30806787
Yamada K, Honda K, Tamaki H, Tanaka S, Shinohara S, Takebayashi S, Tateya I, Kitamura M, Mizuta M, Maetani T, Kojima T, Kitani Y, Asato R, Ichimaru K, Kumabe Y, Ushiro K, Omori K
Auris Nasus Larynx 2018 Oct;45(5):1066-1072. Epub 2018 Feb 7 doi: 10.1016/j.anl.2018.01.011. PMID: 29428494
Sykes AJ, Slevin NJ, Birzgalis AR, Gupta NK
Oral Oncol 1999 Mar;35(2):187-90. doi: 10.1016/s1368-8375(98)00099-2. PMID: 10435154

Clinical prediction guides

Sajisevi M, Nguyen K, Callas P, Holcomb AJ, Vural E, Davis KP, Thomas CM, Plonowska-Hirschfeld KA, Stein JS, Eskander A, Kakarala K, Enepekides DJ, Hier MP, Ryan WR; American Head and Neck Society Salivary Gland Section, Asarkar AA, Aulet R, Bell RK, Blasco MA, Bowmaster VB, Burruss CP, Chung J, Chan K, Chang BA, Coffey CS, Cognetti DM, Cooper DJ, Cordero J, Donovan J, Du YJ, Dundar Y, Dedivitis RA, Edwards HA, Erovic BM, Feinberg PA, Garvey EA, Goldstein DP, Goodman JF, Goulart RN, Goyal N, Grasl S, Giurintano JP, Gupta N, Habib AM, Hackman TG, Hara JH, Henson C, Hinni ML, Hua N, Johnson-Obaseki S, Juloori A, Kalman NS, Kejner AE, Khaja SF, Ku JA, Lambert A, Luu BK, Magliocca KR, Dos Santos LRM, Michael C, Miles BA, de Melo GM, Moore MG, Morand GB, Moura K, Mukdad L, Noroozi H, Patel R, Paydarfar JA, Sadeghi N, Savaria FN, Schmitt NC, Shapiro J, Shaver TB, Stoeckli SJ, St John M, Stokes WA, Sulibhavi A, Tasoulas J, Vendra V, Vinh DB, Virgen CG, Wooten C, Woody NM, Young GD
JAMA Otolaryngol Head Neck Surg 2024 Feb 1;150(2):107-116. doi: 10.1001/jamaoto.2023.3952. PMID: 38095911Free PMC Article
Shiraishi T, Chikui T, Yoshida S, Okamura K, Hashimoto K, Fukui T, Kagawa T
Oral Radiol 2024 Apr;40(2):314-318. Epub 2023 Nov 30 doi: 10.1007/s11282-023-00724-4. PMID: 38032399
Cho WK, Roh JL, Cho KJ, Choi SH, Nam SY, Kim SY
J Cancer Res Clin Oncol 2019 Apr;145(4):1055-1062. Epub 2019 Feb 26 doi: 10.1007/s00432-019-02876-5. PMID: 30806787
Yamada K, Honda K, Tamaki H, Tanaka S, Shinohara S, Takebayashi S, Tateya I, Kitamura M, Mizuta M, Maetani T, Kojima T, Kitani Y, Asato R, Ichimaru K, Kumabe Y, Ushiro K, Omori K
Auris Nasus Larynx 2018 Oct;45(5):1066-1072. Epub 2018 Feb 7 doi: 10.1016/j.anl.2018.01.011. PMID: 29428494
Fujisawa S, Atsumi T, Kadoma Y, Sakagami H
Toxicology 2002 Aug 1;177(1):39-54. doi: 10.1016/s0300-483x(02)00194-4. PMID: 12126794

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