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Items: 11

1.

Glioma

The presence of a glioma, which is a neoplasm of the central nervous system originating from a glial cell (astrocytes or oligodendrocytes). [from HPO]

MedGen UID:
9030
Concept ID:
C0017638
Neoplastic Process
2.

Glioblastoma

Glioblastomas are malignant astrocytic tumors (grade IV according to the WHO classification). [from ORDO]

MedGen UID:
42228
Concept ID:
C0017636
Neoplastic Process
3.

Glioblastoma multiforme

A tumor arising from glia in the central nervous system with macroscopic regions of necrosis and hemorrhage. Microscopically, glioblastoma multiforme is characterized by regions of pseudopalisading necrosis, pleomorphic nuclei and cells, and microvascular proliferation. [from HPO]

MedGen UID:
301585
Concept ID:
C1621958
Neoplastic Process
4.

Neoplasm of brain

A benign or malignant neoplasm that arises from or metastasizes to the brain. [from HPO]

MedGen UID:
14216
Concept ID:
C0006118
Neoplastic Process
5.

Oligoastrocytoma

Oligoastrocytoma is a type of low-grade glioma with a mixed astrocytoma and oligodendroglioma histology, manifesting with headaches, speech and motor problems, seizures and, in some, subarachnoid haemorrhage. [from ORDO]

MedGen UID:
154285
Concept ID:
C0547065
Neoplastic Process
6.

Neoplasm of the central nervous system

A neoplasm of the central nervous system. [from HPO]

MedGen UID:
88335
Concept ID:
C0085136
Neoplastic Process
7.

Protoplasmic astrocytoma

A rare variant of diffuse astrocytoma. It is predominantly composed of neoplastic astrocytes showing a small cell body with few, flaccid processes with a low content of glial filaments and scant GFAP expression. This lesion is not well defined and is considered by some authors as an occasional histopathological feature rather than a reproducibly identifiable variant. When occurring in children, this neoplasm may be difficult to separate from pilocytic juvenile astrocytoma. (Adapted from WHO) [from NCI]

MedGen UID:
87268
Concept ID:
C0334580
Neoplastic Process
8.

Neoplasm of the nervous system

A tumor (abnormal growth of tissue) of the nervous system. [from HPO]

MedGen UID:
45046
Concept ID:
C0027766
Neoplastic Process
9.

Aging

Progressive damage to mitochondrial DNA (mtDNA) during life is thought to contribute to aging processes. This notion is supported by the observation of an aging-related accumulation in human mtDNA of oxidative and alkylation derivatives of nucleotides, of small deletions and insertions, and of large deletions, although their low frequency raises questions about their functional significance (Michikawa et al., 1999). [from OMIM]

MedGen UID:
1376
Concept ID:
C0001811
Organism Function
10.

Astrocytoma

Astrocytoma is a neoplasm of the central nervous system derived from astrocytes. Astrocytes are a type of glial cell, and thus astrocytoma is a subtype of glioma. [from HPO]

MedGen UID:
438
Concept ID:
C0004114
Neoplastic Process
11.

Childhood astrocytic tumor

An astrocytic tumor appearing before the age of twenty one without designation of benign or malignant nor designated location. [from NCI]

MedGen UID:
272112
Concept ID:
C1321865
Neoplastic Process
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