Full Report

Format

Full Report
Summary (Text)
Summary (XML)

Send to:

Choose Destination

File
Clipboard
Collections

Childhood Soft Tissue Sarcoma

MedGen UID:: 66311
•Concept ID:: C0220645
•: Neoplastic Process

Synonyms:

Childhood Sarcoma of Soft Tissue; Childhood Sarcoma of the Soft Tissue; Pediatric Sarcoma of Soft Tissue; Pediatric Sarcoma of the Soft Tissue; Pediatric Soft Tissue Sarcoma

Definition

Soft tissue sarcoma occurring in childhood. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVChildhood Soft Tissue Sarcoma

Pathological process
- Disease
  - Neoplasm
    - Neoplasm by Special Category
      - Childhood neoplasm
        Childhood malignant neoplasm
        Childhood Soft Tissue Sarcoma
        Childhood Alveolar Soft Part Sarcoma
        Childhood Clear Cell Sarcoma of Soft Tissue
        Childhood Desmoplastic Small Round Cell Tumor
        Childhood epithelioid sarcoma
        Childhood extraosseous osteosarcoma
        Childhood Leiomyosarcoma
        Childhood Small Intestinal Leiomyosarcoma
        Childhood Rhabdomyosarcoma
        Childhood Alveolar Rhabdomyosarcoma
        Childhood Embryonal Rhabdomyosarcoma
        Childhood botryoid rhabdomyosarcoma
        Childhood pleomorphic rhabdomyosarcoma
        Childhood Rhabdomyosarcoma with Mixed Embryonal and Alveolar Features
        Childhood spindle cell rhabdomyosarcoma
        Localized Childhood Rhabdomyosarcoma
        Recurrent Childhood Rhabdomyosarcoma
        Childhood Synovial Sarcoma
        Childhood Undifferentiated Pleomorphic Sarcoma
        Clear cell sarcoma of kidney
        Localized Childhood Soft Tissue Sarcoma
        Metastatic Childhood Soft Tissue Sarcoma
        Pediatric mesenchymal chondrosarcoma
        Pediatric myxoid chondrosarcoma
        Recurrent Childhood Soft Tissue Sarcoma

Professional guidelines

PubMed

Targeting Hippo-Dependent and Hippo-Independent YAP1 Signaling for the Treatment of Childhood Rhabdomyosarcoma.

Slemmons KK, Yeung C, Baumgart JT, Juarez JOM, McCalla A, Helman LJ
Cancer Res 2020 Jul 15;80(14):3046-3056. Epub 2020 Apr 30 doi: 10.1158/0008-5472.CAN-19-3853. PMID: 32354737

Second malignant neoplasms in children after treatment of soft tissue sarcoma.

Rich DC, Corpron CA, Smith MB, Black CT, Lally KP, Andrassy RJ
J Pediatr Surg 1997 Feb;32(2):369-72. doi: 10.1016/s0022-3468(97)90213-x. PMID: 9044156

See all (2)

Recent clinical studies

Etiology

Neurocognitive and psychosocial outcomes in adult survivors of childhood soft-tissue sarcoma: A report from the St. Jude Lifetime Cohort.

Tonning Olsson I, Brinkman TM, Wang M, Ehrhardt MJ, Banerjee P, Mulrooney DA, Huang IC, Ness KK, Bishop MW, Srivastava D, Robison LL, Hudson MM, Krull KR
Cancer 2020 Apr 1;126(7):1576-1584. Epub 2020 Jan 8 doi: 10.1002/cncr.32694. PMID: 31913509 Free PMC Article

Cooperative trial CWS-91 for localized soft tissue sarcoma in children, adolescents, and young adults.

Dantonello TM, Int-Veen C, Harms D, Leuschner I, Schmidt BF, Herbst M, Juergens H, Scheel-Walter HG, Bielack SS, Klingebiel T, Dickerhoff R, Kirsch S, Brecht I, Schmelzle R, Greulich M, Gadner H, Greiner J, Marky I, Treuner J, Koscielniak E
J Clin Oncol 2009 Mar 20;27(9):1446-55. Epub 2009 Feb 17 doi: 10.1200/JCO.2007.15.0466. PMID: 19224858

Interstitial brachytherapy for childhood soft tissue sarcoma.

Laskar S, Bahl G, Ann Muckaden M, Puri A, Agarwal MG, Patil N, Shrivastava SK, Dinshaw KA
Pediatr Blood Cancer 2007 Oct 15;49(5):649-55. doi: 10.1002/pbc.21118. PMID: 17226842

Childhood soft tissue sarcoma: a 20-year experience.

Marcus KC, Grier HE, Shamberger RC, Gebhardt MC, Perez-Atayde A, Silver B, Tarbell NJ
J Pediatr 1997 Oct;131(4):603-7. doi: 10.1016/s0022-3476(97)70070-2. PMID: 9386667

Cancer in survivors of childhood soft tissue sarcoma and their relatives.

Strong LC, Stine M, Norsted TL
J Natl Cancer Inst 1987 Dec;79(6):1213-20. PMID: 3480372

See all (22)

Diagnosis

Defining an embryonal rhabdomyosarcoma endotype.

Ricker CA, Crawford K, Matlock K, Lathara M, Seguin B, Rudzinski ER, Berlow NE, Keller C
Cold Spring Harb Mol Case Stud 2020 Apr;6(2) Epub 2020 Apr 1 doi: 10.1101/mcs.a005066. PMID: 32238403 Free PMC Article

Neurocognitive and psychosocial outcomes in adult survivors of childhood soft-tissue sarcoma: A report from the St. Jude Lifetime Cohort.

Childhood soft tissue sarcoma: a 20-year experience.

Marcus KC, Grier HE, Shamberger RC, Gebhardt MC, Perez-Atayde A, Silver B, Tarbell NJ
J Pediatr 1997 Oct;131(4):603-7. doi: 10.1016/s0022-3476(97)70070-2. PMID: 9386667

Malformations in children with soft tissue sarcoma and in their parents and siblings.

Hartley AL, Birch JM, Blair V, Kelsey AM
Paediatr Perinat Epidemiol 1994 Oct;8(4):423-32. doi: 10.1111/j.1365-3016.1994.tb00481.x. PMID: 7870626

Cancer in survivors of childhood soft tissue sarcoma and their relatives.

Strong LC, Stine M, Norsted TL
J Natl Cancer Inst 1987 Dec;79(6):1213-20. PMID: 3480372

See all (18)

Therapy

Targeting KDM4 for treating PAX3-FOXO1-driven alveolar rhabdomyosarcoma.

Singh S, Abu-Zaid A, Jin H, Fang J, Wu Q, Wang T, Feng H, Quarni W, Shao Y, Maxham L, Abdolvahabi A, Yun MK, Vaithiyalingam S, Tan H, Bowling J, Honnell V, Young B, Guo Y, Bajpai R, Pruett-Miller SM, Grosveld GC, Hatley M, Xu B, Fan Y, Wu G, Chen EY, Chen T, Lewis PW, Rankovic Z, Li Y, Murphy AJ, Easton J, Peng J, Chen X, Wang R, White SW, Davidoff AM, Yang J
Sci Transl Med 2022 Jul 13;14(653):eabq2096. doi: 10.1126/scitranslmed.abq2096. PMID: 35857643 Free PMC Article

Defining an embryonal rhabdomyosarcoma endotype.

Neurocognitive and psychosocial outcomes in adult survivors of childhood soft-tissue sarcoma: A report from the St. Jude Lifetime Cohort.

Cooperative trial CWS-91 for localized soft tissue sarcoma in children, adolescents, and young adults.

Interstitial brachytherapy for childhood soft tissue sarcoma.

Laskar S, Bahl G, Ann Muckaden M, Puri A, Agarwal MG, Patil N, Shrivastava SK, Dinshaw KA
Pediatr Blood Cancer 2007 Oct 15;49(5):649-55. doi: 10.1002/pbc.21118. PMID: 17226842

See all (9)

Prognosis

Defining an embryonal rhabdomyosarcoma endotype.

Interstitial brachytherapy for childhood soft tissue sarcoma.

Laskar S, Bahl G, Ann Muckaden M, Puri A, Agarwal MG, Patil N, Shrivastava SK, Dinshaw KA
Pediatr Blood Cancer 2007 Oct 15;49(5):649-55. doi: 10.1002/pbc.21118. PMID: 17226842

Childhood soft tissue sarcoma: a 20-year experience.

Marcus KC, Grier HE, Shamberger RC, Gebhardt MC, Perez-Atayde A, Silver B, Tarbell NJ
J Pediatr 1997 Oct;131(4):603-7. doi: 10.1016/s0022-3476(97)70070-2. PMID: 9386667

Malformations in children with soft tissue sarcoma and in their parents and siblings.

Hartley AL, Birch JM, Blair V, Kelsey AM
Paediatr Perinat Epidemiol 1994 Oct;8(4):423-32. doi: 10.1111/j.1365-3016.1994.tb00481.x. PMID: 7870626

Cancer in survivors of childhood soft tissue sarcoma and their relatives.

Strong LC, Stine M, Norsted TL
J Natl Cancer Inst 1987 Dec;79(6):1213-20. PMID: 3480372

See all (16)

Clinical prediction guides

Neurocognitive and psychosocial outcomes in adult survivors of childhood soft-tissue sarcoma: A report from the St. Jude Lifetime Cohort.

The risk of developing second cancers among survivors of childhood soft tissue sarcoma.

Cohen RJ, Curtis RE, Inskip PD, Fraumeni JF Jr
Cancer 2005 Jun 1;103(11):2391-6. doi: 10.1002/cncr.21040. PMID: 15852362

Childhood soft tissue sarcoma: a 20-year experience.

Marcus KC, Grier HE, Shamberger RC, Gebhardt MC, Perez-Atayde A, Silver B, Tarbell NJ
J Pediatr 1997 Oct;131(4):603-7. doi: 10.1016/s0022-3476(97)70070-2. PMID: 9386667

Segregation analysis of cancer in families of childhood soft-tissue-sarcoma patients.

Lustbader ED, Williams WR, Bondy ML, Strom S, Strong LC
Am J Hum Genet 1992 Aug;51(2):344-56. PMID: 1642235 Free PMC Article

Cancer in survivors of childhood soft tissue sarcoma and their relatives.

Strong LC, Stine M, Norsted TL
J Natl Cancer Inst 1987 Dec;79(6):1213-20. PMID: 3480372

See all (13)

Recent systematic reviews

Adult parameningial alveolar rhabdomyosarcoma: Case report and literature review.

Barthère X, Guillerm S, Quero L, Le Maignan C, Torossian N, Verillaud B, Itti R, Hennequin C
Cancer Radiother 2020 Dec;24(8):870-875. Epub 2020 Nov 7 doi: 10.1016/j.canrad.2020.03.015. PMID: 33172776

See all (1)

MedGen

National Center for Biotechnology Information

Send to:

Childhood Soft Tissue Sarcoma

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Practice guidelines

Related information

Recent activity