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Benign neoplasm of sublingual gland

MedGen UID:
83858
•Concept ID:
C0347208
•
Neoplastic Process
Synonyms: Benign Neoplasm of Sublingual Gland; benign neoplasm of sublingual gland; Benign Neoplasm of the Sublingual Gland; benign neoplasm of the sublingual gland; Benign Sublingual Gland Neoplasm; benign sublingual gland neoplasm; Benign Sublingual Gland Tumor; benign sublingual gland tumor; benign sublingual gland tumour; Benign tumor of sublingual gland; Benign Tumor of Sublingual Gland; benign tumor of sublingual gland; Benign Tumor of the Sublingual Gland; benign tumor of the sublingual gland; benign tumour of sublingual gland; benign tumour of the sublingual gland; sublingual gland benign neoplasm
SNOMED CT: Benign neoplasm of sublingual gland (92413008); Benign tumor of sublingual gland (92413008)
 
Monarch Initiative: MONDO:0021495

Definition

A neoplasm that arises from the sublingual gland and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign neoplasm of sublingual gland

Professional guidelines

PubMed

Salivary gland cancer: ESMO-European Reference Network on Rare Adult Solid Cancers (EURACAN) Clinical Practice Guideline for diagnosis, treatment and follow-up.
van Herpen C, Vander Poorten V, Skalova A, Terhaard C, Maroldi R, van Engen A, Baujat B, Locati LD, Jensen AD, Smeele L, Hardillo J, Martineau VC, Trama A, Kinloch E, Even C, Machiels JP; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
ESMO Open 2022 Dec;7(6):100602. Epub 2022 Nov 2 doi: 10.1016/j.esmoop.2022.100602. PMID: 36567082Free PMC Article
Management of Mucoceles, Sialoceles, and Ranulas.
Bowers EMR, Schaitkin B
Otolaryngol Clin North Am 2021 Jun;54(3):543-551. doi: 10.1016/j.otc.2021.03.002. PMID: 34024482
Guidelines for Clinical Target Volume Definition for Perineural Spread of Major Salivary Gland Cancers.
Armstrong K, Ward J, Hughes NM, Mihai A, Blayney A, Mascott C, Kileen R, Armstrong J
Clin Oncol (R Coll Radiol) 2018 Dec;30(12):773-779. Epub 2018 Sep 14 doi: 10.1016/j.clon.2018.08.018. PMID: 30224202

Recent clinical studies

Etiology

Lymphomas of the salivary glands: a systematic review.
Al-Khafaf AE, Al-Shahrestani F, Baysal Y, Rahbek Gjerdrum LM, Heegaard S, Pedersen LM, Homøe P
Acta Otolaryngol 2023 Jul-Aug;143(7):610-616. Epub 2023 Aug 12 doi: 10.1080/00016489.2023.2226689. PMID: 37572309
Pediatric primary salivary gland tumors.
Jesberg P, Monzon A, Gitomer SA, Herrmann BW
Am J Otolaryngol 2023 Sep-Oct;44(5):103948. Epub 2023 Jun 8 doi: 10.1016/j.amjoto.2023.103948. PMID: 37352681
Salivary gland cancer: ESMO-European Reference Network on Rare Adult Solid Cancers (EURACAN) Clinical Practice Guideline for diagnosis, treatment and follow-up.
van Herpen C, Vander Poorten V, Skalova A, Terhaard C, Maroldi R, van Engen A, Baujat B, Locati LD, Jensen AD, Smeele L, Hardillo J, Martineau VC, Trama A, Kinloch E, Even C, Machiels JP; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
ESMO Open 2022 Dec;7(6):100602. Epub 2022 Nov 2 doi: 10.1016/j.esmoop.2022.100602. PMID: 36567082Free PMC Article
Sublingual gland neoplasms: clinicopathological study of 8 cases.
Gontarz M, Urbańska-Gąsiorowska M, Bargiel J, Gąsiorowski K, Marecik T, Szczurowski P, Zapała J, Wyszyńska-Pawelec G
Med Oral Patol Oral Cir Bucal 2021 Sep 1;26(5):e626-e631. doi: 10.4317/medoral.24634. PMID: 34415003Free PMC Article
Guidelines for Clinical Target Volume Definition for Perineural Spread of Major Salivary Gland Cancers.
Armstrong K, Ward J, Hughes NM, Mihai A, Blayney A, Mascott C, Kileen R, Armstrong J
Clin Oncol (R Coll Radiol) 2018 Dec;30(12):773-779. Epub 2018 Sep 14 doi: 10.1016/j.clon.2018.08.018. PMID: 30224202

Diagnosis

Pediatric Salivary Gland Pathology.
Amin SN, Patterson KT, Cvancara DJ, Dahl JP
Oral Maxillofac Surg Clin North Am 2024 Aug;36(3):317-332. Epub 2024 May 8 doi: 10.1016/j.coms.2024.02.001. PMID: 38724422
Salivary gland cancer: ESMO-European Reference Network on Rare Adult Solid Cancers (EURACAN) Clinical Practice Guideline for diagnosis, treatment and follow-up.
van Herpen C, Vander Poorten V, Skalova A, Terhaard C, Maroldi R, van Engen A, Baujat B, Locati LD, Jensen AD, Smeele L, Hardillo J, Martineau VC, Trama A, Kinloch E, Even C, Machiels JP; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
ESMO Open 2022 Dec;7(6):100602. Epub 2022 Nov 2 doi: 10.1016/j.esmoop.2022.100602. PMID: 36567082Free PMC Article
Salivary Gland Malignancies.
Carlson ER, Schlieve T
Oral Maxillofac Surg Clin North Am 2019 Feb;31(1):125-144. doi: 10.1016/j.coms.2018.08.007. PMID: 30449524
Plunging ranula.
Kalra V, Mirza K, Malhotra A
J Radiol Case Rep 2011;5(6):18-24. Epub 2011 Jun 1 doi: 10.3941/jrcr.v5i6.682. PMID: 22470797Free PMC Article
Salivary glands.
Silvers AR, Som PM
Radiol Clin North Am 1998 Sep;36(5):941-66, vi. doi: 10.1016/s0033-8389(05)70070-1. PMID: 9747195

Therapy

Delayed Sublingual Edema Following Neonatal Mandibular Distraction Osteogenesis.
Miller EM, Jungbauer WN Jr, Carroll WW, Pecha PP
J Craniofac Surg 2023 Sep 1;34(6):e612-e614. Epub 2023 Jul 27 doi: 10.1097/SCS.0000000000009554. PMID: 37497798
Transoral Complete vs Partial Excision of the Sublingual Gland for Plunging Ranula.
Roh JL
Otolaryngol Head Neck Surg 2022 Sep;167(3):479-483. Epub 2021 Dec 21 doi: 10.1177/01945998211067500. PMID: 34932413
A retrospective multicenter study of sublingual gland carcinoma in Japan.
Kojima T, Hori R, Tanaka S, Tamaki H, Asato R, Kitamura M, Tateya I, Shinohara S, Takebayashi S, Maetani T, Kitani Y, Kumabe Y, Ushiro K, Ichimaru K, Honda K, Mizuta M, Yamada K, Omori K
Auris Nasus Larynx 2020 Feb;47(1):111-115. Epub 2019 May 17 doi: 10.1016/j.anl.2019.04.006. PMID: 31104870
Excision of sublingual gland as treatment for ranulas in pediatric patients.
Nguyen BN, Malone BN, Sidman JD, Barnett Roby B
Int J Pediatr Otorhinolaryngol 2017 Jun;97:154-156. Epub 2017 Apr 5 doi: 10.1016/j.ijporl.2017.04.003. PMID: 28483227
NUT Midline Carcinoma of the Sublingual Gland: Clinical Presentation and Review.
Seim NB, Philips RHW, Schoenfield L, Teknos TN, Rocco JW, Agrawal A, Ozer E, Carrau RL, Kang SY, Old MO
Head Neck Pathol 2017 Dec;11(4):460-468. Epub 2017 Mar 27 doi: 10.1007/s12105-017-0809-y. PMID: 28349372Free PMC Article

Prognosis

Lymphomas of the salivary glands: a systematic review.
Al-Khafaf AE, Al-Shahrestani F, Baysal Y, Rahbek Gjerdrum LM, Heegaard S, Pedersen LM, Homøe P
Acta Otolaryngol 2023 Jul-Aug;143(7):610-616. Epub 2023 Aug 12 doi: 10.1080/00016489.2023.2226689. PMID: 37572309
Salivary gland cancer: ESMO-European Reference Network on Rare Adult Solid Cancers (EURACAN) Clinical Practice Guideline for diagnosis, treatment and follow-up.
van Herpen C, Vander Poorten V, Skalova A, Terhaard C, Maroldi R, van Engen A, Baujat B, Locati LD, Jensen AD, Smeele L, Hardillo J, Martineau VC, Trama A, Kinloch E, Even C, Machiels JP; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
ESMO Open 2022 Dec;7(6):100602. Epub 2022 Nov 2 doi: 10.1016/j.esmoop.2022.100602. PMID: 36567082Free PMC Article
Sublingual gland neoplasms: clinicopathological study of 8 cases.
Gontarz M, Urbańska-Gąsiorowska M, Bargiel J, Gąsiorowski K, Marecik T, Szczurowski P, Zapała J, Wyszyńska-Pawelec G
Med Oral Patol Oral Cir Bucal 2021 Sep 1;26(5):e626-e631. doi: 10.4317/medoral.24634. PMID: 34415003Free PMC Article
Guidelines for Clinical Target Volume Definition for Perineural Spread of Major Salivary Gland Cancers.
Armstrong K, Ward J, Hughes NM, Mihai A, Blayney A, Mascott C, Kileen R, Armstrong J
Clin Oncol (R Coll Radiol) 2018 Dec;30(12):773-779. Epub 2018 Sep 14 doi: 10.1016/j.clon.2018.08.018. PMID: 30224202
Sublingual gland.
Batsakis JG
Ann Otol Rhinol Laryngol 1991 Jun;100(6):521-2. doi: 10.1177/000348949110000618. PMID: 2058996

Clinical prediction guides

Pediatric primary salivary gland tumors.
Jesberg P, Monzon A, Gitomer SA, Herrmann BW
Am J Otolaryngol 2023 Sep-Oct;44(5):103948. Epub 2023 Jun 8 doi: 10.1016/j.amjoto.2023.103948. PMID: 37352681
Molecular chaperones in tumors of salivary glands.
Basset CA, Cappello F, Rappa F, Lentini VL, Jurjus AR, Conway de Macario E, Macario AJL, Leone A
J Mol Histol 2020 Apr;51(2):109-115. Epub 2020 Apr 16 doi: 10.1007/s10735-020-09871-y. PMID: 32300923
A retrospective multicenter study of sublingual gland carcinoma in Japan.
Kojima T, Hori R, Tanaka S, Tamaki H, Asato R, Kitamura M, Tateya I, Shinohara S, Takebayashi S, Maetani T, Kitani Y, Kumabe Y, Ushiro K, Ichimaru K, Honda K, Mizuta M, Yamada K, Omori K
Auris Nasus Larynx 2020 Feb;47(1):111-115. Epub 2019 May 17 doi: 10.1016/j.anl.2019.04.006. PMID: 31104870
Margins for Benign Salivary Gland Neoplasms of the Head and Neck.
Carlson ER, McCoy JM
Oral Maxillofac Surg Clin North Am 2017 Aug;29(3):325-340. doi: 10.1016/j.coms.2017.03.009. PMID: 28709532
Pitfalls in the staging of cancer of the major salivary gland neoplasms.
Friedman ER, Saindane AM
Neuroimaging Clin N Am 2013 Feb;23(1):107-22. doi: 10.1016/j.nic.2012.08.009. PMID: 23199664

Recent systematic reviews

Lung cancer metastasizing to salivary glands: Systematic review.
Gupta S, Brar SK, Shubha K, Kaur A, Basavaraju S, Kedia NB, Garewal NK, Kaur M, Singh R
J Cancer Res Ther 2023 Jan 1;19(Suppl 2):S490-S498. Epub 2023 Feb 1 doi: 10.4103/jcrt.jcrt_2699_22. PMID: 38384010
Lymphomas of the salivary glands: a systematic review.
Al-Khafaf AE, Al-Shahrestani F, Baysal Y, Rahbek Gjerdrum LM, Heegaard S, Pedersen LM, Homøe P
Acta Otolaryngol 2023 Jul-Aug;143(7):610-616. Epub 2023 Aug 12 doi: 10.1080/00016489.2023.2226689. PMID: 37572309
Diagnosis and management of congenital floor of mouth masses: A systematic review.
Lucas JP, Allen M, Siegel B, Gonik N
Int J Pediatr Otorhinolaryngol 2021 Jan;140:110541. Epub 2020 Dec 1 doi: 10.1016/j.ijporl.2020.110541. PMID: 33296834
Elective neck dissection in patients with salivary gland carcinoma: A systematic review and meta-analysis.
Westergaard-Nielsen M, Rosenberg T, Gerke O, Dyrvig AK, Godballe C, Bjørndal K
J Oral Pathol Med 2020 Aug;49(7):606-616. Epub 2020 Jun 14 doi: 10.1111/jop.13034. PMID: 32430929
Comparison of outcomes of treatment for ranula: a proportion meta-analysis.
Chung YS, Cho Y, Kim BH
Br J Oral Maxillofac Surg 2019 Sep;57(7):620-626. Epub 2019 Jun 22 doi: 10.1016/j.bjoms.2019.06.005. PMID: 31239229

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