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Lung benign neoplasm

MedGen UID:
83393
•Concept ID:
C0345963
•
Neoplastic Process
Synonyms: Benign Lung Neoplasm; benign lung neoplasm; Benign Lung Tumor; benign lung tumor; benign lung tumour; Benign neoplasm of lung; Benign Neoplasm of Lung; benign neoplasm of lung; Benign Neoplasm of the Lung; benign neoplasm of the lung; Benign tumor of lung; Benign Tumor of Lung; benign tumor of lung; Benign Tumor of the Lung; benign tumor of the lung; benign tumour of lung; benign tumour of the lung; lung benign neoplasm
SNOMED CT: Benign neoplasm of lung (92196005); Benign tumor of lung (92196005)
 
Monarch Initiative: MONDO:0002732

Definition

A neoplasm that arises from the lung and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Professional guidelines

PubMed

SCLC: Epidemiology, Risk Factors, Genetic Susceptibility, Molecular Pathology, Screening, and Early Detection.
Wang Q, Gümüş ZH, Colarossi C, Memeo L, Wang X, Kong CY, Boffetta P
J Thorac Oncol 2023 Jan;18(1):31-46. Epub 2022 Oct 12 doi: 10.1016/j.jtho.2022.10.002. PMID: 36243387Free PMC Article
Lymphangioleiomyomatosis: pathogenesis, clinical features, diagnosis, and management.
McCarthy C, Gupta N, Johnson SR, Yu JJ, McCormack FX
Lancet Respir Med 2021 Nov;9(11):1313-1327. Epub 2021 Aug 27 doi: 10.1016/S2213-2600(21)00228-9. PMID: 34461049
Non-Small Cell Lung Cancer: Epidemiology, Screening, Diagnosis, and Treatment.
Duma N, Santana-Davila R, Molina JR
Mayo Clin Proc 2019 Aug;94(8):1623-1640. doi: 10.1016/j.mayocp.2019.01.013. PMID: 31378236

Recent clinical studies

Etiology

Guided Bronchoscopy for the Evaluation of Pulmonary Lesions: An Updated Meta-analysis.
Nadig TR, Thomas N, Nietert PJ, Lozier J, Tanner NT, Wang Memoli JS, Pastis NJ, Silvestri GA
Chest 2023 Jun;163(6):1589-1598. Epub 2023 Jan 11 doi: 10.1016/j.chest.2022.12.044. PMID: 36640994Free PMC Article
Neuroendocrine neoplasms of the lung and gastrointestinal system: convergent biology and a path to better therapies.
Kawasaki K, Rekhtman N, Quintanal-Villalonga Á, Rudin CM
Nat Rev Clin Oncol 2023 Jan;20(1):16-32. Epub 2022 Oct 28 doi: 10.1038/s41571-022-00696-0. PMID: 36307533
Role of biomarkers in lung nodule evaluation.
Sethi S, Cicenia J
Curr Opin Pulm Med 2022 Jul 1;28(4):275-281. doi: 10.1097/MCP.0000000000000886. PMID: 35749790
Guidelines for Pathologic Diagnosis of Malignant Mesothelioma 2017 Update of the Consensus Statement From the International Mesothelioma Interest Group.
Husain AN, Colby TV, Ordóñez NG, Allen TC, Attanoos RL, Beasley MB, Butnor KJ, Chirieac LR, Churg AM, Dacic S, Galateau-Sallé F, Gibbs A, Gown AM, Krausz T, Litzky LA, Marchevsky A, Nicholson AG, Roggli VL, Sharma AK, Travis WD, Walts AE, Wick MR
Arch Pathol Lab Med 2018 Jan;142(1):89-108. Epub 2017 Jul 7 doi: 10.5858/arpa.2017-0124-RA. PMID: 28686500
Congenital pulmonary airway malformations: state-of-the-art review for pediatrician's use.
Leblanc C, Baron M, Desselas E, Phan MH, Rybak A, Thouvenin G, Lauby C, Irtan S
Eur J Pediatr 2017 Dec;176(12):1559-1571. Epub 2017 Oct 19 doi: 10.1007/s00431-017-3032-7. PMID: 29046943

Diagnosis

Lung Nodules.
Am Fam Physician 2023 Mar;107(3):Online. PMID: 36920824
Diagnosis of Mesothelioma.
Fels Elliott DR, Jones KD
Surg Pathol Clin 2020 Mar;13(1):73-89. Epub 2019 Dec 3 doi: 10.1016/j.path.2019.10.001. PMID: 32005436
Spectrum of Lung Adenocarcinoma.
Hutchinson BD, Shroff GS, Truong MT, Ko JP
Semin Ultrasound CT MR 2019 Jun;40(3):255-264. Epub 2018 Nov 30 doi: 10.1053/j.sult.2018.11.009. PMID: 31200873
Carinal Pneumonectomy.
Mehran R, Deslauriers J
Thorac Surg Clin 2018 Aug;28(3):315-322. doi: 10.1016/j.thorsurg.2018.04.004. PMID: 30054069
Lung Cancer Biopsies.
Sharma A, Shepard JO
Radiol Clin North Am 2018 May;56(3):377-390. Epub 2018 Mar 7 doi: 10.1016/j.rcl.2018.01.001. PMID: 29622073

Therapy

AI Improves Nodule Detection on Chest Radiographs in a Health Screening Population: A Randomized Controlled Trial.
Nam JG, Hwang EJ, Kim J, Park N, Lee EH, Kim HJ, Nam M, Lee JH, Park CM, Goo JM
Radiology 2023 Apr;307(2):e221894. Epub 2023 Feb 7 doi: 10.1148/radiol.221894. PMID: 36749213
Blood-Based Biomarker Panel for Personalized Lung Cancer Risk Assessment.
Fahrmann JF, Marsh T, Irajizad E, Patel N, Murage E, Vykoukal J, Dennison JB, Do KA, Ostrin E, Spitz MR, Lam S, Shete S, Meza R, Tammemägi MC, Feng Z, Hanash SM
J Clin Oncol 2022 Mar 10;40(8):876-883. Epub 2022 Jan 7 doi: 10.1200/JCO.21.01460. PMID: 34995129Free PMC Article
Exercise and lung cancer surgery: A systematic review of randomized-controlled trials.
Himbert C, Klossner N, Coletta AM, Barnes CA, Wiskemann J, LaStayo PC, Varghese TK Jr, Ulrich CM
Crit Rev Oncol Hematol 2020 Dec;156:103086. Epub 2020 Sep 13 doi: 10.1016/j.critrevonc.2020.103086. PMID: 33038630Free PMC Article
Lung cancer staging: a concise update.
Rami-Porta R, Call S, Dooms C, Obiols C, Sánchez M, Travis WD, Vollmer I
Eur Respir J 2018 May;51(5) Epub 2018 May 17 doi: 10.1183/13993003.00190-2018. PMID: 29700105
Aerosolized chemotherapy.
Gagnadoux F, Hureaux J, Vecellio L, Urban T, Le Pape A, Valo I, Montharu J, Leblond V, Boisdron-Celle M, Lerondel S, Majoral C, Diot P, Racineux JL, Lemarie E
J Aerosol Med Pulm Drug Deliv 2008 Mar;21(1):61-70. doi: 10.1089/jamp.2007.0656. PMID: 18518832

Prognosis

Lung Cancer: Epidemiology and Screening.
Oliver AL
Surg Clin North Am 2022 Jun;102(3):335-344. Epub 2022 Apr 21 doi: 10.1016/j.suc.2021.12.001. PMID: 35671760
Cancer Statistics, 2021.
Siegel RL, Miller KD, Fuchs HE, Jemal A
CA Cancer J Clin 2021 Jan;71(1):7-33. Epub 2021 Jan 12 doi: 10.3322/caac.21654. PMID: 33433946
Progress in cancer mortality, incidence, and survival: a global overview.
Santucci C, Carioli G, Bertuccio P, Malvezzi M, Pastorino U, Boffetta P, Negri E, Bosetti C, La Vecchia C
Eur J Cancer Prev 2020 Sep;29(5):367-381. doi: 10.1097/CEJ.0000000000000594. PMID: 32740162
Global Cancer Incidence and Mortality Rates and Trends--An Update.
Torre LA, Siegel RL, Ward EM, Jemal A
Cancer Epidemiol Biomarkers Prev 2016 Jan;25(1):16-27. Epub 2015 Dec 14 doi: 10.1158/1055-9965.EPI-15-0578. PMID: 26667886
Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012.
Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, Parkin DM, Forman D, Bray F
Int J Cancer 2015 Mar 1;136(5):E359-86. Epub 2014 Oct 9 doi: 10.1002/ijc.29210. PMID: 25220842

Clinical prediction guides

A diagnostic classification of lung nodules using multiple-scale residual network.
Wang H, Zhu H, Ding L, Yang K
Sci Rep 2023 Jul 13;13(1):11322. doi: 10.1038/s41598-023-38350-z. PMID: 37443333Free PMC Article
Longitudinal lung cancer prediction convolutional neural network model improves the classification of indeterminate pulmonary nodules.
Paez R, Kammer MN, Balar A, Lakhani DA, Knight M, Rowe D, Xiao D, Heideman BE, Antic SL, Chen H, Chen SC, Peikert T, Sandler KL, Landman BA, Deppen SA, Grogan EL, Maldonado F
Sci Rep 2023 Apr 15;13(1):6157. doi: 10.1038/s41598-023-33098-y. PMID: 37061539Free PMC Article
Extravascular lung water monitoring for thoracic and lung transplant surgeries.
Assaad S, Kratzert WB, Perrino AC Jr
Curr Opin Anaesthesiol 2019 Feb;32(1):29-38. doi: 10.1097/ACO.0000000000000683. PMID: 30507676
Radiology in diffuse parenchymal lung disease and lung nodules.
Sverzellati N, Desai S
Eur Respir Rev 2017 Jun 30;26(144) Epub 2017 May 17 doi: 10.1183/16000617.0049-2017. PMID: 28515042Free PMC Article
LUCIS: lung cancer imaging studies.
Harders SW
Dan Med J 2012 Nov;59(11):B4542. PMID: 23171752

Recent systematic reviews

Diet as a Factor Supporting Lung Cancer Treatment-A Systematic Review.
Polański J, Świątoniowska-Lonc N, Kołaczyńska S, Chabowski M
Nutrients 2023 Mar 19;15(6) doi: 10.3390/nu15061477. PMID: 36986207Free PMC Article
Lung cancer risk prediction models based on pulmonary nodules: A systematic review.
Wu Z, Wang F, Cao W, Qin C, Dong X, Yang Z, Zheng Y, Luo Z, Zhao L, Yu Y, Xu Y, Li J, Tang W, Shen S, Wu N, Tan F, Li N, He J
Thorac Cancer 2022 Mar;13(5):664-677. Epub 2022 Feb 8 doi: 10.1111/1759-7714.14333. PMID: 35137543Free PMC Article
Consumption of red meat and processed meat and cancer incidence: a systematic review and meta-analysis of prospective studies.
Farvid MS, Sidahmed E, Spence ND, Mante Angua K, Rosner BA, Barnett JB
Eur J Epidemiol 2021 Sep;36(9):937-951. Epub 2021 Aug 29 doi: 10.1007/s10654-021-00741-9. PMID: 34455534
Exercise and lung cancer surgery: A systematic review of randomized-controlled trials.
Himbert C, Klossner N, Coletta AM, Barnes CA, Wiskemann J, LaStayo PC, Varghese TK Jr, Ulrich CM
Crit Rev Oncol Hematol 2020 Dec;156:103086. Epub 2020 Sep 13 doi: 10.1016/j.critrevonc.2020.103086. PMID: 33038630Free PMC Article
COPD, emphysema and the onset of lung cancer. A systematic review.
Mouronte-Roibás C, Leiro-Fernández V, Fernández-Villar A, Botana-Rial M, Ramos-Hernández C, Ruano-Ravina A
Cancer Lett 2016 Nov 28;382(2):240-244. Epub 2016 Sep 22 doi: 10.1016/j.canlet.2016.09.002. PMID: 27666776

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