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Cutaneous leishmaniasis

MedGen UID:
9715
Concept ID:
C0023283
Disease or Syndrome
Synonyms: Cutaneous Leishmaniases; Cutaneous Leishmaniasis; Leishmaniases, Cutaneous; Leishmaniasis, Cutaneous
SNOMED CT: Cutaneous leishmaniasis (240637006)
 
Monarch Initiative: MONDO:0005446

Definition

Leishmaniasis affecting the skin. It is the most common form of leishmaniasis. It presents with erythematous macules and papules, and nodules which may eventually ulcerate. The lesions appear in the bite site in the exposed skin areas. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCutaneous leishmaniasis

Professional guidelines

PubMed

de Vries HJC, Schallig HD
Am J Clin Dermatol 2022 Nov;23(6):823-840. Epub 2022 Sep 14 doi: 10.1007/s40257-022-00726-8. PMID: 36103050Free PMC Article
Soto JA, Berman JD
Clin Infect Dis 2021 Oct 5;73(7):e2463-e2464. doi: 10.1093/cid/ciaa1461. PMID: 33128373
Jull AB, Cullum N, Dumville JC, Westby MJ, Deshpande S, Walker N
Cochrane Database Syst Rev 2015 Mar 6;2015(3):CD005083. doi: 10.1002/14651858.CD005083.pub4. PMID: 25742878Free PMC Article

Recent clinical studies

Etiology

de Vries HJC, Schallig HD
Am J Clin Dermatol 2022 Nov;23(6):823-840. Epub 2022 Sep 14 doi: 10.1007/s40257-022-00726-8. PMID: 36103050Free PMC Article
Novais FO, Amorim CF, Scott P
Front Immunol 2021;12:660183. Epub 2021 Mar 26 doi: 10.3389/fimmu.2021.660183. PMID: 33841444Free PMC Article
Aronson NE, Joya CA
Infect Dis Clin North Am 2019 Mar;33(1):101-117. doi: 10.1016/j.idc.2018.10.004. PMID: 30712756
Paniz-Mondolfi AE, Talhari C, García Bustos MF, Rosales T, Villamil-Gomez WE, Marquez M, Pérez Alvarez AM, Tálamo Sánchez AI, Rodriguez-Morales AJ
Int J Dermatol 2017 Dec;56(12):1328-1341. Epub 2017 Jul 25 doi: 10.1111/ijd.13664. PMID: 28741648
Reithinger R, Dujardin JC, Louzir H, Pirmez C, Alexander B, Brooker S
Lancet Infect Dis 2007 Sep;7(9):581-96. doi: 10.1016/S1473-3099(07)70209-8. PMID: 17714672

Diagnosis

Crecelius EM, Burnett MW
J Spec Oper Med 2021 Spring;21(1):113-114. doi: 10.55460/IMV2-JGWD. PMID: 33721318
Gurel MS, Tekin B, Uzun S
Clin Dermatol 2020 Mar-Apr;38(2):140-151. Epub 2019 Oct 24 doi: 10.1016/j.clindermatol.2019.10.008. PMID: 32513395
Aronson NE, Joya CA
Infect Dis Clin North Am 2019 Mar;33(1):101-117. doi: 10.1016/j.idc.2018.10.004. PMID: 30712756
Bahrami F, Harandi AM, Rafati S
Front Cell Infect Microbiol 2018;8:222. Epub 2018 Jun 26 doi: 10.3389/fcimb.2018.00222. PMID: 29998089Free PMC Article
Grevelink SA, Lerner EA
J Am Acad Dermatol 1996 Feb;34(2 Pt 1):257-72. doi: 10.1016/s0190-9622(96)80121-6. PMID: 8642091

Therapy

Iqbal K, Khalid S, McElroy CA, Adnan M, Khan GM, Dar MJ
Nanomedicine (Lond) 2022 Aug;17(20):1429-1447. Epub 2022 Oct 27 doi: 10.2217/nnm-2022-0077. PMID: 36301316
Aronson NE, Joya CA
Infect Dis Clin North Am 2019 Mar;33(1):101-117. doi: 10.1016/j.idc.2018.10.004. PMID: 30712756
Uliana SRB, Trinconi CT, Coelho AC
Parasitology 2018 Apr;145(4):464-480. Epub 2017 Jan 20 doi: 10.1017/S0031182016002523. PMID: 28103966
Jull AB, Cullum N, Dumville JC, Westby MJ, Deshpande S, Walker N
Cochrane Database Syst Rev 2015 Mar 6;2015(3):CD005083. doi: 10.1002/14651858.CD005083.pub4. PMID: 25742878Free PMC Article
Machado PR, Penna G
Curr Opin Infect Dis 2012 Apr;25(2):141-4. doi: 10.1097/QCO.0b013e3283509cac. PMID: 22248979

Prognosis

Gurel MS, Tekin B, Uzun S
Clin Dermatol 2020 Mar-Apr;38(2):140-151. Epub 2019 Oct 24 doi: 10.1016/j.clindermatol.2019.10.008. PMID: 32513395
Handler MZ, Patel PA, Kapila R, Al-Qubati Y, Schwartz RA
J Am Acad Dermatol 2015 Dec;73(6):911-26; 927-8. doi: 10.1016/j.jaad.2014.09.014. PMID: 26568336
Amer M, Amer A
Clin Dermatol 2014 Nov-Dec;32(6):744-51. Epub 2014 Mar 2 doi: 10.1016/j.clindermatol.2014.02.013. PMID: 25441467
Reithinger R, Dujardin JC, Louzir H, Pirmez C, Alexander B, Brooker S
Lancet Infect Dis 2007 Sep;7(9):581-96. doi: 10.1016/S1473-3099(07)70209-8. PMID: 17714672
Minodier P, Parola P
Travel Med Infect Dis 2007 May;5(3):150-8. Epub 2006 Oct 31 doi: 10.1016/j.tmaid.2006.09.004. PMID: 17448941

Clinical prediction guides

Çabalak M, Çulha G, Bal T, Kaya T, Çelik E
Turkiye Parazitol Derg 2021 Aug 4;45(3):227-229. doi: 10.4274/tpd.galenos.2021.21931. PMID: 34346882
Volpedo G, Pacheco-Fernandez T, Holcomb EA, Cipriano N, Cox B, Satoskar AR
Front Cell Infect Microbiol 2021;11:685296. Epub 2021 Jun 8 doi: 10.3389/fcimb.2021.685296. PMID: 34169006Free PMC Article
Paniz-Mondolfi AE, Talhari C, García Bustos MF, Rosales T, Villamil-Gomez WE, Marquez M, Pérez Alvarez AM, Tálamo Sánchez AI, Rodriguez-Morales AJ
Int J Dermatol 2017 Dec;56(12):1328-1341. Epub 2017 Jul 25 doi: 10.1111/ijd.13664. PMID: 28741648
Scorza BM, Carvalho EM, Wilson ME
Int J Mol Sci 2017 Jun 18;18(6) doi: 10.3390/ijms18061296. PMID: 28629171Free PMC Article
Von Stebut E
J Dtsch Dermatol Ges 2015 Mar;13(3):191-200; quiz 201. doi: 10.1111/ddg.12595. PMID: 25721626

Recent systematic reviews

Sabzevari S, Teshnizi SH, Shokri A, Bahrami F, Kouhestani F
Microb Pathog 2021 Mar;152:104721. Epub 2021 Feb 1 doi: 10.1016/j.micpath.2020.104721. PMID: 33539962
Taghipour A, Abdoli A, Ramezani A, Abolghazi A, Mofazzal Jahromi MA, Maani S, Heidar Nejadi SM, Rasti S, Shams M, Ghasemi E
Biol Trace Elem Res 2021 Oct;199(10):3918-3938. Epub 2021 Jan 6 doi: 10.1007/s12011-020-02505-0. PMID: 33405078
Panahi S, Abbasi M, Sayehmiri K, Sadegh S, Abdi J
Infect Disord Drug Targets 2021;21(2):173-179. doi: 10.2174/1871526520666200601164850. PMID: 32479248
Meireles CB, Maia LC, Soares GC, Teodoro IPP, Gadelha MDSV, da Silva CGL, de Lima MAP
Acta Trop 2017 Aug;172:240-254. Epub 2017 May 17 doi: 10.1016/j.actatropica.2017.05.022. PMID: 28526427
Jull AB, Cullum N, Dumville JC, Westby MJ, Deshpande S, Walker N
Cochrane Database Syst Rev 2015 Mar 6;2015(3):CD005083. doi: 10.1002/14651858.CD005083.pub4. PMID: 25742878Free PMC Article

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