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Abnormal circulating chemokine concentration

MedGen UID:
869114
•Concept ID:
C4023532
•
Anatomical Abnormality
Synonym: Abnormality of chemokine secretion
 
HPO: HP:0011115

Definition

An abnormality in the production or cellular release of a chemokine (a class of cytokines). [from HPO]

Professional guidelines

PubMed

The Architecture of Circulating Immune Cells Is Dysregulated in People Living With HIV on Long Term Antiretroviral Treatment and Relates With Markers of the HIV-1 Reservoir, Cytomegalovirus, and Microbial Translocation.
Van de Wijer L, van der Heijden WA, Ter Horst R, Jaeger M, Trypsteen W, Rutsaert S, van Cranenbroek B, van Rijssen E, Joosten I, Joosten L, Vandekerckhove L, Schoofs T, van Lunzen J, Netea MG, Koenen HJPM, van der Ven AJAM, de Mast Q
Front Immunol 2021;12:661990. Epub 2021 Apr 19 doi: 10.3389/fimmu.2021.661990. PMID: 33953724Free PMC Article

Recent clinical studies

Etiology

Preeclampsia at term: evidence of disease heterogeneity based on the profile of circulating cytokines and angiogenic factors.
Chaiworapongsa T, Romero R, Gomez-Lopez N, Suksai M, Gallo DM, Jung E, Berry SM, Awonuga A, Tarca AL, Bryant DR
Am J Obstet Gynecol 2024 Apr;230(4):450.e1-450.e18. Epub 2023 Oct 6 doi: 10.1016/j.ajog.2023.10.002. PMID: 37806612Free PMC Article
Cardiovascular involvement in psoriatic arthritis.
Atzeni F, Turiel M, Boccassini L, Sitia S, Tomasoni L, Battellino M, Marchesoni A, De Gennaro Colonna V, Sarzi-Puttini P
Reumatismo 2011 Nov 9;63(3):148-54. doi: 10.4081/reumatismo.2011.148. PMID: 22257915
Influence of two perfusion strategies on oxygen metabolism in paediatric cardiac surgery. Evaluation of the high-flow, low-resistance technique.
Schindler E, Photiadis J, Lagudka S, Fink C, Hraska V, Asfour B
Eur J Cardiothorac Surg 2010 Mar;37(3):651-7. Epub 2009 Sep 19 doi: 10.1016/j.ejcts.2009.07.050. PMID: 19766503
Blood compatibility of two different types of membrane oxygenator during cardiopulmonary bypass in infants.
Gu YJ, Boonstra PW, Akkerman C, Mungroop H, Tigchelaar I, Van Oeveren W
Int J Artif Organs 1994 Oct;17(10):543-8. PMID: 7896428
Interleukin-8 receptors in normal and psoriatic polymorphonuclear leukocytes.
Arenberger P, Kemény L, Süss R, Michel G, Peter RU, Ruzicka T
Acta Derm Venereol 1992 Sep;72(5):334-6. PMID: 1361277

Diagnosis

The evaluation of PD-1 and Tim-3 expression besides their related miRNAs in PBMCs of women with recurrent pregnancy loss.
Ahmadi H, Soltani-Zangbar MS, Yousefi M, Baradaran B, Bromand S, Aghebati-Maleki L, Szekeres-Bartho J
Immunol Lett 2024 Apr;266:106837. Epub 2024 Jan 23 doi: 10.1016/j.imlet.2024.106837. PMID: 38266686
The role of chemerin in the pathogenesis of cholelithiasis in children and adolescents.
Zdanowicz K, Ryzko J, Bobrus-Chociej A, Wojtkowska M, Lebensztejn DM
J Paediatr Child Health 2021 Mar;57(3):371-375. Epub 2020 Oct 11 doi: 10.1111/jpc.15223. PMID: 33043555
Chemokine levels predict progressive liver disease in Down syndrome patients with transient abnormal myelopoiesis.
Kinjo T, Inoue H, Kusuda T, Fujiyoshi J, Ochiai M, Takahata Y, Honjo S, Koga Y, Hara T, Ohga S
Pediatr Neonatol 2019 Aug;60(4):382-388. Epub 2018 Sep 24 doi: 10.1016/j.pedneo.2018.09.005. PMID: 30314728
Loss of CXCR3 expression on memory B cells in individuals with long-standing type 1 diabetes.
Powell WE, Hanna SJ, Hocter CN, Robinson E, Davies J, Dunseath GJ, Luzio S, Farewell D, Wen L, Dayan CM, Price DA, Ladell K, Wong FS
Diabetologia 2018 Aug;61(8):1794-1803. Epub 2018 Jun 7 doi: 10.1007/s00125-018-4651-x. PMID: 29881878Free PMC Article
Interleukin-8 receptors in normal and psoriatic polymorphonuclear leukocytes.
Arenberger P, Kemény L, Süss R, Michel G, Peter RU, Ruzicka T
Acta Derm Venereol 1992 Sep;72(5):334-6. PMID: 1361277

Therapy

The Architecture of Circulating Immune Cells Is Dysregulated in People Living With HIV on Long Term Antiretroviral Treatment and Relates With Markers of the HIV-1 Reservoir, Cytomegalovirus, and Microbial Translocation.
Van de Wijer L, van der Heijden WA, Ter Horst R, Jaeger M, Trypsteen W, Rutsaert S, van Cranenbroek B, van Rijssen E, Joosten I, Joosten L, Vandekerckhove L, Schoofs T, van Lunzen J, Netea MG, Koenen HJPM, van der Ven AJAM, de Mast Q
Front Immunol 2021;12:661990. Epub 2021 Apr 19 doi: 10.3389/fimmu.2021.661990. PMID: 33953724Free PMC Article
Cardiovascular involvement in psoriatic arthritis.
Atzeni F, Turiel M, Boccassini L, Sitia S, Tomasoni L, Battellino M, Marchesoni A, De Gennaro Colonna V, Sarzi-Puttini P
Reumatismo 2011 Nov 9;63(3):148-54. doi: 10.4081/reumatismo.2011.148. PMID: 22257915
Influence of two perfusion strategies on oxygen metabolism in paediatric cardiac surgery. Evaluation of the high-flow, low-resistance technique.
Schindler E, Photiadis J, Lagudka S, Fink C, Hraska V, Asfour B
Eur J Cardiothorac Surg 2010 Mar;37(3):651-7. Epub 2009 Sep 19 doi: 10.1016/j.ejcts.2009.07.050. PMID: 19766503
Release of interleukin-8 and calprotectin during and after paediatric cardiopulmonary bypass with and without ultrafiltration.
Saatvedt K, Lindberg H, Geiran OR, Michelsen S, Pedersen T, Seem E, Fagerhol M
Scand J Thorac Cardiovasc Surg 1996;30(2):53-9. doi: 10.3109/14017439609107242. PMID: 8857675
Blood compatibility of two different types of membrane oxygenator during cardiopulmonary bypass in infants.
Gu YJ, Boonstra PW, Akkerman C, Mungroop H, Tigchelaar I, Van Oeveren W
Int J Artif Organs 1994 Oct;17(10):543-8. PMID: 7896428

Prognosis

Chemokine levels predict progressive liver disease in Down syndrome patients with transient abnormal myelopoiesis.
Kinjo T, Inoue H, Kusuda T, Fujiyoshi J, Ochiai M, Takahata Y, Honjo S, Koga Y, Hara T, Ohga S
Pediatr Neonatol 2019 Aug;60(4):382-388. Epub 2018 Sep 24 doi: 10.1016/j.pedneo.2018.09.005. PMID: 30314728
Loss of CXCR3 expression on memory B cells in individuals with long-standing type 1 diabetes.
Powell WE, Hanna SJ, Hocter CN, Robinson E, Davies J, Dunseath GJ, Luzio S, Farewell D, Wen L, Dayan CM, Price DA, Ladell K, Wong FS
Diabetologia 2018 Aug;61(8):1794-1803. Epub 2018 Jun 7 doi: 10.1007/s00125-018-4651-x. PMID: 29881878Free PMC Article
Serum levels of vascular dysfunction markers reflect disease severity and stage in systemic sclerosis patients.
Cossu M, Andracco R, Santaniello A, Marchini M, Severino A, Caronni M, Radstake T, Beretta L
Rheumatology (Oxford) 2016 Jun;55(6):1112-6. Epub 2016 Mar 17 doi: 10.1093/rheumatology/kew017. PMID: 26989111
Influence of two perfusion strategies on oxygen metabolism in paediatric cardiac surgery. Evaluation of the high-flow, low-resistance technique.
Schindler E, Photiadis J, Lagudka S, Fink C, Hraska V, Asfour B
Eur J Cardiothorac Surg 2010 Mar;37(3):651-7. Epub 2009 Sep 19 doi: 10.1016/j.ejcts.2009.07.050. PMID: 19766503
In vivo platelet activation with in vitro hyperaggregability to arachidonic acid in renal allograft recipients.
Frampton G, Parbtani A, Marchesi D, Duffus P, Livio M, Remuzzi G, Cameron JS
Kidney Int 1983 Mar;23(3):506-13. doi: 10.1038/ki.1983.48. PMID: 6405075

Clinical prediction guides

Preeclampsia at term: evidence of disease heterogeneity based on the profile of circulating cytokines and angiogenic factors.
Chaiworapongsa T, Romero R, Gomez-Lopez N, Suksai M, Gallo DM, Jung E, Berry SM, Awonuga A, Tarca AL, Bryant DR
Am J Obstet Gynecol 2024 Apr;230(4):450.e1-450.e18. Epub 2023 Oct 6 doi: 10.1016/j.ajog.2023.10.002. PMID: 37806612Free PMC Article
The role of chemerin in the pathogenesis of cholelithiasis in children and adolescents.
Zdanowicz K, Ryzko J, Bobrus-Chociej A, Wojtkowska M, Lebensztejn DM
J Paediatr Child Health 2021 Mar;57(3):371-375. Epub 2020 Oct 11 doi: 10.1111/jpc.15223. PMID: 33043555
Loss of CXCR3 expression on memory B cells in individuals with long-standing type 1 diabetes.
Powell WE, Hanna SJ, Hocter CN, Robinson E, Davies J, Dunseath GJ, Luzio S, Farewell D, Wen L, Dayan CM, Price DA, Ladell K, Wong FS
Diabetologia 2018 Aug;61(8):1794-1803. Epub 2018 Jun 7 doi: 10.1007/s00125-018-4651-x. PMID: 29881878Free PMC Article
Abnormal axon reflex-mediated sweating correlates with high state of anxiety in atopic dermatitis.
Kijima A, Murota H, Matsui S, Takahashi A, Kimura A, Kitaba S, Lee JB, Katayama I
Allergol Int 2012 Sep;61(3):469-73. Epub 2012 Jul 25 doi: 10.2332/allergolint.12-OA-0429. PMID: 22824978
Loss of circulating CD27+ memory B cells and CCR4+ T cells occurring in association with elevated EBV loads in XLP patients surviving primary EBV infection.
Malbran A, Belmonte L, Ruibal-Ares B, Baré P, Massud I, Parodi C, Felippo M, Hodinka R, Haines K, Nichols KE, de Bracco MM
Blood 2004 Mar 1;103(5):1625-31. Epub 2003 Nov 6 doi: 10.1182/blood-2003-07-2525. PMID: 14604960

Recent systematic reviews

Chronic fatigue syndrome and circulating cytokines: A systematic review.
Blundell S, Ray KK, Buckland M, White PD
Brain Behav Immun 2015 Nov;50:186-195. Epub 2015 Jul 3 doi: 10.1016/j.bbi.2015.07.004. PMID: 26148446

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