GPL10687[RGSE] - GEO DataSets

Select item 2000247021.

Gene expression profiling of human atherosclerotic plaque: 290 peripheral plaques

(Submitter supplied) In order to identify potential new biomarkers of atherosclerotic plaque composition we performed a large scale analysis of gene expression patterns in human atherosclerotic lesions. Whole genome expression analysis of 101 peripheral plaques identified a robust gene signature (1514 genes) dominated by inflammatory processes, and cholesterol metabolism and storage genes. Specific pathways enriched in this signature included activation of the Toll-like receptor signaling pathway, T-cell activation, cholesterol efflux, oxidative stress response, inflammatory cytokine production, vasoconstriction and lysosomal activity. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL10687
290 Samples

Download data: CEL

Series

Accession:: GSE24702

ID:: 200024702

Analyze with GEO2R

Select item 2000244952.

Gene expression profiling of human atherosclerotic plaque: Carotid plaque

(Submitter supplied) In order to identify potential new biomarkers of atherosclerotic plaque composition we performed a large scale analysis of gene expression patterns in human atherosclerotic lesions. Whole genome expression analysis of 101 peripheral plaques identified a robust gene signature (1514 genes) dominated by inflammatory processes, and cholesterol metabolism and storage genes. Specific pathways enriched in this signature included activation of the Toll-like receptor signaling pathway, T-cell activation, cholesterol efflux, oxidative stress response, inflammatory cytokine production, vasoconstriction and lysosomal activity. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL10687
113 Samples

Download data: CEL

Series

Accession:: GSE24495

ID:: 200024495

Select item 2000233143.

Gene expression profiling of human atherosclerotic plaque

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platforms:: GPL4372 GPL10687
521 Samples

Download data: CEL

Series

Accession:: GSE23314

ID:: 200023314

Select item 2000250974.

Study of gene expression of human liver Hepatocellular carcinoma

(Submitter supplied) Hepatocellular carcinoma (HCC) affects millions of people worldwide and is a lethal malignancy for which there are no effective therapies. To identify prognostic gene markers for liver cancer, we conducted transcriptome profiling of frozen tissues (tumor and non-tumor) from 300 early-to-advanced stage HCCs plus 40 cirrhotic and 6 normal livers.