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Childhood Embryonal Rhabdomyosarcoma

MedGen UID:
83530
•Concept ID:
C0279612
•
Neoplastic Process
Synonyms: Embryonal Childhood Rhabdomyosarcoma; Pediatric Embryonal Rhabdomyosarcoma

Definition

A poorly circumscribed morphologic variant of rhabdomyosarcoma occurring in children. The neoplasm is characterized by the presence of primitive skeletal muscle in any stage of myogenesis. [from NCI]

Professional guidelines

PubMed

Radiotherapy in the Management of Childhood Rhabdomyosarcoma.
Mandeville HC
Clin Oncol (R Coll Radiol) 2019 Jul;31(7):462-470. Epub 2019 Apr 13 doi: 10.1016/j.clon.2019.03.047. PMID: 30992168
Diagnosis and Management of Rhabdomyosarcoma in Children and Adolescents: ICMR Consensus Document.
Panda SP, Chinnaswamy G, Vora T, Prasad M, Bansal D, Kapoor G, Radhakrishnan V, Agarwala S, Laskar S, Arora B, Kaur T, Rath GK, Bakhshi S
Indian J Pediatr 2017 May;84(5):393-402. Epub 2017 Apr 5 doi: 10.1007/s12098-017-2315-3. PMID: 28378141
Molecular diagnostics in the management of rhabdomyosarcoma.
Arnold MA, Barr FG
Expert Rev Mol Diagn 2017 Feb;17(2):189-194. Epub 2017 Jan 6 doi: 10.1080/14737159.2017.1275965. PMID: 28058850Free PMC Article

Recent clinical studies

Etiology

A Case of Pheochromocytoma as a Subsequent Neoplasm in a Survivor of Childhood Embryonal Rhabdomyosarcoma.
Rodwin RL, Janardan SK, Hofstatter EW, Kadan-Lottick NS
J Pediatr Hematol Oncol 2022 Mar 1;44(2):e585-e588. doi: 10.1097/MPH.0000000000002270. PMID: 35200227Free PMC Article
Characteristics of gastrointestinal stromal tumors in a Middle Eastern population.
Barakat FH, Haddad HA, Matalka II, Al-Orjani MS, Al-Masri MM, Sughayer MA
Saudi Med J 2010 Jul;31(7):797-802. PMID: 20635015

Diagnosis

A Case of Pheochromocytoma as a Subsequent Neoplasm in a Survivor of Childhood Embryonal Rhabdomyosarcoma.
Rodwin RL, Janardan SK, Hofstatter EW, Kadan-Lottick NS
J Pediatr Hematol Oncol 2022 Mar 1;44(2):e585-e588. doi: 10.1097/MPH.0000000000002270. PMID: 35200227Free PMC Article

Therapy

Current trends in treatment of childhood rhabdomyosarcoma of lower genitourinary tract.
Belman AB, Baum ES
Urology 1976 Jul;8(1):31-4. doi: 10.1016/0090-4295(76)90048-0. PMID: 941356

Prognosis

Alternative prognostic factors in pediatric embryonal rhabdomyosarcoma: Nm23 expression, proliferative activity and angiogenesis.
Diniz G, Aktaş S, Ortaç R, Erbay A, Vergin C, Ergin M
Turk J Pediatr 2004 Jul-Sep;46(3):239-44. PMID: 15503477

Clinical prediction guides

Alternative prognostic factors in pediatric embryonal rhabdomyosarcoma: Nm23 expression, proliferative activity and angiogenesis.
Diniz G, Aktaş S, Ortaç R, Erbay A, Vergin C, Ergin M
Turk J Pediatr 2004 Jul-Sep;46(3):239-44. PMID: 15503477

Supplemental Content

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